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We propose a new deep learning approach for automatic detection and segmentation of fluid within retinal OCT images. The proposed framework utilizes both ResNet and Encoder-Decoder neural network architectures. When training the network, we…

Computer Vision and Pattern Recognition · Computer Science 2017-08-21 Dustin Morley , Hassan Foroosh , Saad Shaikh , Ulas Bagci

Optical Coherence Tomography (OCT) is a non-invasive imaging modality essential for diagnosing various eye diseases. Despite its clinical significance, developing OCT-based diagnostic tools faces challenges, such as limited public datasets,…

Computer Vision and Pattern Recognition · Computer Science 2025-01-30 Mohammadreza Saraei , Igor Kozak , Eung-Joo Lee

In this paper, we present a new approach for uncertainty-aware retinal layer segmentation in Optical Coherence Tomography (OCT) scans using probabilistic signed distance functions (SDF). Traditional pixel-wise and regression-based methods…

Image and Video Processing · Electrical Eng. & Systems 2024-12-09 Mohammad Mohaiminul Islam , Coen de Vente , Bart Liefers , Caroline Klaver , Erik J Bekkers , Clara I. Sánchez

Gloss-free sign language translation (SLT) is hindered by two key challenges: **inadequate sign representation** that fails to capture nuanced visual cues, and **sentence-level semantic misalignment** in current LLM-based methods, which…

Computer Vision and Pattern Recognition · Computer Science 2025-12-09 Zhi Rao , Yucheng Zhou , Benjia Zhou , Yiqing Huang , Sergio Escalera , Jun Wan

Retinal diseases are a leading cause of vision impairment and blindness, with timely diagnosis being critical for effective treatment. Optical Coherence Tomography (OCT) has become a standard imaging modality for retinal disease diagnosis,…

Image and Video Processing · Electrical Eng. & Systems 2025-10-06 Jilan Cheng , Guoli Long , Zeyu Zhang , Zhenjia Qi , Hanyu Wang , Libin Lu , Shuihua Wang , Yudong Zhang , Jin Hong

Conventional Fourier-domain Optical Coherence Tomography (FD-OCT) systems depend on resampling into wavenumber (k) domain to extract the depth profile. This either necessitates additional hardware resources or amplifies the existing…

Optics · Physics 2025-09-24 Maryam Viqar , Erdem Sahin , Elena Stoykova , Violeta Madjarova

Retinal optical coherence tomography (OCT) images provide crucial insights into the health of the posterior ocular segment. Therefore, the advancement of automated image analysis methods is imperative to equip clinicians and researchers…

Image and Video Processing · Electrical Eng. & Systems 2024-02-16 Jiahao Wang , Hong Peng , Shengchao Chen , Sufen Ren

Large vision foundation models have been widely adopted for retinal disease classification without systematic evidence justifying their parameter requirements. In the present work we address two critical questions: First, are large…

Image and Video Processing · Electrical Eng. & Systems 2025-12-01 David Isztl , Tahm Spitznagel , Gabor Mark Somfai , Rui Santos

With Transformers achieving outstanding performance on individual remote sensing (RS) tasks, we are now approaching the realization of a unified model that excels across multiple tasks through multi-task learning (MTL). Compared to…

Computer Vision and Pattern Recognition · Computer Science 2026-01-12 Qingyun Li , Shuran Ma , Junwei Luo , Yi Yu , Yue Zhou , Fengxiang Wang , Xudong Lu , Xiaoxing Wang , Xin He , Yushi Chen , Xue Yang

Inability to express the confidence level and detect unseen classes has limited the clinical implementation of artificial intelligence in the real-world. We developed a foundation model with uncertainty estimation (FMUE) to detect 11…

Image and Video Processing · Electrical Eng. & Systems 2024-06-26 Yuanyuan Peng , Aidi Lin , Meng Wang , Tian Lin , Ke Zou , Yinglin Cheng , Tingkun Shi , Xulong Liao , Lixia Feng , Zhen Liang , Xinjian Chen , Huazhu Fu , Haoyu Chen

