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Recent mosquito-borne outbreaks have revealed vulnerabilities in our abatement programmes, raising concerns about how abatement-districts should choose optimal future control strategies. Spatial dissemination of vector-borne disease is…

Populations and Evolution · Quantitative Biology 2025-12-10 Suman Bhowmick , Patrick Irwin , Kristina Lopez , Megan Lindsay Fritz , Rebecca Lee Smith

Background As more regions approach malaria elimination, understanding how different interventions interact to reduce transmission becomes critical. The Lake Kariba area of Southern Province, Zambia, is part of a multi-country elimination…

Malaria control strategies aiming at reducing disease transmission intensity may impact both oocyst intensity and infection prevalence in the mosquito vector. Thus far, mathematical models failed to identify a clear relationship between…

Statistics Theory · Mathematics 2011-02-24 Robin Genuer , Isabelle Morlais , Wilson Toussile

Many malaria-endemic areas experience seasonal fluctuations in case incidence as Anopheles mosquito and Plasmodium parasite life cycles respond to changing environmental conditions. While most existing maps of malaria seasonality use fixed…

Prevalence surveys are routinely used to monitor the effectiveness of mass drug administration (MDA) programmes for controlling neglected tropical diseases (NTDs). We propose a decay-adjusted spatio-temporal (DAST) model that explicitly…

Applications · Statistics 2026-04-13 Emanuele Giorgi , Claudio Fronterre , Peter J. Diggle

The Mekong Delta Region of Vietnam faces increasing dengue risks driven by urbanization, globalization, and climate change. This study introduces a probabilistic forecasting model for predicting dengue incidence and outbreaks with one to…

Falciparum malaria is a major parasitic disease causing widespread morbidity and mortality globally. Artemisinin derivatives---the most effective and widely-used antimalarials that have helped reduce the burden of malaria by 60% in some…

Neglected tropical diseases (NTD), particularly vector-borne diseases (VBD), account for a large proportion of the global disease burden, and their control faces several challenges including diminishing human and financial resources for…

Populations and Evolution · Quantitative Biology 2016-09-06 Swati DebRoy , Olivia Prosper , Austin Mishoe , Anuj Mubayi

Malaria is an infectious disease affecting a large population across the world, and interventions need to be efficiently applied to reduce the burden of malaria. We develop a framework to help policy-makers decide how to allocate limited…

Applications · Statistics 2020-03-12 Qian Guan , Brian J. Reich , Eric B. Laber

Antimalarial drugs are a powerful tool for malaria control and elimination. Artemisinin-based combination therapies (ACTs) can reduce transmission when widely distributed in a campaign setting. Modelling mass antimalarial campaigns can…

Populations and Evolution · Quantitative Biology 2015-04-01 Jaline Gerardin , Philip Eckhoff , Edward A. Wenger

Mass campaigns with antimalarial drugs are potentially a powerful tool for local elimination of malaria, yet current diagnostic technologies are insufficiently sensitive to identify all individuals who harbor infections. At the same time,…

Populations and Evolution · Quantitative Biology 2016-02-17 Jaline Gerardin , Caitlin A. Bever , Busiku Hamainza , John M. Miller , Philip A. Eckhoff , Edward A. Wenger

Malaria is a serious global health problem which is especially devastating to the developing world. Mosquitoes are the carriers of the parasite responsible for the disease, and hence malaria control programs focus on controlling mosquito…

Dynamical Systems · Mathematics 2016-06-17 Bhushan Kotnis , Joy Kuri

Geostatistical analysis of health data is increasingly used to model spatial variation in malaria prevalence, burden, and other metrics. Traditional inference methods for geostatistical modelling are notoriously computationally intensive,…

Applications · Statistics 2023-05-04 Spencer Wong , Jennifer A. Flegg , Nick Golding , Sevvandi Kandanaarachchi

Malaria is the leading cause of death globally, especially in sub-Saharan African countries claiming over 400,000 deaths globally each year, underscoring the critical need for continued efforts to combat this preventable and treatable…

The task of decision-making under uncertainty is daunting, especially for problems which have significant complexity. Healthcare policy makers across the globe are facing problems under challenging constraints, with limited tools to help…

Artificial Intelligence · Computer Science 2017-12-04 Oliver Bent , Sekou L. Remy , Stephen Roberts , Aisha Walcott-Bryant

Mosquitoes are a major vector for malaria, causing hundreds of thousands of deaths in the developing world each year. Not only is the prevention of mosquito bites of paramount importance to the reduction of malaria transmission cases, but…

Machine Learning · Statistics 2017-12-07 Yunpeng Li , Davide Zilli , Henry Chan , Ivan Kiskin , Marianne Sinka , Stephen Roberts , Kathy Willis

West Nile virus (WNV) is a mosquito-borne virus in the genus Flavivirus that circulates between mosquitoes and birds, whereas humans, equids, and other mammals are dead-end hosts. Since its emergence in Germany in 2018, the virus has spread…

Populations and Evolution · Quantitative Biology 2026-03-18 Pride Duve , Felix Gregor Sauer , Renke Lühken

The global spread of avian influenza A viruses in domestic birds is causing dramatic economic and social losses. Various mechanistic models have been developed in an attempt to better understand avian influenza transmission and to evaluate…

Quantitative Methods · Quantitative Biology 2023-03-02 Sébastien Lambert , Billy Bauzile , Amélie Mugnier , Benoit Durand , Timothée Vergne , Mathilde C Paul

Impact assessment of natural hazards requires the consideration of both extreme and non-extreme events. Extensive research has been conducted on the joint modeling of bulk and tail in univariate settings; however, the corresponding body of…

Methodology · Statistics 2026-03-31 Chenglei Hu , Ben Swallow , Daniela Castro-Camilo

Disease and pest control largely rely on pesticides use and progress still remains to be made towards more sustainable practices. Pest Monitoring Networks (PMNs) can provide useful information for improving crop protection by restricting…

Populations and Evolution · Quantitative Biology 2020-02-05 Marie-Josée Cros , Jean-Noël Aubertot , Sabrina Gaba , Xavier Reboud , Régis Sabbadin , Nathalie Peyrard