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Current fMRI foundation models primarily rely on a limited range of brain states and mismatched pretraining tasks, restricting their ability to learn generalized representations across diverse brain states. We present \textit{Brain-DiT}, a…

Computer Vision and Pattern Recognition · Computer Science 2026-04-15 Junfeng Xia , Wenhao Ye , Xuanye Pan , Xinke Shen , Mo Wang , Quanying Liu

In the big data era, integrating diverse data modalities poses significant challenges, particularly in complex fields like healthcare. This paper introduces a new process model for multimodal Data Fusion for Data Mining, integrating…

Artificial Intelligence · Computer Science 2024-06-04 David Restrepo , Chenwei Wu , Constanza Vásquez-Venegas , Luis Filipe Nakayama , Leo Anthony Celi , Diego M López

Foundation models in digital pathology use massive datasets to learn useful compact feature representations of complex histology images. However, there is limited transparency into what drives the correlation between dataset size and…

Resting-state functional magnetic resonance imaging (rs-fMRI) is a noninvasive technique pivotal for understanding human neural mechanisms of intricate cognitive processes. Most rs-fMRI studies compute a single static functional…

Neurons and Cognition · Quantitative Biology 2025-02-25 Bishal Thapaliya , Robyn Miller , Jiayu Chen , Yu-Ping Wang , Esra Akbas , Ram Sapkota , Bhaskar Ray , Pranav Suresh , Santosh Ghimire , Vince Calhoun , Jingyu Liu

While the shift toward unified foundation models has revolutionized many deep learning domains, sleep medicine remains largely restricted to task-specific models that focus on localized micro-structure features. These approaches often…

Artificial Intelligence · Computer Science 2026-02-10 Keondo Park , Younghoon Na , Yourim Choi , Hyunwoo Ryu , Hyun-Woo Shin , Hyung-Sin Kim

Multimodal learning enhances the perceptual capabilities of cognitive systems by integrating information from different sensory modalities. However, existing multimodal fusion research typically assumes static integration, not fully…

Neural and Evolutionary Computing · Computer Science 2025-05-16 Xiang He , Dongcheng Zhao , Yang Li , Qingqun Kong , Xin Yang , Yi Zeng

Human perception plays a vital role in forming beliefs and understanding reality. A deeper understanding of brain functionality will lead to the development of novel deep neural networks. In this work, we introduce a novel framework named…

Computer Vision and Pattern Recognition · Computer Science 2024-11-27 Xuan-Bac Nguyen , Xin Li , Pawan Sinha , Samee U. Khan , Khoa Luu

In neuroscience, functional brain connectivity describes the connectivity between brain regions that share functional properties. Neuroscientists often characterize it by a time series of covariance matrices between functional measurements…

Methodology · Statistics 2019-07-09 Zhenhua Lin , Dehan Kong , Qiang Sun

We present UNIPHY+, a unified physiological foundation model (physioFM) framework designed to enable continuous human health and diseases monitoring across care settings using ubiquitously obtainable physiological data. We propose novel…

Physiological signals are often corrupted by motion artifacts, baseline drift, and other low-SNR disturbances, which pose significant challenges for analysis. Additionally, these signals exhibit strong non-stationarity, with sharp peaks and…

Machine Learning · Computer Science 2025-10-21 Yanlong Chen , Mattia Orlandi , Pierangelo Maria Rapa , Simone Benatti , Luca Benini , Yawei Li

Recent neuroimaging studies that focus on predicting brain disorders via modern machine learning approaches commonly include a single modality and rely on supervised over-parameterized models.However, a single modality provides only a…

Recent advances in multimodal large language models (LLMs) have enabled unified reasoning across images, audio, and video, but extending such capability to brain imaging remains largely unexplored. Bridging this gap is essential to link…

Computation and Language · Computer Science 2026-05-15 Yuxiang Wei , Yanteng Zhang , Xi Xiao , Chengxuan Qian , Tianyang Wang , Vince D. Calhoun

Magnetic resonance imaging~(MRI) have played a crucial role in brain disease diagnosis, with which a range of computer-aided artificial intelligence methods have been proposed. However, the early explorations usually focus on the limited…

Computer Vision and Pattern Recognition · Computer Science 2023-09-14 Jiayu Lei , Lisong Dai , Haoyun Jiang , Chaoyi Wu , Xiaoman Zhang , Yao Zhang , Jiangchao Yao , Weidi Xie , Yanyong Zhang , Yuehua Li , Ya Zhang , Yanfeng Wang

Traditional functional connectivity based on functional magnetic resonance imaging (fMRI) can only capture pairwise interactions between brain regions. Hypergraphs, which reveal high-order relationships among multiple brain regions, have…

Neurons and Cognition · Quantitative Biology 2025-05-20 Wenqi Hu , Xuerui Su , Guanliang Li , Yidi Pan , Aijing Lin

With the increasing availability of diverse data types, particularly images and time series data from medical experiments, there is a growing demand for techniques designed to combine various modalities of data effectively. Our motivation…

Image and Video Processing · Electrical Eng. & Systems 2024-05-27 Ali Rasekh , Reza Heidari , Amir Hosein Haji Mohammad Rezaie , Parsa Sharifi Sedeh , Zahra Ahmadi , Prasenjit Mitra , Wolfgang Nejdl

Functional Magnetic Resonance Imaging (fMRI) is an imaging technique widely used to study human brain activity. fMRI signals in areas across the brain transiently synchronise and desynchronise their activity in a highly structured manner,…

Machine Learning · Computer Science 2025-08-12 Yiran Huang , Amirhossein Nouranizadeh , Christine Ahrends , Mengjia Xu

Functional magnetic resonance imaging (fMRI) is an indispensable tool in modern neuroscience, providing a non-invasive window into whole-brain dynamics at millimeter-scale spatial resolution. However, fMRI is constrained by issues such as…

Image and Video Processing · Electrical Eng. & Systems 2025-09-09 Yamin Li , Ange Lou , Ziyuan Xu , Shengchao Zhang , Shiyu Wang , Dario J. Englot , Soheil Kolouri , Daniel Moyer , Roza G. Bayrak , Catie Chang

In the fields of computer vision (CV) and remote sensing (RS), foundational models typically follow the "big data + large model parameters" paradigm. However, the application of this strategy in seismic data processing faces several…

Geophysics · Physics 2025-03-14 Xintong Dong , Wenshuo Yu , Jun Lin , Zhenbo Guo , Hongzhou Wang , Jianhao Yang

Pain is a complex and pervasive condition that affects a significant portion of the population. Accurate and consistent assessment is essential for individuals suffering from pain, as well as for developing effective management strategies…

Artificial Intelligence · Computer Science 2025-09-17 Stefanos Gkikas , Ioannis Kyprakis , Manolis Tsiknakis

Recent advances in large-scale pre-trained Electroencephalogram (EEG) models have shown great promise, driving progress in Brain-Computer Interfaces (BCIs) and healthcare applications. However, despite their success, many existing…

Machine Learning · Computer Science 2025-10-07 Konstantinos Barmpas , Na Lee , Yannis Panagakis , Dimitrios A. Adamos , Nikolaos Laskaris , Stefanos Zafeiriou
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