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Diffusion Models have become a cornerstone of modern generative AI for their exceptional generation quality and controllability. However, their inherent \textit{multi-step iterations} and \textit{complex backbone networks} lead to…

Designing new molecules is essential for drug discovery and material science. Recently, deep generative models that aim to model molecule distribution have made promising progress in narrowing down the chemical research space and generating…

Biomolecules · Quantitative Biology 2023-06-06 Han Huang , Leilei Sun , Bowen Du , Weifeng Lv

Generative models such as diffusion models, excel at capturing high-dimensional distributions with diverse input modalities, e.g. robot trajectories, but are less effective at multi-step constraint reasoning. Task and Motion Planning (TAMP)…

Data imputation and data generation have important applications for many domains, like healthcare and finance, where incomplete or missing data can hinder accurate analysis and decision-making. Diffusion models have emerged as powerful…

Machine Learning · Computer Science 2025-06-10 Mario Villaizán-Vallelado , Matteo Salvatori , Carlos Segura , Ioannis Arapakis

Diffusion models (DMs) are a powerful generative framework that have attracted significant attention in recent years. However, the high computational cost of training DMs limits their practical applications. In this paper, we start with a…

Machine Learning · Computer Science 2024-04-12 Tianshuo Xu , Peng Mi , Ruilin Wang , Yingcong Chen

Existing segmentation models trained on a single medical imaging dataset often lack robustness when encountering unseen organs or tumors. Developing a robust model capable of identifying rare or novel tumor categories not present during…

Computer Vision and Pattern Recognition · Computer Science 2025-07-02 Rong Wu , Ziqi Chen , Liming Zhong , Heng Li , Hai Shu

In medical image segmentation tasks, diffusion models have shown significant potential. However, mainstream diffusion models suffer from drawbacks such as multiple sampling times and slow prediction results. Recently, consistency models, as…

Computer Vision and Pattern Recognition · Computer Science 2024-05-16 Kejia Zhang , Lan Zhang , Haiwei Pan , Baolong Yu

Despite the remarkable success of diffusion models in text-to-image generation, their effectiveness in grounded visual editing and compositional control remains challenging. Motivated by advances in self-supervised learning and in-context…

Computer Vision and Pattern Recognition · Computer Science 2025-07-21 Shreya Kadambi , Risheek Garrepalli , Shubhankar Borse , Munawar Hyatt , Fatih Porikli

Acquiring aligned visuo-tactile datasets is slow and costly, requiring specialised hardware and large-scale data collection. Synthetic generation is promising, but prior methods are typically single-modality, limiting cross-modal learning.…

Computer Vision and Pattern Recognition · Computer Science 2026-02-24 Sirine Bhouri , Lan Wei , Jian-Qing Zheng , Dandan Zhang

The scarcity and complexity of voxel-level annotations in 3D medical imaging present significant challenges, particularly due to the domain gap between labeled datasets from well-resourced centers and unlabeled datasets from less-resourced…

Computer Vision and Pattern Recognition · Computer Science 2024-08-13 Haifan Gong , Yitao Wang , Yihan Wang , Jiashun Xiao , Xiang Wan , Haofeng Li

We introduce MMaDA, a novel class of multimodal diffusion foundation models designed to achieve superior performance across diverse domains such as textual reasoning, multimodal understanding, and text-to-image generation. The approach is…

Computer Vision and Pattern Recognition · Computer Science 2025-09-26 Ling Yang , Ye Tian , Bowen Li , Xinchen Zhang , Ke Shen , Yunhai Tong , Mengdi Wang

Recent advances in diffusion models have demonstrated their strong capabilities in generating high-fidelity samples from complex distributions through an iterative refinement process. Despite the empirical success of diffusion models in…

Robotics · Computer Science 2024-07-03 Chaoyi Pan , Zeji Yi , Guanya Shi , Guannan Qu

The performance of pre-trained masked diffusion models is often constrained by their sampling procedure, which makes decisions irreversible and struggles in low-step generation regimes. We introduce a novel sampling algorithm that works…

Diffusion Models (DMs) have demonstrated state-of-the-art performance in content generation without requiring adversarial training. These models are trained using a two-step process. First, a forward - diffusion - process gradually adds…

Computer Vision and Pattern Recognition · Computer Science 2024-03-13 Anwaar Ulhaq , Naveed Akhtar

Learning from a large corpus of data, pre-trained models have achieved impressive progress nowadays. As popular generative pre-training, diffusion models capture both low-level visual knowledge and high-level semantic relations. In this…

Computer Vision and Pattern Recognition · Computer Science 2023-03-20 Chaofan Ma , Yuhuan Yang , Chen Ju , Fei Zhang , Jinxiang Liu , Yu Wang , Ya Zhang , Yanfeng Wang

Dataset distillation has emerged as an effective strategy, significantly reducing training costs and facilitating more efficient model deployment. Recent advances have leveraged generative models to distill datasets by capturing the…

Computer Vision and Pattern Recognition · Computer Science 2025-05-27 Jeffrey A. Chan-Santiago , Praveen Tirupattur , Gaurav Kumar Nayak , Gaowen Liu , Mubarak Shah

Recent progress in image generation has sparked research into controlling these models through condition signals, with various methods addressing specific challenges in conditional generation. Instead of proposing another specialized…

Computer Vision and Pattern Recognition · Computer Science 2025-04-08 Xirui Li , Charles Herrmann , Kelvin C. K. Chan , Yinxiao Li , Deqing Sun , Chao Ma , Ming-Hsuan Yang

Recent advances in continuous generative models, including multi-step approaches like diffusion and flow-matching (typically requiring 8-1000 sampling steps) and few-step methods such as consistency models (typically 1-8 steps), have…

Machine Learning · Computer Science 2025-05-21 Peng Sun , Yi Jiang , Tao Lin

While recent multimodal large language models (MLLMs) have made impressive strides, they predominantly employ a conventional autoregressive architecture as their backbone, leaving significant room to explore effective and efficient…

Computer Vision and Pattern Recognition · Computer Science 2026-03-09 Lijiang Li , Zuwei Long , Yunhang Shen , Heting Gao , Haoyu Cao , Xing Sun , Caifeng Shan , Ran He , Chaoyou Fu

Recent remarkable advancements in geometric deep generative models, coupled with accumulated structural data, enable structure-based drug design (SBDD) using only target protein information. However, existing models often struggle to…

Biomolecules · Quantitative Biology 2026-03-09 Joongwon Lee , Wonho Zhung , Jisu Seo , Woo Youn Kim