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The basic reproduction number R0 is a concept which originated in population dynamics, mathematical epidemiology, and ecology and is closely related to the mean number of children in branching processes.We offer below three new…

Populations and Evolution · Quantitative Biology 2023-11-30 Florin Avram , Rim Adenane , Lasko Basnarkov , Matthew Johnston

A social (sexual) network is modeled by an extension of the configuration model to the situation where edges have weights, e.g. reflecting the number of sex-contacts between the individuals. An epidemic model is defined on the network such…

Probability · Mathematics 2011-12-21 Tom Britton , David Lindenstrand

The basic and effective reproduction numbers are widely used metrics for characterizing the dynamics of infectious disease epidemics. However, the interpretation of these numbers is based on the assumption of homogeneous mixing and may not…

Populations and Evolution · Quantitative Biology 2026-03-24 Zahra Ghadiri , Jari Saramäki , Takayuki Hiraoka

Many infectious diseases can lead to re-infection. We examined the relationship between the prevalence of repeat infection and the basic reproductive number (R0). First we solved a generic, deterministic compartmental model of re-infection…

Populations and Evolution · Quantitative Biology 2019-03-15 Joshua Feldman , Sharmistha Mishra

Analytical expressions for the basic reproduction number, R0, have been obtained in the past for a wide variety of mathematical models for infectious disease spread, along with expressions for the expected final size of an outbreak.…

Populations and Evolution · Quantitative Biology 2018-12-18 Sherry Towers , Linda J. S. Allen , Fred Brauer , Baltazar Espinoza

The time-dependent reproduction number Rt can be used to track pathogen transmission and to assess the efficacy of interventions. This quantity can be estimated by fitting renewal equation models to time series of infectious disease case…

Populations and Evolution · Quantitative Biology 2025-01-30 Ioana Bouros , Robin Thompson , David Gavaghan , Ben Lambert

The basic reproduction number, $R_0$, is a well-known quantifier of epidemic spread. However, a class of existing methods for estimating $R_0$ from incidence data early in the epidemic can lead to an over-estimation of this quantity. In…

Populations and Evolution · Quantitative Biology 2024-03-27 Wajid Ali , Christopher E. Overton , Robert R. Wilkinson , Kieran J. Sharkey

We study the Suscectible-Infected-Recovered-Susceptible (SIRS) epidemic model on deterministic networks. For connected but otherwise general interaction patterns and heterogeneous recovery and loss-of-immunity rates, we identify a…

Systems and Control · Electrical Eng. & Systems 2026-04-24 Giulia Gatti , Giacomo Como

A wide range of infectious diseases are both vertically and horizontally transmitted. Such diseases are spatially transmitted via multiple species in heterogeneous environments, typically described by complex meta-population models. The…

Populations and Evolution · Quantitative Biology 2013-03-05 Ling Xue , Caterina Scoglio

The basic reproduction number ($R_0$) is a threshold parameter for disease extinction or survival in isolated populations. However no human population is fully isolated from other human or animal populations. We use compartmental models to…

Populations and Evolution · Quantitative Biology 2018-09-05 Angus McLure , Kathryn Glass

This paper proposes a structural econometric approach to estimating the basic reproduction number ($\mathcal{R}_{0}$) of Covid-19. This approach identifies $\mathcal{R}_{0}$ in a panel regression model by filtering out the effects of…

Econometrics · Economics 2023-09-19 Ida Johnsson , M. Hashem Pesaran , Cynthia Fan Yang

Since the last century, deterministic compartmental models have emerged as powerful tools to predict and control epidemic outbreaks, in many cases helping to mitigate their impacts. A key quantity for these models is the so-called Basic…

Populations and Evolution · Quantitative Biology 2022-11-03 Àlex Giménez-Romero , Rosa Flaquer-Galmés , Manuel A. Matias

As widely known, the basic reproduction number plays a key role in weighing birth/infection and death/recovery processes in several models of population dynamics. In this general setting, its characterization as the spectral radius of next…

Numerical Analysis · Mathematics 2020-04-29 Dimitri Breda , Francesco Florian , Jordi Ripoll , Rossana Vermiglio

In epidemiological modelings, the spectral radius of the next generation matrix evaluated at the trivial equilibrium was considered as the basic reproduction number. Also, the global stability of the trivial equilibrium point was determined…

Populations and Evolution · Quantitative Biology 2020-06-15 Hyun Mo Yang

Reproduction numbers are widely used for the estimation and prediction of epidemic spreading processes over networks. However, reproduction numbers do not enable estimation and prediction in individual communities within networks, and they…

Systems and Control · Electrical Eng. & Systems 2025-06-23 Baike She , Philip E. Paré , Matthew Hale

The effect of diffusion rates on the basic reproduction number of a general compartmental reaction-diffusion epidemic model in a heterogeneous environment is considered. It is shown when the diffusion rates tend to zero, the limit of the…

Dynamical Systems · Mathematics 2019-09-24 Shanshan Chen , Junping Shi

Early estimates of the transmission potential of emerging and re-emerging infections are increasingly used to inform public health authorities on the level of risk posed by outbreaks. Existing methods to estimate the reproduction number…

Quantitative Methods · Quantitative Biology 2016-10-10 Gerardo Chowell , Cécile Viboud , Lone Simonsen , Seyed Moghadas

Due to its ability to summarise 'real-time' epidemic behaviour, the time-dependent reproduction number, Rt, is a useful metric for tracking pathogen transmission and quantifying the effects of interventions during infectious disease…

Populations and Evolution · Quantitative Biology 2026-03-12 Ioana Bouros , Robin Thompson , David Gavaghan , Ben Lambert

Petri Nets are an increasingly used modeling framework for the spread of disease across populations or within an individual. For example, the Susceptible-Infectious-Recovered (SIR) compartment model is foundational for population…

Other Quantitative Biology · Quantitative Biology 2025-07-02 Trevor Reckell , Bright Kwaku Manu , Beckett Sterner , Petar Jevtić , Reggie Davidrajuh

This is a pedagogical paper on estimating the number of people that can be infected by one infectious person during an epidemic outbreak, known as the reproduction number. Knowing the number is crucial for developing policy responses. There…

Populations and Evolution · Quantitative Biology 2020-06-30 H. Susanto , V. R. Tjahjono , A. Hasan , M. F. Kasim , N. Nuraini , E. R. M. Putri , R. Kusdiantara , H. Kurniawan