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Large language models (LLMs) show promise in healthcare, but hallucinations remain a major barrier to clinical use. We present CHECK, a continuous-learning framework that integrates structured clinical databases with a classifier grounded…

Adversarial robustness of deep models is pivotal in ensuring safe deployment in real world settings, but most modern defenses have narrow scope and expensive costs. In this paper, we propose a self-supervised method to detect adversarial…

Cryptography and Security · Computer Science 2021-09-01 Mazda Moayeri , Soheil Feizi

This research introduces a multi-horizon contingency model predictive control (CMPC) framework in which classes of robust MPC (RMPC) algorithms are combined with classes of learning-based MPC (LB-MPC) algorithms to enable safe learning. We…

Optimization and Control · Mathematics 2025-05-30 Merlijne Geurts , Tren Baltussen , Alexander Katriniok , Maurice Heemels

Multivariate, heteroscedastic errors complicate statistical inference in many large-scale denoising problems. Empirical Bayes is attractive in such settings, but standard parametric approaches rest on assumptions about the form of the prior…

Statistics Theory · Mathematics 2024-01-02 Jake A. Soloff , Adityanand Guntuboyina , Bodhisattva Sen

Histopathological image classification is an important task in medical image analysis. Recent approaches generally rely on weakly supervised learning due to the ease of acquiring case-level labels from pathology reports. However,…

Computer Vision and Pattern Recognition · Computer Science 2024-11-14 Bodong Zhang , Hamid Manoochehri , Man Minh Ho , Fahimeh Fooladgar , Yosep Chong , Beatrice S. Knudsen , Deepika Sirohi , Tolga Tasdizen

Coronary Artery Disease (CAD) results from plaque deposit in a coronary artery. Early diagnosis is imperative, so a non-invasive detection method is being developed to identify acoustic signals caused by partial occlusions in the artery.…

Signal Processing · Electrical Eng. & Systems 2024-04-25 Bansi Mandalia , Steve Greenwald , Simon Shaw , Gregory Slabaugh

Epilepsy represents the most prevalent neurological disease in the world. One-third of people suffering from mesial temporal lobe epilepsy (MTLE) exhibit drug resistance, urging the need to develop new treatments. A key part in anti-seizure…

Patch classification models based on deep learning have been utilized in whole-slide images (WSI) of H&E-stained tissue samples to assist pathologists in grading follicular lymphoma patients. However, these approaches still require…

Closed-loop neural interfaces with on-chip machine learning can detect and suppress disease symptoms in neurological disorders or restore lost functions in paralyzed patients. While high-density neural recording can provide rich neural…

Signal Processing · Electrical Eng. & Systems 2023-03-21 Uisub Shin , Cong Ding , Bingzhao Zhu , Yashwanth Vyza , Alix Trouillet , Emilie C. M. Revol , Stéphanie P. Lacour , Mahsa Shoaran

Large language models (LLMs) are increasingly used as generators in iterative neural architecture search (NAS), yet no formal convergence theory exists for this class of algorithms. We model iterative LLM-NAS as a parametric Cross-Entropy…

Machine Learning · Computer Science 2026-05-29 Santosh Premi Adhikari , Radu Timofte , Dmitry Ignatov

Automatic detection of lymphocyte in H&E images is a necessary first step in lots of tissue image analysis algorithms. An accurate and robust automated lymphocyte detection approach is of great importance in both computer science and…

Computer Vision and Pattern Recognition · Computer Science 2016-12-13 Jianxu Chen , Chukka Srinivas

Early detection of Alzheimer's Dementia (AD) and Mild Cognitive Impairment (MCI) is critical for timely intervention, yet current diagnostic approaches remain resource-intensive and invasive. Speech, encompassing both acoustic and…

Latent class analysis (LCA) is a useful tool to investigate the heterogeneity of a disease population with time-to-event data. We propose a new method based on non-parametric maximum likelihood estimator (NPMLE), which facilitates…

Methodology · Statistics 2022-02-03 Teng Fei , John Hanfelt , Limin Peng

Memristor has great application prospects in various high-performance electronic systems, such as memory, artificial intelligence, and neural networks, due to its fast speed, nano-scale dimensions, and low-power consumption. However,…

Applied Physics · Physics 2018-12-04 Wei Hu , Du Yongqian , Haibo Luo , Chuandong Chen , Rongshan Wei

Learning-based lossless compressors play a crucial role in large-scale genomic database backup, storage, transmission, and management. However, their 1) inadequate compression ratio, 2) low compression \& decompression throughput, and 3)…

Machine Learning · Computer Science 2025-07-18 Hui Sun , Yanfeng Ding , Liping Yi , Huidong Ma , Gang Wang , Xiaoguang Liu , Cheng Zhong , Wentong Cai

Alzheimer's disease (AD) progresses through distinct stages, from early mild cognitive impairment (EMCI) to late mild cognitive impairment (LMCI) and eventually to AD. Accurate identification of these stages, especially distinguishing LMCI…

Computer Vision and Pattern Recognition · Computer Science 2025-01-13 Aswini Kumar Patra , Soraisham Elizabeth Devi , Tejashwini Gajurel

The ALICE High Level Trigger has to process data online, in order to select interesting (sub)events, or to compress data efficiently by modeling techniques.Focusing on the main data source, the Time Projection Chamber (TPC), we present two…

Instrumentation and Detectors · Physics 2009-11-10 V. Lindenstruth , C. Loizides , D. Roehrich , B. Skaali , T. Steinbeck , R. Stock , H. Tilsner , K. Ullaland , A. Vestbo , T. Vik

Breast dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) plays an important role in the screening and prognosis assessment of high-risk breast cancer. The segmentation of cancerous regions is essential useful for the subsequent…

Image and Video Processing · Electrical Eng. & Systems 2023-06-30 Yuming Zhong , Yi Wang

CXRs are a crucial and extraordinarily common diagnostic tool, leading to heavy research for CAD solutions. However, both high classification accuracy and meaningful model predictions that respect and incorporate clinical taxonomies are…

Computer Vision and Pattern Recognition · Computer Science 2021-01-01 Haomin Chen , Shun Miao , Daguang Xu , Gregory D. Hager , Adam P. Harrison

Large language models (LLMs) often suffer from hallucinations due to error accumulation in autoregressive decoding, where suboptimal early token choices misguide subsequent generation. Although multi-path decoding can improve robustness by…

Computation and Language · Computer Science 2026-05-21 Tianyu Zheng , Hong Wu , Jiaji Zhong
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