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This paper presents a disease-severity-structured epidemic model with treatment necessary only to severe infective individuals to discuss the effect of the treatment capacity on the disease transmission. It is shown that a backward…

Populations and Evolution · Quantitative Biology 2021-10-05 Hiromu Gion , Yasuhisa Saito

In this paper, we propose an SIR spread model in a population network coupled with an infrastructure network that has a pathogen spreading in it. We develop a threshold condition to characterize the monotonicity and peak time of a weighted…

Systems and Control · Electrical Eng. & Systems 2026-04-08 José I. Caiza , Junjie Qin , Philip E. Paré

The initial phase of an epidemic is often characterized by an exponential increase in the number of infected individuals. In this paper, we predict the exponential spreading rate of an epidemic on a complex network. We first find an…

Physics and Society · Physics 2025-04-21 Samuel Cure , Florian G. Pflug , Simone Pigolotti

Understanding how age-specific social contact patterns and susceptibility influence infectious disease transmission is crucial for accurate epidemic modeling. This study presents an eigenvector-based sensitivity analysis framework to…

Populations and Evolution · Quantitative Biology 2025-11-21 Evans Kiptoo Korir , Zsolt Vizi

Macro-level modeling is still the dominant approach in many demographic applications because of its simplicity. Individual-level models, on the other hand, provide a more comprehensive understanding of observed patterns; however, their…

Applications · Statistics 2023-12-14 Daniel Ciganda , Nicolas Todd

We discuss how the presence of a large set of asymptomatic infectives changes our estimate of the COVID-19 basic reproduction number, also known as $R_0$.

Populations and Evolution · Quantitative Biology 2020-04-14 Giuseppe Gaeta

The current survey paper concerns stochastic mathematical models for the spread of infectious diseases. It starts with the simplest setting of a homogeneous population in which a transmittable disease spreads during a short outbreak.…

Applications · Statistics 2018-01-30 Tom Britton

The time-varying effective reproduction number $R_t$ is a widely used indicator of transmission dynamics during infectious disease outbreaks. Timely estimates of $R_t$ can be obtained from observations close to the original date of…

Methodology · Statistics 2024-07-15 Adrian Lison , Sam Abbott , Jana Huisman , Tanja Stadler

We consider an epidemiological SIR model and a positive threshold $M$. Using a parametric expression for the solution curve of the SIR model and the Lambert W function, we establish necessary and sufficient conditions on the basic…

Optimization and Control · Mathematics 2021-07-09 Andrés David Báez-Sánchez , Nara Bobko

A very large class of ODE epidemic models (2.2) discussed in this paper enjoys the property of admitting also an integral renewal formulation, with respect to an "age of infection kernel" a(t) which has a matrix exponential form (3.2). We…

Populations and Evolution · Quantitative Biology 2023-07-12 Florin Avram , Rim Adenane , Dan Goreac , Andrei Halanay

Modeling the spread of COVID-19 is crucial for informing public health policy. All models for COVID-19 epidemiology rely on parameters describing the dynamics of the infection process. The meanings of epidemiological parameters like R_0,…

Other Quantitative Biology · Quantitative Biology 2020-07-13 Yinon M. Bar-On , Ron Sender , Avi I. Flamholz , Rob Phillips , Ron Milo

I discuss the so-called SuperSpreader epidemic, for which SARS is the canonical examples (and, perhaps, MERS will be another). I use simulation by an agent-based model as well as the mathematics of multi-type branching-processes to…

Populations and Evolution · Quantitative Biology 2013-08-30 W. David Wick

Rabies remains a pressing global public health issue, demanding effective modeling and control strategies. This study focused on developing a mathematical model using ordinary differential equations (ODEs) to estimate parameters and assess…

Populations and Evolution · Quantitative Biology 2024-10-22 Mfano Charles , Sayoki G. Mfinanga , G. A. Lyakurwa , Delfim F. M. Torres , Verdiana G. Masanja

With a single circulating vector-borne virus, the basic reproduction number incorporates contributions from tick-to-tick (co-feeding), tick-to-host and host-to-tick transmission routes. With two different circulating vector-borne viral…

In most models of the spread of disease over contact networks it is assumed that the probabilities per unit time of disease transmission and recovery from disease are constant, implying exponential distributions of the time intervals for…

Physics and Society · Physics 2010-07-23 Brian Karrer , M. E. J. Newman

This paper is concerned with stochastic SIR and SEIR epidemic models on random networks in which individuals may rewire away from infected neighbors at some rate $\omega$ (and reconnect to non-infectious individuals with probability…

Populations and Evolution · Quantitative Biology 2016-11-15 Tom Britton , David Juher , Joan Saldana

We derive an analytical expression for the critical infection rate r_c of the susceptible-infectious-susceptible (SIS) disease spreading model on random networks. To obtain r_c, we first calculate the probability of reinfection, pi, defined…

Disordered Systems and Neural Networks · Physics 2010-07-16 Roni Parshani , Shai Carmi , Shlomo Havlin

In this paper, we propose a realistic mathematical model taking into account the mutual interference among the interacting populations. This model attempts to describe the control (vaccination) function as a function of the number of…

Neural and Evolutionary Computing · Computer Science 2016-11-18 V. Sree Hari Rao , M. Naresh Kumar

Many studies have proposed a relationship between COVID-19 transmissibility and ambient pollution levels. However, a major limitation in establishing such associations is to adequately account for complex disease dynamics, influenced by…

Populations and Evolution · Quantitative Biology 2021-09-07 Ognjen Milicevic , Igor Salom , Andjela Rodic , Sofija Markovic , Marko Tumbas , Dusan Zigic , Magdalena Djordjevic , Marko Djordjevic

This article introduces epidemia, an R package for Bayesian, regression-oriented modeling of infectious diseases. The implemented models define a likelihood for all observed data while also explicitly modeling transmission dynamics: an…

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