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Related papers: Pathology-Guided Virtual Staining Metric for Evalu…

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Photon Absorption Remote Sensing (PARS) enables label-free imaging of subcellular morphology by observing biomolecule specific absorption interactions. Coupled with deep-learning, PARS produces label-free virtual Hematoxylin and Eosin (H&E)…

The development of biophysical models for clinical applications is rapidly advancing in the research community, thanks to their predictive nature and their ability to assist the interpretation of clinical data. However, high-resolution and…

No-Reference Image Quality Assessment (NR-IQA) aims to estimate perceptual quality without access to a reference image of pristine quality. Learning an NR-IQA model faces a fundamental bottleneck: its need for a large number of costly human…

Computer Vision and Pattern Recognition · Computer Science 2026-03-18 Mahdi Naseri , Zhou Wang

Similarity metrics have played a significant role in computer vision to capture the underlying semantics of images. In recent years, advanced similarity metrics, such as the Learned Perceptual Image Patch Similarity (LPIPS), have emerged.…

Computer Vision and Pattern Recognition · Computer Science 2023-08-01 Sara Ghazanfari , Siddharth Garg , Prashanth Krishnamurthy , Farshad Khorrami , Alexandre Araujo

Foundation models have revolutionized the paradigm of digital pathology, as they leverage general-purpose features to emulate real-world pathological practices, enabling the quantitative analysis of critical histological patterns and the…

The histopathological analysis of whole-slide images (WSIs) is fundamental to cancer diagnosis but is a time-consuming and expert-driven process. While deep learning methods show promising results, dominant patch-based methods artificially…

Image and Video Processing · Electrical Eng. & Systems 2025-10-08 Alexander Weers , Alexander H. Berger , Laurin Lux , Peter Schüffler , Daniel Rueckert , Johannes C. Paetzold

Full-reference image quality assessment (FR-IQA) models generally operate by measuring the visual differences between a degraded image and its reference. However, existing FR-IQA models including both the classical ones (eg, PSNR and SSIM)…

Computer Vision and Pattern Recognition · Computer Science 2024-08-20 Kang Xiao , Xu Wang , Yulin He , Baoliang Chen , Xuelin Shen

Histological examination is a crucial step in an autopsy; however, the traditional histochemical staining of post-mortem samples faces multiple challenges, including the inferior staining quality due to autolysis caused by delayed fixation…

Tractable models of human perception have proved to be challenging to build. Hand-designed models such as MS-SSIM remain popular predictors of human image quality judgements due to their simplicity and speed. Recent modern deep learning…

Computer Vision and Pattern Recognition · Computer Science 2021-01-12 Sangnie Bhardwaj , Ian Fischer , Johannes Ballé , Troy Chinen

Accurate histopathological diagnosis often requires multiple differently stained tissue sections, a process that is time-consuming, labor-intensive, and environmentally taxing due to the use of multiple chemical stains. Recently, virtual…

Computer Vision and Pattern Recognition · Computer Science 2025-09-18 Jiabo MA , Wenqiang Li , Jinbang Li , Ziyi Liu , Linshan Wu , Fengtao Zhou , Li Liang , Ronald Cheong Kin Chan , Terence T. W. Wong , Hao Chen

The integration of artificial intelligence into digital pathology has the potential to automate and improve various tasks, such as image analysis and diagnostic decision-making. Yet, the inherent variability of tissues, together with the…

Image and Video Processing · Electrical Eng. & Systems 2023-02-14 Ariel Larey , Nati Daniel , Eliel Aknin , Yael Fisher , Yonatan Savir

Traditional image quality assessment (IQA) methods rely on mean opinion scores (MOS), which are resource-intensive to collect and fail to provide interpretable, localized feedback on specific image distortions. We overcome these limitations…

Computer Vision and Pattern Recognition · Computer Science 2026-05-05 Fadeel Sher Khan , Long N. Le , Abhinau K. Venkataramanan , Seok-Jun Lee , Hamid R. Sheikh

Infrared and visible image fusion is a powerful technique that combines complementary information from different modalities for downstream semantic perception tasks. Existing learning-based methods show remarkable performance, but are…

Computer Vision and Pattern Recognition · Computer Science 2023-08-09 Zhu Liu , Jinyuan Liu , Benzhuang Zhang , Long Ma , Xin Fan , Risheng Liu

Immunohistochemical (IHC) staining provides crucial molecular characterization of tissue samples and plays an indispensable role in the clinical examination and diagnosis of cancers. However, compared with the commonly used Hematoxylin and…

Computer Vision and Pattern Recognition · Computer Science 2026-01-07 Mingzhou Jiang , Jiaying Zhou , Nan Zeng , Mickael Li , Qijie Tang , Chao He , Huazhu Fu , Honghui He

Histological staining is a vital step used to diagnose various diseases and has been used for more than a century to provide contrast to tissue sections, rendering the tissue constituents visible for microscopic analysis by medical experts.…

Image and Video Processing · Electrical Eng. & Systems 2020-05-08 Yijie Zhang , Kevin de Haan , Yair Rivenson , Jingxi Li , Apostolos Delis , Aydogan Ozcan

The ability to classify images is dependent on having access to large labeled datasets and testing on data from the same domain that the model can train on. Classification becomes more challenging when dealing with new data from a different…

Computer Vision and Pattern Recognition · Computer Science 2023-10-20 Firas Al-Hindawi , Md Mahfuzur Rahman Siddiquee , Teresa Wu , Han Hu , Ying Sun

Hematoxylin and eosin (H&E)-stained slides are central to cancer diagnosis and monitoring, visualizing tissue architecture and cellular morphology. However, H&E lacks the molecular specificity needed to distinguish cell states and…

Image and Video Processing · Electrical Eng. & Systems 2026-04-14 Tushar Kataria , Beatrice Knudsen , Shireen Y. Elhabian

Virtual histology is an emerging field in biomedicine that enables three-dimensional tissue visualization using X-ray micro-computed tomography. However, the method still lacks the specificity of conventional histology, in which parts of…

We propose a virtual staining methodology based on Generative Adversarial Networks to map histopathology images of breast cancer tissue from H&E stain to PHH3 and vice versa. We use the resulting synthetic images to build Convolutional…

Image and Video Processing · Electrical Eng. & Systems 2020-03-18 Caner Mercan , Germonda Reijnen-Mooij , David Tellez Martin , Johannes Lotz , Nick Weiss , Marcel van Gerven , Francesco Ciompi

Image inpainting, the task of reconstructing missing segments in corrupted images using available data, faces challenges in ensuring consistency and fidelity, especially under information-scarce conditions. Traditional evaluation methods,…

Computer Vision and Pattern Recognition · Computer Science 2024-05-28 Tianyi Chen , Jianfu Zhang , Yan Hong , Yiyi Zhang , Liqing Zhang