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An Ebola outbreak of unparalleled size is currently affecting several countries in West Africa, and international efforts to control the outbreak are underway. However, the efficacy of these interventions, and their likely impact on an…

Populations and Evolution · Quantitative Biology 2014-09-23 Caitlin M. Rivers , Eric T. Lofgren , Madhav Marathe , Stephen Eubank , Bryan L. Lewis

Dengue incidence forecasting using hybrid models has been surging in the data rich world. Hybridization of statistical time series forecasting models and machine learning models are explored for dengue forecasting with different degrees of…

Populations and Evolution · Quantitative Biology 2023-12-27 I. Ghosh , S. Gupta , S. Rana

Early estimates of the transmission potential of emerging and re-emerging infections are increasingly used to inform public health authorities on the level of risk posed by outbreaks. Existing methods to estimate the reproduction number…

Quantitative Methods · Quantitative Biology 2016-10-10 Gerardo Chowell , Cécile Viboud , Lone Simonsen , Seyed Moghadas

Accurate forecasts of the number of newly infected people during an epidemic are critical for making effective timely decisions. This paper addresses this challenge using the SIMLR model, which incorporates machine learning (ML) into the…

Machine Learning · Computer Science 2021-06-04 Roberto Vega , Leonardo Flores , Russell Greiner

Emerging in December 2019, the COVID-19 pandemic caused widespread health, economic, and social disruptions. Rapid global transmission overwhelmed healthcare systems, resulting in high infection rates, hospitalisations, and fatalities. To…

Populations and Evolution · Quantitative Biology 2025-10-08 Zacharias Komodromos , Kleanthis Malialis , Panayiotis Kolios

Epidemics-inspired techniques have received huge attention in recent years from the distributed systems and networking communities. These algorithms and protocols rely on probabilistic message replication and redundancy to ensure reliable…

Networking and Internet Architecture · Computer Science 2007-11-20 Salvatore Scellato , Cecilia Mascolo , Mirco Musolesi , Vito Latora

Forecasting the short-term spread of an ongoing disease outbreak is a formidable challenge due to the complexity of contributing factors, some of which can be characterized through interlinked, multi-modality variables such as…

Machine Learning · Computer Science 2024-04-11 Hongru Du , Jianan Zhao , Yang Zhao , Shaochong Xu , Xihong Lin , Yiran Chen , Lauren M. Gardner , Hao Frank Yang

Pandemic management requires that scientists rapidly formulate and analyze epidemiological models in order to forecast the spread of disease and the effects of mitigation strategies. Scientists must modify existing models and create novel…

Programming Languages · Computer Science 2022-10-12 Sophie Libkind , Andrew Baas , Micah Halter , Evan Patterson , James Fairbanks

Many applications in different domains produce large amount of time series data. Making accurate forecasting is critical for many decision makers. Various time series forecasting methods exist which use linear and nonlinear models…

Machine Learning · Computer Science 2019-07-19 Ümit Çavuş Büyükşahin , Şeyda Ertekin

In this paper, based on the Akaike information criterion, root mean square error and robustness coefficient, a rational evaluation of various epidemic models/methods, including seven empirical functions, four statistical inference methods…

Populations and Evolution · Quantitative Biology 2021-09-16 Wuyue Yang , Dongyan Zhang , Liangrong Peng , Changjing Zhuge , Liu Hong

This study presents a neural network-enhanced approach to modeling disease spread dynamics over time and space. Neural networks are used to estimate time-varying parameters, with two calibration methods explored: Approximate Bayesian…

Quantitative Methods · Quantitative Biology 2024-10-29 Randy L. Caga-anan

Stochastic epidemic models provide an interpretable probabilistic description of the spread of a disease through a population. Yet, fitting these models to partially observed data is a notoriously difficult task due to intractability of the…

Computation · Statistics 2022-10-21 Raphael Morsomme , Jason Xu

Epidemiological models can not only be used to forecast the course of a pandemic like COVID-19, but also to propose and design non-pharmaceutical interventions such as school and work closing. In general, the design of optimal policies…

Optimization and Control · Mathematics 2023-04-06 Jan-Hendrik Niemann , Samuel Uram , Sarah Wolf , Nataša Djurdjevac Conrad , Martin Weiser

Despite the recent development of methods dealing with partially observed epidemic dynamics (unobserved model coordinates, discrete and noisy outbreak data), limitations remain in practice, mainly related to the quantity of augmented data…

Applications · Statistics 2021-07-26 Romain Narci , Maud Delattre , Catherine Larédo , Elisabeta Vergu

Accurate demand forecasting is vital for ensuring reliable access to contraceptive products, supporting key processes like procurement, inventory, and distribution. However, forecasting contraceptive demand in developing countries presents…

Machine Learning · Computer Science 2025-03-10 Harsha Chamara Hewage , Bahman Rostami-Tabar , Aris Syntetos , Federico Liberatore , Glenn Milano

We introduce a new method for inference in stochastic epidemic models which uses recursive multinomial approximations to integrate over unobserved variables and thus circumvent likelihood intractability. The method is applicable to a class…

Methodology · Statistics 2021-02-24 Nick Whiteley , Lorenzo Rimella

Accurate epidemic forecasting plays a vital role for governments in developing effective prevention measures for suppressing epidemics. Most of the present spatio-temporal models cannot provide a general framework for stable, and accurate…

Machine Learning · Computer Science 2023-06-23 Junkai Mao , Yuexing Han , Bing Wang

Compartmental models have long served as important tools in mathematical epidemiology, with their usefulness highlighted by the recent COVID-19 pandemic. However, most of the classical models fail to account for certain features of this…

Dynamical Systems · Mathematics 2023-08-21 Monique Chyba , Taylor Klotz , Yuriy Mileyko , Corey Shanbrom

Epidemiologists use a variety of statistical algorithms for the early detection of outbreaks. The practical usefulness of such methods highly depends on the trade-off between the detection rate of outbreaks and the chances of raising a…

Machine Learning · Computer Science 2019-07-18 Moritz Kulessa , Eneldo Loza Mencía , Johannes Fürnkranz

We present EPITIME (EPidemic Integral models TIMe profile Explorer), a computational framework for the simulation of two classes of integral epidemic models: an age of infection model and an information dependent behavioural model. The…

Quantitative Methods · Quantitative Biology 2026-05-04 Bruno Buonomo , Eleonora Messina , Claudia Panico , Mario Pezzella , Gaetano Zanghirati