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The effective reproduction number, R(t), is a central point in the study of infectious diseases. It establishes in an explicit way the extent of an epidemic spread process in a population. The current estimation methods for the time…

Populations and Evolution · Quantitative Biology 2021-02-26 D. C. P. Jorge , J. F. Oliveira , J. G. V. Miranda , R. F. S. Andrade , S. T. R. Pinho

For nearly a century, the initial reproduction number (R0) has been used as a one number summary to compare outbreaks of infectious disease, yet there is no `standard' estimator for R0. Difficulties in estimating R0 arise both from how a…

Populations and Evolution · Quantitative Biology 2020-03-25 Shannon Gallagher , Andersen Chang , William F. Eddy

In the real world, many complex systems interact with other systems. In addition, the intra- or inter-systems for the spread of information about infectious diseases and the transmission of infectious diseases are often not random, but with…

Physics and Society · Physics 2017-08-23 Junbo Jia , Zhen Jin , Xinchu Fu

Early in an infectious disease outbreak, timely and accurate estimation of the basic reproduction number ($R_0$) and the serial interval (SI) is critical for understanding transmission dynamics and informing public health responses. While…

Methodology · Statistics 2026-01-29 Tatiana Krikella , Jane M. Heffernan , Hanna Jankowski

An approach to estimate the influence of the treatment-type controls on the basic reproduction number, R 0 , is proposed and elaborated. The presented approach allows one to estimate the effect of a given treatment strategy or to compare a…

Populations and Evolution · Quantitative Biology 2023-05-30 Dmitry Gromov , Ingo Bulla , Ethan Obie Romero-Severson

Plant diseases often cause serious yield losses in agriculture. A pathogen's reproductive fitness can be quantified by the basic reproductive number, R0. Since pathogen transmission between host plants depends on the spatial separation…

Populations and Evolution · Quantitative Biology 2014-10-03 Alexey Mikaberidze , Christopher C. Mundt , Sebastian Bonhoeffer

Branching processes are widely used to model evolutionary and population dynamics as well as the spread of infectious diseases. To characterize the dynamics of their growth or spread, the basic reproduction number $R_0$ has received…

Populations and Evolution · Quantitative Biology 2021-09-02 Johannes Pausch , Rosalba Garcia-Millan , Gunnar Pruessner

A pulse vaccination SIR model with periodic infection rate $\beta (t)$ have been proposed and studied. The basic reproductive number $R_0$ is defined. The dynamical behaviors of the model are analyzed with the help of persistence,…

Chaotic Dynamics · Physics 2009-05-29 Zhen Jin , Mainul Haque , Quanxing Liu

We consider a stochastic model of infection spread on the complete graph on $N$ vertices incorporating dynamic partnerships, which we assume to be monogamous. This can be seen as a variation on the contact process in which some form of edge…

Probability · Mathematics 2016-06-23 Eric Foxall , Roderick Edwards , P. van den Driessche

Real epidemic spreading networks often composed of several kinds of networks interconnected with each other, and the interrelated networks have the different topologies and epidemic dynamics. Moreover, most human diseases are derived from…

Physics and Society · Physics 2017-06-21 Zhongpu Xu , Xinchu Fu

The reproduction number of deterministic models is an essential quantity to predict whether an epidemic will spread or die out. Thresholds for disease extinction contribute crucial knowledge on disease control, elimination, and mitigation…

Populations and Evolution · Quantitative Biology 2013-08-08 Ling Xue , Caterina Scoglio

A great issue of discussion of an infectious disease is its basic reproduction number R0, which provides an estimation of the contagiousness of the disease. When R0 > 1, the disease spread will potentially lead to an outbreak, such that of…

Populations and Evolution · Quantitative Biology 2021-01-18 Dimitrios G. Patsatzis

During infectious disease outbreaks, estimates of time-varying pathogen transmissibility, such as the instantaneous reproduction number R(t) or epidemic growth rate r(t), are used to inform decision-making by public health authorities. For…

Populations and Evolution · Quantitative Biology 2024-09-30 Cathal Mills , Tarek Alrefae , William S. Hart , Moritz U. G. Kraemer , Kris V. Parag , Robin N. Thompson , Christl A. Donnelly , Ben Lambert

In this work, we revisit the basic reproduction rate $\mathcal{R}_{0}$ definition for analysis of epidemic-non-epidemic phases describing the dynamics of the discrete stochastic version of the epidemic $SIR$ model based on the Master…

Biological Physics · Physics 2007-05-23 O. E. Aiello , M. A. A. da Silva

We consider a family of periodic SEIRS epidemic models with a fairly general incidence rate and it is shown the basic reproduction number determines the global dynamics of the models and it is a threshold parameter for persistence.…

Dynamical Systems · Mathematics 2017-04-05 Eric Ávila-Vales , Erika Rivero-Esquivel , Gerardo García-Almeida

We study a multitype SIR epidemic model where individuals are categorized into different types, and where infection spread is characterized by a next-generation matrix $M=\{m_{ij}\}$ with community fractions $\{\pi_j\}$ for the different…

Populations and Evolution · Quantitative Biology 2026-03-10 Andrea Bizzotto , Frank Ball , Tom Britton

We develop a multi-patch and multi-group model that captures the dynamics of an infectious disease when the host is structured into an arbitrary number of groups and interacts into an arbitrary number of patches where the infection takes…

Populations and Evolution · Quantitative Biology 2017-11-23 Derdei Bichara , Abderrahman Iggidr

Recent evidences show that individuals who recovered from COVID-19 can be reinfected. However, this phenomenon has rarely been studied using mathematical models. In this paper, we propose a SEIRE epidemic model to describe the spread of the…

Populations and Evolution · Quantitative Biology 2022-05-17 Shaoli Wang , Tengfei Wang , Ya-nen Qi , Fei Xu

A general stochastic model for susceptible -> infective -> recovered (SIR) epidemics in non homogeneous populations is considered. The heterogeneity is a very important aspect here since it allows more realistic but also more complex…

Populations and Evolution · Quantitative Biology 2020-08-13 Zeynep Gökçe İşlier , Wolfgang Hörmann , Refik Güllü

The duration, type and structure of connections between individuals in real-world populations play a crucial role in how diseases invade and spread. Here, we incorporate the aforementioned heterogeneities into a model by considering a…

Physics and Society · Physics 2018-04-05 Rosanna C Barnard , Istvan Z Kiss , Luc Berthouze , Joel C Miller