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Eye movements can reveal early signs of neurodegeneration, including those associated with Parkinson's Disease (PD). This work investigates the utility of a set of gaze-based features for the automatic screening of PD from different visual…

Neurons and Cognition · Quantitative Biology 2025-09-03 Maria F. Alcala-Durand , J. Camilo Puerta-Acevedo , Julián D. Arias-Londoño , Juan I. Godino-Llorente

The assessment of Parkinson's disease (PD) poses a significant challenge as it is influenced by various factors which lead to a complex and fluctuating symptom manifestation. Thus, a frequent and objective PD assessment is highly valuable…

Autism spectrum disorder (ASD) can be defined as a neurodevelopmental disorder that affects how children interact, communicate and socialize with others. This disorder can occur in a broad spectrum of symptoms, with varying effects and…

Machine Learning · Computer Science 2021-10-08 Vikram Ramesh , Rida Assaf

In recent years, there are many research cases for the diagnosis of Parkinson's disease (PD) with the brain magnetic resonance imaging (MRI) by utilizing the traditional unsupervised machine learning methods and the supervised deep learning…

Image and Video Processing · Electrical Eng. & Systems 2020-03-11 Xiaobo Zhang , Donghai Zhai , Yan Yang , Yiling Zhang , Chunlin Wang

Parkinson's Disease (PD) is the second most common neurodegenerative disorder. The existing assessment method for PD is usually the Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS-UPDRS) to assess the severity of…

Computer Vision and Pattern Recognition · Computer Science 2024-04-03 Xiang Xiang , Zihan Zhang , Jing Ma , Yao Deng

PCA is a classical statistical technique whose simplicity and maturity has seen it find widespread use as an anomaly detection technique. However, it is limited in this regard by being sensitive to gross perturbations of the input, and by…

Machine Learning · Computer Science 2017-08-01 Raghavendra Chalapathy , Aditya Krishna Menon , Sanjay Chawla

Characterising the heterogeneous presentation of Parkinson's disease (PD) requires integrating biological and clinical markers within a unified predictive framework. While multimodal data provide complementary information, many existing…

Machine Learning · Computer Science 2026-01-05 Dristi Datta , Tanmoy Debnath , Minh Chau , Manoranjan Paul , Gourab Adhikary , Md Geaur Rahman

Principal Component Analysis (PCA) has been widely used for dimensionality reduction and feature extraction. Robust PCA (RPCA), under different robust distance metrics, such as l1-norm and l2, p-norm, can deal with noise or outliers to some…

Machine Learning · Computer Science 2021-06-29 Zhao Kang , Hongfei Liu , Jiangxin Li , Xiaofeng Zhu , Ling Tian

Early detection of exacerbations in asthma and chronic obstructive pulmonary disease (COPD) is important for timely intervention. Speech has emerged as a promising tool for continuous, non-invasive respiratory disease monitoring. However,…

Sound · Computer Science 2026-05-19 Yuyang Yan , Sami O. Simons , Visara Urovi

A promising approach for steering auditory attention in complex listening environments relies on Auditory Attention Decoding (AAD), which aim to identify the attended speech stream in a multiple speaker scenario from neural recordings.…

Background: Subtle changes in spontaneous language production are among the earliest indicators of cognitive decline. Identifying linguistically interpretable markers of dementia can support transparent and clinically grounded screening…

Computation and Language · Computer Science 2026-02-12 Artsvik Avetisyan , Sachin Kumar

Early detection of dementia is critical for timely medical intervention and improved patient outcomes. Neuropsychological tests are widely used for cognitive assessment but have traditionally relied on manual scoring. Automatic dementia…

Machine Learning · Computer Science 2025-07-15 Liming Wang , Saurabhchand Bhati , Cody Karjadi , Rhoda Au , James Glass

Alzheimer's disease (AD) is a progressive neurodegenerative disorder that leads to irreversible cognitive decline in memory and communication. Early detection of AD through speech analysis is crucial for delaying disease progression.…

Sound · Computer Science 2026-02-09 Yifan Gao , Long Guo , Hong Liu

Speech, language, and communication deficits are present in most neurodegenerative syndromes. They enable the early detection, diagnosis, treatment planning, and monitoring of neurocognitive disease progression as part of traditional…

Computation and Language · Computer Science 2023-12-07 Charalambos Themistocleous , Kyrana Tsapkini , Dimitrios Kokkinakis

Parkinson's Disease (PD) is characterized by disorders in motor function such as freezing of gait, rest tremor, rigidity, and slowed and hyposcaled movements. Medication with dopaminergic medication may alleviate those motor symptoms,…

Computer Vision and Pattern Recognition · Computer Science 2018-08-09 Terry Taewoong Um , Franz Michael Josef Pfister , Daniel Christian Pichler , Satoshi Endo , Muriel Lang , Sandra Hirche , Urban Fietzek , Dana Kulić

Multiscale modelling presents a multifaceted perspective into understanding the mechanisms of the brain and how neurodegenerative disorders like Parkinson's disease (PD) manifest and evolve over time. In this study, we propose a novel…

Neurons and Cognition · Quantitative Biology 2025-09-18 Aaron Herrera , Hina Shaheen

Respiratory diseases remain major global health challenges, and traditional auscultation is often limited by subjectivity, environmental noise, and inter-clinician variability. This study presents an explainable multimodal deep learning…

Sound · Computer Science 2025-12-02 S M Asiful Islam Saky , Md Rashidul Islam , Md Saiful Arefin , Shahaba Alam

Unsupervised learned representations of polysemous words generate a large of pseudo multi senses since unsupervised methods are overly sensitive to contextual variations. In this paper, we address the pseudo multi-sense detection for word…

Computation and Language · Computer Science 2018-03-06 Haoyue Shi , Yuqi Sun , Junfeng Hu

Speech translation has traditionally been approached through cascaded models consisting of a speech recognizer trained on a corpus of transcribed speech, and a machine translation system trained on parallel texts. Several recent works have…

Computation and Language · Computer Science 2019-04-16 Matthias Sperber , Graham Neubig , Jan Niehues , Alex Waibel

In this paper, we explore the task of mapping spoken language utterances to one of thousands of natural language understanding domains in intelligent personal digital assistants (IPDAs). This scenario is observed for many mainstream IPDAs…

Computation and Language · Computer Science 2018-04-24 Young-Bum Kim , Dongchan Kim , Anjishnu Kumar , Ruhi Sarikaya
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