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We discuss estimation and inference of conditional treatment effects in regression discontinuity (RD) designs with multiple scores. In addition to local linear regressions and the minimax-optimal estimator more recently proposed by Imbens…

Econometrics · Economics 2025-06-10 Yiqi Liu , Yuan Qi

Infectious diseases on farms pose both public and animal health risks, so understanding how they spread between farms is crucial for developing disease control strategies to prevent future outbreaks. We develop novel Bayesian nonparametric…

Applications · Statistics 2021-08-24 R. G. Seymour , T. Kypraios , P. D. O'Neill , T. J. Hagenaars

Hepatitis C virus (HCV) infection is endemic in people who inject drugs (PWID), with prevalence estimates above 60 percent for PWID in the United States. Previous modeling studies suggest that direct acting antiviral (DAA) treatment can…

Populations and Evolution · Quantitative Biology 2019-03-06 Bilal Khan , Ian Duncan , Mohamad Saad , Daniel Schaefer , Ashly Jordan , Daniel Smith , Alan Neaigus , Don Des Jarlais , Holly Hagan , Kirk Dombrowski

In face of climate change and increasing urbanization, the predictive mosquito-borne diseases (MBD) transmission models require constant updates. Thus, is urgent to comprehend the driving forces of this non stationary behavior, observed…

Quantitative Methods · Quantitative Biology 2024-11-22 Marcio Maciel Bastos , Luiz Max Carvalho , Eduardo Correa Araujo , Flávio Codeço Coelho

The treatment of malaria is a global health challenge that stands to benefit from the widespread introduction of a vaccine for the disease. A method has been developed to create a live organism vaccine using the sporozoites (SPZ) of the…

In agriculture, molecular communication (MC) is envisioned as a framework to address critical challenges such as smart pest control. While conventional approaches mostly rely on synthetic plant protection products, posing high risks for the…

We present a study of the worldwide spread of a pandemic influenza and its possible containment at a global level taking into account all available information on air travel. We studied a metapopulation stochastic epidemic model on a global…

Other Quantitative Biology · Quantitative Biology 2007-05-23 Vittoria Colizza , Alain Barrat , Marc Barthelemy , Alain-Jacques Valleron , Alessandro Vespignani

Sequential decision-making under cost-sensitive tasks is prohibitively daunting, especially for the problem that has a significant impact on people's daily lives, such as malaria control, treatment recommendation. The main challenge faced…

Machine Learning · Computer Science 2021-05-06 Lixin Zou , Long Xia , Linfang Hou , Xiangyu Zhao , Dawei Yin

Malaria can be diagnosed by the presence of parasites and symptoms (usually fever) due to the parasites. In endemic areas, however, an individual may have fever attributable either to malaria or to other causes. Thus, the parasite level of…

Methodology · Statistics 2025-07-22 Zhaoyang Tian , Kun Liang , Pengfei Li

Many models of within-host malaria infection dynamics have been formulated since the pioneering work of Anderson et al. in 1989. Biologically, the goal of these models is to understand what governs the severity of infections, the patterns…

Analysis of PDEs · Mathematics 2022-02-18 Ramsès Djidjou-Demasse , Arnaud Ducrot , Nicole Mideo , Gaëtan Texier

Timely and robust influenza incidence forecasting is critical for public health decision-making. This paper presents MAESTRO (Multi-modal Adaptive Estimation for Temporal Respiratory Disease Outbreak), a novel, unified framework that…

Machine Learning · Computer Science 2025-09-22 Hong Liu , Kerui Cen , Yanxing Chen , Zige Liu , Dong Chen , Zifeng Yang , Chitin Hon

Malaria can be prevented, diagnosed, and treated; however, every year, there are more than 200 million cases and 200.000 preventable deaths. Malaria remains a pressing public health concern in low- and middle-income countries, especially in…

Machine Learning · Statistics 2023-03-20 África Periáñez , Andrew Trister , Madhav Nekkar , Ana Fernández del Río , Pedro L. Alonso

More than half of the world's population is exposed to the risk of mosquito-borne diseases, which leads to millions of cases and hundreds of thousands of deaths every year. Analyzing this type of data is often complex and poses several…

Methodology · Statistics 2025-07-14 Jessica Pavani , Fernando Andrés Quintana

Over 50% of the world population is at risk of mosquito-borne diseases. Female Ae. aegypti mosquito species transmit Zika, Dengue, and Chikungunya. The spread of these diseases correlate positively with the vector population, and this…

Populations and Evolution · Quantitative Biology 2019-11-28 Oladimeji Mudele , Fabio M. Bayer , Lucas Zanandrez , Alvaro E. Eiras , Paolo Gamba

Malaria transmission in Madagascar is highly heterogeneous, exhibiting spatial, seasonal and long-term trends. Previous efforts to map malaria risk in Madagascar used prevalence data from Malaria Indicator Surveys. These cross-sectional…

Background: Although the outbreak of human monkeypox (mpox) caused by the monkeypox virus (MPXV) has slowed down around the world, little is known about the short-term dynamics of this disease. This limited information highlights the…

Dynamical Systems · Mathematics 2024-12-12 Md. Azmir Ibne Islam , M H M Mubassir , Arindam Kumar Paul , Sharmin Sultana Shanta

Lung cancer is one of the major causes of death worldwide, and Vietnam is not an exception. This disease is the second most common type of cancer globally and the second most common cause of death in Vietnam, just after liver cancer, with…

Machine Learning · Computer Science 2025-04-14 Ngoc Hong Tran , Lan Kim Vien , Ngoc-Thao Thi Le

Although hyperthyroidism is a common disease, the pharmaceutical therapy is based on a trial-and-error approach. We extend a mathematical model of the pituitary-thyroid feedback loop such that the intake of one antithyroid agent, namely…

Systems and Control · Electrical Eng. & Systems 2023-08-01 Maylin Menzel , Tobias M. Wolff , Johannes W. Dietrich , Matthias A. Müller

Dengue transmission is shaped by the population dynamics of the Aedes aegypti mosquito, making vector control a central strategy for disease mitigation. The impact of interventions such as larvicide, adulticide, and breeding-site reduction…

Dynamical Systems · Mathematics 2026-05-13 Aram Vajdi , Lee W. Cohnstaedt , Caterina M. Scoglio , Heman Shakeri

Widespread application of insecticide remains the primary form of control for Chagas disease in Central America, despite only temporarily reducing domestic levels of the endemic vector Triatoma dimidiata and having little long-term impact.…