Large language models (LLMs) have shown remarkable effectiveness across various domains, with data augmentation methods utilizing GPT for synthetic data generation becoming prevalent. However, the quality and utility of augmented data…

Computation and Language · Computer Science 2025-01-27 Zeao Tu , Xiangdi Meng , Yu He , Zihan Yao , Tianyu Qi , Jun Liu , Ming Li

Purpose: We proposed a deep convolutional neural network (CNN), named Retinal Fluid Segmentation Network (ReF-Net) to segment volumetric retinal fluid on optical coherence tomography (OCT) volume. Methods: 3 x 3-mm OCT scans were acquired…

Image and Video Processing · Electrical Eng. & Systems 2020-10-28 Yukun Guo , Tristan T. Hormel , Honglian Xiong , Jie Wang , Thomas S. Hwang , Yali Jia

Self-Supervised Learning (SSL) is at the core of training modern large machine learning models, providing a scheme for learning powerful representations that can be used in a variety of downstream tasks. However, SSL strategies must be…

High Energy Physics - Phenomenology · Physics 2025-02-26 Philip Harris , Michael Kagan , Jeffrey Krupa , Benedikt Maier , Nathaniel Woodward

In the world of medical diagnostics, the adoption of various deep learning techniques is quite common as well as effective, and its statement is equally true when it comes to implementing it into the retina Optical Coherence Tomography…

Image and Video Processing · Electrical Eng. & Systems 2022-03-03 Tasnim Sakib Apon , Mohammad Mahmudul Hasan , Abrar Islam , MD. Golam Rabiul Alam

Retinal foundation models aim to learn generalizable representations from diverse retinal images, facilitating label-efficient model adaptation across various ophthalmic tasks. Despite their success, current retinal foundation models are…

Computer Vision and Pattern Recognition · Computer Science 2024-08-13 Kai Yu , Yang Zhou , Yang Bai , Zhi Da Soh , Xinxing Xu , Rick Siow Mong Goh , Ching-Yu Cheng , Yong Liu

Semantic-rich features from Vision Foundation Models (VFMs) have been leveraged to enhance Latent Diffusion Models (LDMs). However, raw VFM features are typically high-dimensional and redundant, increasing the difficulty of learning and…

Computer Vision and Pattern Recognition · Computer Science 2026-05-15 Guanfang Dong , Luke Schultz , Negar Hassanpour , Chao Gao

Multimodal Large Language Models (MLLMs) have shown strong performance in document image tasks, especially Optical Character Recognition (OCR). However, they struggle with Document Image Machine Translation (DIMT), which requires handling…

Computation and Language · Computer Science 2025-07-14 Yupu Liang , Yaping Zhang , Zhiyang Zhang , Zhiyuan Chen , Yang Zhao , Lu Xiang , Chengqing Zong , Yu Zhou

Foundation models (FMs), powered by self-supervised learning (SSL), have redefined the capabilities of artificial intelligence, demonstrating exceptional performance in domains like natural language processing and computer vision. These…

Machine Learning · Computer Science 2025-06-23 Hamdi Altaheri , Fakhri Karray , Md. Milon Islam , S M Taslim Uddin Raju , Amir-Hossein Karimi

Supervised fine-tuning (SFT) plays a crucial role in adapting large language models (LLMs) to specific domains or tasks. However, as demonstrated by empirical experiments, the collected data inevitably contains noise in practical…

Computation and Language · Computer Science 2024-12-20 Junyu Luo , Xiao Luo , Kaize Ding , Jingyang Yuan , Zhiping Xiao , Ming Zhang

Retinal image matching plays a crucial role in monitoring disease progression and treatment response. However, datasets with matched keypoints between temporally separated pairs of images are not available in abundance to train…

Computer Vision and Pattern Recognition · Computer Science 2023-07-24 Sahar Almahfouz Nasser , Nihar Gupte , Amit Sethi