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Diffusion models have significantly advanced the fields of image, audio, and video generation, but they depend on an iterative sampling process that causes slow generation. To overcome this limitation, we propose consistency models, a new…

Machine Learning · Computer Science 2023-06-01 Yang Song , Prafulla Dhariwal , Mark Chen , Ilya Sutskever

Medical generative models, acknowledged for their high-quality sample generation ability, have accelerated the fast growth of medical applications. However, recent works concentrate on separate medical generation models for distinct medical…

Image and Video Processing · Electrical Eng. & Systems 2024-03-08 Chenlu Zhan , Yu Lin , Gaoang Wang , Hongwei Wang , Jian Wu

Modern deep learning methods have achieved impressive results across tasks from disease classification, estimating continuous biomarkers, to generating realistic medical images. Most of these approaches are trained to model conditional…

Spatial profiling technologies in biology, such as imaging mass cytometry (IMC) and spatial transcriptomics (ST), generate high-dimensional, multi-channel data with strong spatial alignment and complex inter-channel relationships.…

Machine Learning · Computer Science 2025-07-08 Haoran Zhang , Mingyuan Zhou , Wesley Tansey

Diffusion Models (DMs) have achieved great success in image generation and other fields. By fine sampling through the trajectory defined by the SDE/ODE solver based on a well-trained score model, DMs can generate remarkable high-quality…

Computer Vision and Pattern Recognition · Computer Science 2024-06-10 Bowen Zheng , Tianming Yang

Recent advances in generative medical models are constrained by modality-specific scenarios that hinder the integration of complementary evidence from imaging, pathology, and clinical notes. This fragmentation limits their evolution into…

Computer Vision and Pattern Recognition · Computer Science 2025-10-08 Jiawei Mao , Yuhan Wang , Lifeng Chen , Can Zhao , Yucheng Tang , Dong Yang , Liangqiong Qu , Daguang Xu , Yuyin Zhou

Recently, the emergence of diffusion models has opened up new opportunities for single-view reconstruction. However, all the existing methods represent the target object as a closed mesh devoid of any structural information, thus neglecting…

Graphics · Computer Science 2024-05-28 Anran Liu , Cheng Lin , Yuan Liu , Xiaoxiao Long , Zhiyang Dou , Hao-Xiang Guo , Ping Luo , Wenping Wang

Molecule generation, especially generating 3D molecular geometries from scratch (i.e., 3D \textit{de novo} generation), has become a fundamental task in drug designs. Existing diffusion-based 3D molecule generation methods could suffer from…

Machine Learning · Computer Science 2022-09-14 Lei Huang , Hengtong Zhang , Tingyang Xu , Ka-Chun Wong

Prompt learning has demonstrated promising results in fine-tuning pre-trained multimodal models. However, the performance improvement is limited when applied to more complex and fine-grained tasks. The reason is that most existing methods…

Computer Vision and Pattern Recognition · Computer Science 2025-05-01 Weicai Yan , Wang Lin , Zirun Guo , Ye Wang , Fangming Feng , Xiaoda Yang , Zehan Wang , Tao Jin

Diffusion models are emerging expressive generative models, in which a large number of time steps (inference steps) are required for a single image generation. To accelerate such tedious process, reducing steps uniformly is considered as an…

Computer Vision and Pattern Recognition · Computer Science 2023-09-26 Lijiang Li , Huixia Li , Xiawu Zheng , Jie Wu , Xuefeng Xiao , Rui Wang , Min Zheng , Xin Pan , Fei Chao , Rongrong Ji

Diffusion models, a powerful and universal generative AI technology, have achieved tremendous success in computer vision, audio, reinforcement learning, and computational biology. In these applications, diffusion models provide flexible…

Machine Learning · Computer Science 2024-04-12 Minshuo Chen , Song Mei , Jianqing Fan , Mengdi Wang

3D molecule generation is crucial for drug discovery and material science, requiring models to process complex multi-modalities, including atom types, chemical bonds, and 3D coordinates. A key challenge is integrating these modalities of…

Machine Learning · Computer Science 2025-10-14 Yanchen Luo , Zhiyuan Liu , Yi Zhao , Sihang Li , Hengxing Cai , Kenji Kawaguchi , Tat-Seng Chua , Yang Zhang , Xiang Wang

Goal-directed molecular generation requires satisfying heterogeneous constraints such as protein--ligand compatibility and multi-objective drug-like properties, yet existing methods often optimize these constraints in isolation, failing to…

Machine Learning · Computer Science 2026-04-14 Yanting Li , Zhuoyang Jiang , Enyan Dai , Lei Wang , Wen-Cai Ye , Li Liu

This paper presents DNAct, a language-conditioned multi-task policy framework that integrates neural rendering pre-training and diffusion training to enforce multi-modality learning in action sequence spaces. To learn a generalizable…

Robotics · Computer Science 2024-03-11 Ge Yan , Yueh-Hua Wu , Xiaolong Wang

Current 4D generation methods have achieved noteworthy efficacy with the aid of advanced diffusion generative models. However, these methods lack multi-view spatial-temporal modeling and encounter challenges in integrating diverse prior…

Computer Vision and Pattern Recognition · Computer Science 2024-10-23 Haiyu Zhang , Xinyuan Chen , Yaohui Wang , Xihui Liu , Yunhong Wang , Yu Qiao

Recent advances in generative diffusion models have enabled the previously unfeasible capability of generating 3D assets from a single input image or a text prompt. In this work, we aim to enhance the quality and functionality of these…

Computer Vision and Pattern Recognition · Computer Science 2024-04-03 Xiyi Chen , Marko Mihajlovic , Shaofei Wang , Sergey Prokudin , Siyu Tang

Diffusion models have emerged as a leading framework in generative modeling, poised to transform the traditionally slow and costly process of drug discovery. This review provides a systematic comparison of their application in designing two…

Machine Learning · Computer Science 2025-11-27 Yiquan Wang , Yahui Ma , Yuhan Chang , Jiayao Yan , Jialin Zhang , Minnuo Cai , Kai Wei

Masked diffusion models (MDM) are powerful generative models for discrete data that generate samples by progressively unmasking tokens in a sequence. Each token can take one of two states: masked or unmasked. We observe that token sequences…

Machine Learning · Computer Science 2025-10-23 Chen-Hao Chao , Wei-Fang Sun , Hanwen Liang , Chun-Yi Lee , Rahul G. Krishnan

Audio-driven portrait animation aims to synthesize portrait videos that are conditioned by given audio. Animating high-fidelity and multimodal video portraits has a variety of applications. Previous methods have attempted to capture…

Computer Vision and Pattern Recognition · Computer Science 2023-07-20 Yunfei Liu , Lijian Lin , Fei Yu , Changyin Zhou , Yu Li

We present \textbf{LLaDA-o}, an effective and length-adaptive omni diffusion model for multimodal understanding and generation. LLaDA-o is built on a Mixture of Diffusion (MoD) framework that decouples discrete masked diffusion for text…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Zebin You , Xiaolu Zhang , Jun Zhou , Chongxuan Li , Ji-Rong Wen
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