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Background: RETFound, a self-supervised, retina-specific foundation model (FM), showed potential in downstream applications. However, its comparative performance with traditional deep learning (DL) models remains incompletely understood.…

Automated medical diagnosis through image-based neural networks has increased in popularity and matured over years. Nevertheless, it is confined by the scarcity of medical images and the expensive labor annotation costs. Self-Supervised…

Computer Vision and Pattern Recognition · Computer Science 2024-04-17 Luffina C. Huang , Darren J. Chiu , Manish Mehta

Recent progress in self-supervised (SSL) visual representation learning has led to the development of several different proposed frameworks that rely on augmentations of images but use different loss functions. However, there are few…

Machine Learning · Computer Science 2025-01-20 Kumar Krishna Agrawal , Arna Ghosh , Shagun Sodhani , Adam Oberman , Blake Richards

Current deep learning models are mostly task specific and lack a user-friendly interface to operate. We present Meta-EyeFM, a multi-function foundation model that integrates a large language model (LLM) with vision foundation models (VFMs)…

The Vision-Language Foundation model is increasingly investigated in the fields of computer vision and natural language processing, yet its exploration in ophthalmology and broader medical applications remains limited. The challenge is the…

Computer Vision and Pattern Recognition · Computer Science 2024-08-20 Jiawei Du , Jia Guo , Weihang Zhang , Shengzhu Yang , Hanruo Liu , Huiqi Li , Ningli Wang

Optical coherence tomography (OCT) is a prevalent, interferometric, high-resolution imaging method with broad biomedical applications. Nonetheless, OCT images suffer from an artifact, called speckle which degrades the image quality. Digital…

We introduce OpenVLThinker, one of the first open-source large vision-language models (LVLMs) to exhibit sophisticated chain-of-thought reasoning, achieving notable performance gains on challenging visual reasoning tasks. While text-based…

Computer Vision and Pattern Recognition · Computer Science 2025-11-12 Yihe Deng , Hritik Bansal , Fan Yin , Nanyun Peng , Wei Wang , Kai-Wei Chang

There is substantial interest in developing artificial intelligence systems to support radiologists across tasks ranging from segmentation to report generation. Existing computed tomography (CT) foundation models have largely focused on…

Computer Vision and Pattern Recognition · Computer Science 2026-04-07 Rubén Moreno-Aguado , Alba Magallón , Victor Moreno , Yingying Fang , Guang Yang

Advances in deep learning are re-defining how visual data is processed and understand by the machines. Vision Transformers (ViTs) have recently demonstrated prominent performance in computer vision related tasks. However, their performance…

Foundation models are large-scale versatile systems trained on vast quantities of diverse data to learn generalizable representations. Their adaptability with minimal fine-tuning makes them particularly promising for medical imaging, where…

Image and Video Processing · Electrical Eng. & Systems 2025-03-20 Lucie Berger , Mathieu Lamard , Philippe Zhang , Laurent Borderie , Alexandre Le Guilcher , Pascale Massin , Béatrice Cochener , Gwenolé Quellec , Sarah Matta

Optical coherence tomography (OCT) helps ophthalmologists assess macular edema, accumulation of fluids, and lesions at microscopic resolution. Quantification of retinal fluids is necessary for OCT-guided treatment management, which relies…

Image and Video Processing · Electrical Eng. & Systems 2022-12-15 Reza Rasti , Armin Biglari , Mohammad Rezapourian , Ziyun Yang , Sina Farsiu

Vision-language models (VLMs) have shown remarkable abilities by integrating large language models with visual inputs. However, they often fail to utilize visual evidence adequately, either depending on linguistic priors in vision-centric…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Xiaojun Guo , Runyu Zhou , Yifei Wang , Qi Zhang , Chenheng Zhang , Stefanie Jegelka , Xiaohan Wang , Jiajun Chai , Guojun Yin , Wei Lin , Yisen Wang

Diabetic retinopathy (DR) is a leading cause of vision loss, requiring early and accurate assessment to prevent irreversible damage. Spectral Domain Optical Coherence Tomography (SD-OCT) enables high-resolution retinal imaging, but…

Image and Video Processing · Electrical Eng. & Systems 2025-07-15 S. Chen , D. Ma , M. Raviselvan , S. Sundaramoorthy , K. Popuri , M. J. Ju , M. V. Sarunic , D. Ratra , M. F. Beg

Self-supervised learning (SSL) has emerged as a powerful technique for improving the efficiency and effectiveness of deep learning models. Contrastive methods are a prominent family of SSL that extract similar representations of two…

Semi-supervised learning (SSL) leverages abundant unlabeled data alongside limited labeled data to enhance learning. As vision foundation models (VFMs) increasingly serve as the backbone of vision applications, it remains unclear how SSL…

Machine Learning · Computer Science 2025-11-06 Ping Zhang , Zheda Mai , Quang-Huy Nguyen , Wei-Lun Chao

Artificial Intelligence in medicine is traditionally limited by the lack of massive training datasets. Foundation models, pre-trained models that can be adapted to downstream tasks with small datasets, could alleviate this problem.…

Computer Vision and Pattern Recognition · Computer Science 2024-09-24 Justin Engelmann , Miguel O. Bernabeu

Optical coherence tomography (OCT) is widely used for diagnosing and monitoring retinal diseases, such as age-related macular degeneration (AMD). The segmentation of biomarkers such as layers and lesions is essential for patient diagnosis…

Computer Vision and Pattern Recognition · Computer Science 2025-09-26 Botond Fazekas , Guilherme Aresta , Philipp Seeböck , Julia Mai , Ursula Schmidt-Erfurth , Hrvoje Bogunović

Deep learning has proven very promising for interpreting MRI in brain tumor diagnosis. However, deep learning models suffer from a scarcity of brain MRI datasets for effective training. Self-supervised learning (SSL) models provide…

Image and Video Processing · Electrical Eng. & Systems 2024-11-21 Meryem Altin Karagoz , O. Ufuk Nalbantoglu , Geoffrey C. Fox

Our objective is to evaluate the efficacy of methods that use deep learning (DL) for the automatic fine-grained segmentation of optical coherence tomography (OCT) images of the retina. OCT images from 10 patients with mild non-proliferative…

Computer Vision and Pattern Recognition · Computer Science 2018-01-31 Mike Pekala , Neil Joshi , David E. Freund , Neil M. Bressler , Delia Cabrera DeBuc , Philippe M Burlina

Clinicians spend a significant amount of time reviewing medical images and transcribing their findings regarding patient diagnosis, referral and treatment in text form. Vision-language models (VLMs), which automatically interpret images and…

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