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The potential of deep learning in clinical speech processing is immense, yet the hurdles of limited and imbalanced clinical data samples loom large. This article addresses these challenges by showcasing the utilization of automatic speech…

Automatic detection of Parkinson's disease (PD) from speech is a promising non-invasive diagnostic tool, but it raises significant privacy concerns. Speaker anonymization mitigates these risks, but it may suppress the pathological…

Sound · Computer Science 2026-03-10 Carlos Franzreb , Francisco Teixeira , Ben Luks , Sebastian Möller , Alberto Abad

The detection of pathologies from speech features is usually defined as a binary classification task with one class representing a specific pathology and the other class representing healthy speech. In this work, we train neural networks,…

Audio and Speech Processing · Electrical Eng. & Systems 2023-08-02 Dominik Wagner , Ilja Baumann , Franziska Braun , Sebastian P. Bayerl , Elmar Nöth , Korbinian Riedhammer , Tobias Bocklet

Parkinson's Disease PD is a progressive neurodegenerative disorder that affects motor and cognitive functions with early diagnosis being critical for effective clinical intervention Electroencephalography EEG offers a noninvasive and…

Parkinson's disease is the world's fastest-growing neurological disorder. Research to elucidate the mechanisms of Parkinson's disease and automate diagnostics would greatly improve the treatment of patients with Parkinson's disease. Current…

Machine Learning · Computer Science 2024-02-20 Charlie Tran , Kai Shen , Kang Liu , Akshay Ashok , Adolfo Ramirez-Zamora , Jinghua Chen , Yulin Li , Ruogu Fang

We present a web-based framework to screen for Parkinson's disease (PD) by allowing users to perform neurological tests in their homes. Our web framework guides the users to complete three tasks involving speech, facial expression, and…

Human-Computer Interaction · Computer Science 2023-11-22 Md Saiful Islam , Sangwu Lee , Abdelrahman Abdelkader , Sooyong Park , Ehsan Hoque

Developing objective methods for assessing the severity of Parkinson's disease (PD) is crucial for improving the diagnosis and treatment. This study proposes two sets of novel features derived from the single frequency filtering (SFF)…

Audio and Speech Processing · Electrical Eng. & Systems 2023-08-21 Sudarsana Reddy Kadiri , Manila Kodali , Paavo Alku

There is great interest in developing radiological classifiers for diagnosis, staging, and predictive modeling in progressive diseases such as Parkinson's disease (PD), a neurodegenerative disease that is difficult to detect in its early…

Speech Activity Detection (SAD) systems often misclassify singing as speech, leading to degraded performance in applications such as dialogue enhancement and automatic speech recognition. We introduce Singing-Robust Speech Activity…

Audio and Speech Processing · Electrical Eng. & Systems 2025-12-11 Philipp Grundhuber , Mhd Modar Halimeh , Martin Strauß , Emanuël A. P. Habets

Background: Parkinson's disease (PD) is a prevalent long-term neurodegenerative disease. Though the diagnostic criteria of PD are relatively well defined, the current medical imaging diagnostic procedures are expertise-demanding, and thus…

Quantitative Methods · Quantitative Biology 2019-02-27 Jiahang Xu , Fangyang Jiao , Yechong Huang , Xinzhe Luo , Qian Xu , Ling Li , Xueling Liu , Chuantao Zuo , Ping Wu , Xiahai Zhuang

The paper presents a novel approach, based on deep learning, for diagnosis of Parkinson's disease through medical imaging. The approach includes analysis and use of the knowledge extracted by Deep Convolutional and Recurrent Neural Networks…

Machine Learning · Computer Science 2019-11-26 James Wingate , Ilianna Kollia , Luc Bidaut , Stefanos Kollias

Computer audition (CA) has been demonstrated to be efficient in healthcare domains for speech-affecting disorders (e.g., autism spectrum, depression, or Parkinson's disease) and body sound-affecting abnormalities (e. g., abnormal bowel…

Sound · Computer Science 2020-12-10 Kun Qian , Bjorn W. Schuller , Yoshiharu Yamamoto

Speech-based depression detection has shown promise as an objective diagnostic tool, yet the cross-linguistic robustness of acoustic markers and their neurobiological underpinnings remain underexplored. This study extends Cross-Data…

Audio and Speech Processing · Electrical Eng. & Systems 2026-04-07 Fuxiang Tao , Dongwei Li , Shuning Tang , Xuri Ge , Wei Ma , Anna Esposito , Alessandro Vinciarelli

Accurate evaluation of Parkinsons disease (PD) severity is essential for effective clinical management and intervention development. Despite the proposal of several gesture based PD recognition systems, including those using the finger…

Computer Vision and Pattern Recognition · Computer Science 2025-11-12 Abu Saleh Musa Miah , Najmul Hassan , Md Maruf Al Hossain , Yuichi Okuyama , Jungpil Shin

Dementia is a progressive cognitive syndrome with Alzheimer's disease (AD) as the leading cause. Conversation-based AD detection offers a cost-effective alternative to clinical methods, as language dysfunction is an early biomarker of AD.…

Computation and Language · Computer Science 2025-02-27 Arezo Shakeri , Mina Farmanbar , Krisztian Balog

Parkinson's Disease(PD) is one of the major nervous system disorders that affect people over 60. PD can cause cognitive impairments. In this work, we explore various approaches to identify Parkinson's using Magnetic Resonance (MR) T1 images…

Image and Video Processing · Electrical Eng. & Systems 2020-07-03 Tahjid Ashfaque Mostafa , Irene Cheng

Early and accessible detection of Alzheimer's disease (AD) remains a major challenge, as current diagnostic methods often rely on costly and invasive biomarkers. Speech and language analysis has emerged as a promising non-invasive and…

Audio and Speech Processing · Electrical Eng. & Systems 2026-03-06 Franziska Braun , Christopher Witzl , Florian Hönig , Elmar Nöth , Tobias Bocklet , Korbinian Riedhammer

In this work, we use a deep learning framework for simultaneous classification and regression of Parkinson disease diagnosis based on MR-Images and personal information (i.e. age, gender). We intend to facilitate and increase the confidence…

Computer Vision and Pattern Recognition · Computer Science 2018-06-15 Soheil Esmaeilzadeh , Yao Yang , Ehsan Adeli

Discriminating between Parkinson's Disease (PD) and Progressive Supranuclear Palsy (PSP) is difficult due to overlapping symptoms, especially early on. Saccades (rapid conjugate eye movements between fixation points) are affected by both…

Quantitative Methods · Quantitative Biology 2024-07-25 Salil B Patel , Oliver B Bredemeyer , James J FitzGerald , Chrystalina A Antoniades

Large audio and language models have recently demonstrated zero-shot reasoning capabilities across various domains. However, it remains unclear how the form of audio input, whether handcrafted acoustic features extracted from speech or the…

Sound · Computer Science 2026-05-26 Muhammad Ashad Kabir , Sirajam Munira