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Ensuring the safety and reliability of large language models (LLMs) in clinical practice is critical to prevent patient harm. However, LLMs are advancing so rapidly that static benchmarks quickly become obsolete or prone to overfitting,…

This work introduces a latency-aware benchmarking framework for evaluating deep learning models in power system anomaly detection using high-fidelity, time-domain signals generated from an industry-grade electromagnetic transient simulator.…

Systems and Control · Electrical Eng. & Systems 2026-05-19 Emad Abukhousa , Saman Zonouz , A. P. Sakis Meliopoulos

Breast cancer remains a leading cause of cancer-related mortality worldwide. Early detection is critical, yet manual histopathology analysis is complex and subject to inter-observer variability. While deep neural network-based diagnostic…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Gul Sheeraz , Qun Chen , Liu Feiyu , Zhou Fengjin

Recently, prototype learning has emerged in semi-supervised medical image segmentation and achieved remarkable performance. However, the scarcity of labeled data limits the expressiveness of prototypes in previous methods, potentially…

Computer Vision and Pattern Recognition · Computer Science 2024-04-17 Lijian Li

Hypervariable T-cell receptors (TCR) play a key role in adaptive immunity, recognising a vast diversity of pathogen-derived antigens. High throughput sequencing of TCR repertoires (RepSeq) produces huge datasets of T-cell receptor sequences…

Retrosynthesis is essential for designing synthetic pathways for complex molecules and can be revolutionized by AI to automate and accelerate chemical synthesis planning for drug discovery and materials science. Here, we propose a…

Chemical Physics · Physics 2024-12-02 Seongeun Yun , Won Bo Lee

Background: While machine learning (ML) models are rapidly emerging as promising screening tools in critical care medicine, the identification of homogeneous subphenotypes within populations with heterogeneous conditions such as pediatric…

Lithium halides with the general formula Li$_x$M$_y$X$_6$, where M indicates transition metal ions and X halide anions are very actively studied as solid-state electrolytes, because of relatively low cost, high stability and Li…

Materials Science · Physics 2025-11-20 Davide Tisi , Sergey Pozdnyakov , Michele Ceriotti

Early and accurate diagnosis of Alzheimer's disease (AD) and its prodromal period mild cognitive impairment (MCI) is essential for the delayed disease progression and the improved quality of patients'life. The emerging computer-aided…

Image and Video Processing · Electrical Eng. & Systems 2021-07-29 Fan Zhang , Bo Pan , Pengfei Shao , Peng Liu , Shuwei Shen , Peng Yao , Ronald X. Xu

Disease modifying therapies for Alzheimer's disease demand precise timing decisions, yet current predictive models require longitudinal observations and provide no uncertainty quantification, rendering them impractical at the critical first…

Machine Learning · Computer Science 2026-04-13 Alireza Moayedikia , Sara Fin , Uffe Kock Wiil

We present a foundation modeling framework that leverages deep learning to uncover latent genetic signatures across the hematopoietic hierarchy. Our approach trains a fully connected autoencoder on multipotent progenitor cells, reducing…

Machine Learning · Computer Science 2025-03-27 Gabriel Bo , Justin Gu , Christopher Sun

Identifying amyloid-beta positive patients is crucial for determining eligibility for Alzheimer's disease (AD) clinical trials and new disease-modifying treatments, but currently requires PET or CSF sampling. Previous MRI-based deep…

Image and Video Processing · Electrical Eng. & Systems 2025-08-06 Donghoon Kim , Jon Andre Ottesen , Ashwin Kumar , Brandon C. Ho , Elsa Bismuth , Christina B. Young , Elizabeth Mormino , Greg Zaharchuk

The application of machine learning techniques to the medical domain is especially challenging due to the required level of precision and the incurrence of huge risks of minute errors. Employing these techniques to a more complex subdomain…

Computer Vision and Pattern Recognition · Computer Science 2021-10-19 Ekta Gavas , Kaustubh Olpadkar

In computational pathology, we often face a scarcity of annotations and a large amount of unlabeled data. One method for dealing with this is semi-supervised learning which is commonly split into a self-supervised pretext task and a…

Computer Vision and Pattern Recognition · Computer Science 2022-03-15 Manuel Tran , Sophia J. Wagner , Melanie Boxberg , Tingying Peng

Predicting highrisk vascular diseases is a significant issue in the medical domain. Most predicting methods predict the prognosis of patients from pathological and radiological measurements, which are expensive and require much time to be…

Machine Learning · Computer Science 2017-12-04 You Jin Kim , Yun-Geun Lee , Jeong Whun Kim , Jin Joo Park , Borim Ryu , Jung-Woo Ha

We consider the problem in precision health of grouping people into subpopulations based on their degree of vulnerability to a risk factor. These subpopulations cannot be discovered with traditional clustering techniques because their…

Machine Learning · Statistics 2018-12-11 Alexander New , Kristin P. Bennett

We present a global explainability method to characterize sources of errors in the histology prediction task of our real-world multitask convolutional neural network (MTCNN)-based deep abstaining classifier (DAC), for automated annotation…

The latent representation in learned image compression encompasses channel-wise, local spatial, and global spatial correlations, which are essential for the entropy model to capture for conditional entropy minimization. Efficiently…

Image and Video Processing · Electrical Eng. & Systems 2025-10-29 Wei Jiang , Jiayu Yang , Yongqi Zhai , Feng Gao , Ronggang Wang

Sparse linear regression methods for high-dimensional data commonly assume that residuals have constant variance, which can be violated in practice. For example, Aphasia Quotient (AQ) is a critical measure of language impairment and informs…

Methodology · Statistics 2024-07-16 Anja Zgodic , Ray Bai , Jiajia Zhang , Yuan Wang , Chris Rorden , Alexander McLain

Efficient label acquisition processes are key to obtaining robust classifiers. However, data labeling is often challenging and subject to high levels of label noise. This can arise even when classification targets are well defined, if…

Artificial Intelligence · Computer Science 2018-08-22 Olivier Deiss , Siddharth Biswal , Jing Jin , Haoqi Sun , M. Brandon Westover , Jimeng Sun