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Oculomics - the concept of predicting systemic diseases, such as cardiovascular disease and dementia, through retinal imaging - has advanced rapidly due to the data efficiency of transformer-based foundation models like RETFound.…

Machine Learning · Computer Science 2026-01-29 Hyunmin Kim , Yukun Zhou , Rahul A. Jonas , Lie Ju , Sunjin Hwang , Pearse A. Keane , Siegfried K. Wagner

Handling incomplete and heterogeneous data remains a central challenge in real-world machine learning, where missing values may follow complex mechanisms (MCAR, MAR, MNAR) and features can be of mixed types (numerical and categorical).…

Machine Learning · Computer Science 2025-07-30 Youran Zhou , Mohamed Reda Bouadjenek , Jonathan Wells , Sunil Aryal

The interpretation of chest radiographs is an essential task for the detection of thoracic diseases and abnormalities. However, it is a challenging problem with high inter-rater variability and inherent ambiguity due to inconclusive…

Computer Vision and Pattern Recognition · Computer Science 2019-06-20 Florin C. Ghesu , Bogdan Georgescu , Eli Gibson , Sebastian Guendel , Mannudeep K. Kalra , Ramandeep Singh , Subba R. Digumarthy , Sasa Grbic , Dorin Comaniciu

The management of hyperglycemia in hospitalized patients has a significant impact on both morbidity and mortality. Therefore, it is important to predict the need for diabetic patients to be hospitalized. However, using standard machine…

Artificial Intelligence · Computer Science 2022-08-02 Shaina Raza

Understanding treatment effect heterogeneity is vital to many scientific fields because the same treatment may affect different individuals differently. Quantile regression provides a natural framework for modeling such heterogeneity. We…

Methodology · Statistics 2023-07-12 Alexander Giessing , Jingshen Wang

The availability of a large amount of electronic health records (EHR) provides huge opportunities to improve health care service by mining these data. One important application is clinical endpoint prediction, which aims to predict whether…

Artificial Intelligence · Computer Science 2018-11-20 Luchen Liu , Jianhao Shen , Ming Zhang , Zichang Wang , Jian Tang

Data heterogeneity plays a pivotal role in determining the performance of machine learning (ML) systems. Traditional algorithms, which are typically designed to optimize average performance, often overlook the intrinsic diversity within…

Machine Learning · Computer Science 2025-06-03 Jiashuo Liu , Peng Cui

Flexible estimation of heterogeneous treatment effects lies at the heart of many statistical challenges, such as personalized medicine and optimal resource allocation. In this paper, we develop a general class of two-step algorithms for…

Machine Learning · Statistics 2020-08-07 Xinkun Nie , Stefan Wager

Medical large vision-language Models (Med-LVLMs) have shown promise in clinical applications but suffer from factual inaccuracies and unreliable outputs, posing risks in real-world diagnostics. While RAG has emerged as a potential solution,…

Computation and Language · Computer Science 2026-05-05 Zhe Chen , Yusheng Liao , Zhiyuan Zhu , Haolin Li , Hongcheng Liu , Yanfeng Wang , Yu Wang

Similarity measure as a fundamental task in heterogeneous information network analysis has been applied to many areas, e.g., product recommendation, clustering and Web search. Most of the existing metrics depend on the meta-path or…

Databases · Computer Science 2018-05-24 Yu Zhou , Jianbin Huang , Heli Sun , Yizhou Sun

We introduce HTAD, a novel model for diagnosis prediction using Electronic Health Records (EHR) represented as Heterogeneous Information Networks. Recent studies on modeling EHR have shown success in automatically learning representations…

Machine Learning · Computer Science 2019-12-24 Anahita Hosseini , Tyler Davis , Majid Sarrafzadeh

Heterogeneity is a fundamental characteristic of cancer. To accommodate heterogeneity, subgroup identification has been extensively studied and broadly categorized into unsupervised and supervised analysis. Compared to unsupervised…

Methodology · Statistics 2026-02-25 Xing Qin , Xu Liu , Shuangge Ma , Mengyun Wu

Due to the complexity of the human body, most diseases present a high inter-personal variability in the way they manifest, i.e. in their phenotype, which has important clinical repercussions - as for instance the difficulty in defining…

Physics and Society · Physics 2018-06-06 Massimiliano Zanin , Juan Manuel Tuñas , Ernestina Menasalvas

This paper introduces a flexible time-varying network vector autoregressive model framework for large-scale time series. A latent group structure is imposed on the heterogeneous and node-specific time-varying momentum and network spillover…

Methodology · Statistics 2024-03-12 Degui Li , Bin Peng , Songqiao Tang , Weibiao Wu

Treatment effect heterogeneity occurs when individual characteristics influence the effect of a treatment. We propose a novel approach that combines prognostic score matching and conditional inference trees to characterize effect…

When evaluating the efficacy of social programs and medical treatments using randomized experiments, the estimated overall average causal effect alone is often of limited value and the researchers must investigate when the treatments do and…

Applications · Statistics 2013-05-27 Kosuke Imai , Marc Ratkovic

Multiresponse data with complex group structures in both responses and predictors arises in many fields, yet, due to the difficulty in identifying complex group structures, only a few methods have been studied on this problem. We propose a…

Methodology · Statistics 2022-08-16 Weixiong Liang , Yuehan Yang

Radiology reports provide detailed descriptions of medical imaging integrated with patients' medical histories, while report writing is traditionally labor-intensive, increasing radiologists' workload and the risk of diagnostic errors.…

Computer Vision and Pattern Recognition · Computer Science 2024-07-23 Fuying Wang , Shenghui Du , Lequan Yu

In this paper we study the problems of estimating heterogeneity in causal effects in experimental or observational studies and conducting inference about the magnitude of the differences in treatment effects across subsets of the…

Machine Learning · Statistics 2022-06-08 Susan Athey , Guido Imbens

We introduce a two-parameter ensemble of random discrete-time Markov models that simultaneously captures critical slowing down and broken detailed balance. Extending a previously studied heterogeneous Markov ensemble, we incorporate…

Disordered Systems and Neural Networks · Physics 2026-02-06 Faheem Mosam , Eric De Giuli