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We present LLaMA-Adapter, a lightweight adaption method to efficiently fine-tune LLaMA into an instruction-following model. Using 52K self-instruct demonstrations, LLaMA-Adapter only introduces 1.2M learnable parameters upon the frozen…

Computer Vision and Pattern Recognition · Computer Science 2024-09-20 Renrui Zhang , Jiaming Han , Chris Liu , Peng Gao , Aojun Zhou , Xiangfei Hu , Shilin Yan , Pan Lu , Hongsheng Li , Yu Qiao

Fine-tuning-as-a-service introduces a threat to Large Language Models' safety when service providers fine-tune their models on poisoned user-submitted datasets, a process known as harmful fine-tuning attacks. In this work, we show that by…

Machine Learning · Computer Science 2026-03-03 Quoc Minh Nguyen , Trung Le , Jing Wu , Anh Tuan Bui , Mehrtash Harandi

The prediction of amyloidogenicity in peptides and proteins remains a focal point of ongoing bioinformatics. The crucial step in this field is to apply advanced computational methodologies. Many recent approaches to predicting…

Machine Learning · Computer Science 2025-08-19 Zohra Yagoub , Hafida Bouziane

Antibodies, a prominent class of approved biologics, play a crucial role in detecting foreign antigens. The effectiveness of antigen neutralisation and elimination hinges upon the strength, sensitivity, and specificity of the…

Quantitative Methods · Quantitative Biology 2023-09-06 Bruna Moreira da Silva , David B. Ascher , Nicholas Geard , Douglas E. V. Pires

Med42-v2 introduces a suite of clinical large language models (LLMs) designed to address the limitations of generic models in healthcare settings. These models are built on Llama3 architecture and fine-tuned using specialized clinical data.…

Computation and Language · Computer Science 2024-08-13 Clément Christophe , Praveen K Kanithi , Tathagata Raha , Shadab Khan , Marco AF Pimentel

The application of Artificial Intelligence has become a powerful approach to detecting software vulnerabilities. However, effective vulnerability detection relies on accurately capturing the semantic structure of code and its contextual…

Software Engineering · Computer Science 2025-05-12 José Gonçalves , Miguel Silva , Eva Maia , Isabel Praça

Timely and effective vulnerability patching is essential for cybersecurity defense, for which various approaches have been proposed yet still struggle to generate valid and correct patches for real-world vulnerabilities. In this paper, we…

Cryptography and Security · Computer Science 2025-04-04 Yu Nong , Haoran Yang , Long Cheng , Hongxin Hu , Haipeng Cai

Safety fine-tuning of language models typically requires a curated adversarial dataset. We take a different approach: score each candidate prompt's difficulty by how often the target model's own rollouts are judged harmful, then fine-tune…

Machine Learning · Computer Science 2026-05-06 Prakhar Gupta , Garv Shah , Donghua Zhang

Tokenization is a central component of natural language processing in current large language models (LLMs), enabling models to convert raw text into processable units. Although learned tokenizers are widely adopted, they exhibit notable…

This project explores large language models (LLMs) for anomaly detection across heterogeneous log sources. Traditional intrusion detection systems suffer from high false positive rates, semantic blindness, and data scarcity, as logs are…

Cryptography and Security · Computer Science 2026-02-09 Yassine Chagna , Antal Goldschmidt

Retrieval-augmented generation (RAG) on specialized domain datasets has shown improved performance when large language models (LLMs) are fine-tuned for generating responses to user queries. In this study, we develop a cybersecurity…

Machine Learning · Computer Science 2024-11-05 Varun Badrinath Krishna

Human Activity Recognition (HAR) is a core task in pervasive computing systems, where models must operate under strict computational constraints while remaining robust to heterogeneous and evolving deployment conditions. Recent advances…

Machine Learning · Computer Science 2026-05-13 Aleksandr Bredikhin , Philippe Lalanda , German Vega

We study the problem of optimizing Large Language Model (LLM) inference scheduling to minimize total latency. LLM inference is an online and multi-task service process and also heavily energy consuming by which a pre-trained LLM processes…

Machine Learning · Computer Science 2025-09-03 Zixi Chen , Yinyu Ye , Zijie Zhou

The adaptive immune system is a natural diagnostic and therapeutic. It recognizes threats earlier than clinical symptoms manifest and neutralizes antigen with exquisite specificity. Recognition specificity and broad reactivity is enabled…

Quantitative Methods · Quantitative Biology 2019-07-26 Alex J. Brown , Igor Snapkov , Rahmad Akbar , Milena Pavlović , Enkelejda Miho , Geir K. Sandve , Victor Greiff

Low-Rank Adaptation (LoRA) has emerged as an efficient method for fine-tuning large language models (LLMs) and is widely adopted within the open-source community. However, the decentralized dissemination of LoRA adapters through platforms…

Cryptography and Security · Computer Science 2025-12-23 Linzhi Chen , Yang Sun , Hongru Wei , Yuqi Chen

The prediction of protein-ligand binding affinity is of great significance for discovering lead compounds in drug research. Facing this challenging task, most existing prediction methods rely on the topological and/or spatial structure of…

Biomolecules · Quantitative Biology 2022-09-28 Yang Zhang , Gengmo Zhou , Zhewei Wei , Hongteng Xu

AI developers often apply safety alignment procedures to prevent the misuse of their AI systems. For example, before Meta released Llama 2-Chat - a collection of instruction fine-tuned large language models - they invested heavily in safety…

Machine Learning · Computer Science 2024-05-24 Simon Lermen , Charlie Rogers-Smith , Jeffrey Ladish

Chemical synthesis, as a foundational methodology in the creation of transformative molecules, exerts substantial influence across diverse sectors from life sciences to materials and energy. Current chemical synthesis practices emphasize…

Dense retrieval calls for discriminative embeddings to represent the semantic relationship between query and document. It may benefit from the using of large language models (LLMs), given LLMs' strong capability on semantic understanding.…

Computation and Language · Computer Science 2025-11-25 Zheng Liu , Chaofan Li , Shitao Xiao , Yingxia Shao , Defu Lian

The remarkable performance of large language models (LLMs) in generation tasks has enabled practitioners to leverage publicly available models to power custom applications, such as chatbots and virtual assistants. However, the data used to…

Artificial Intelligence · Computer Science 2025-03-28 Yuetai Li , Zhangchen Xu , Fengqing Jiang , Luyao Niu , Dinuka Sahabandu , Bhaskar Ramasubramanian , Radha Poovendran