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Due to the scarcity of annotated data and the substantial computational costs of model, conventional tuning methods in medical image segmentation face critical challenges. Current approaches to adapting pretrained models, including…

Computer Vision and Pattern Recognition · Computer Science 2025-12-05 Chenlin Xu , Lei Zhang , Lituan Wang , Xinyu Pu , Pengfei Ma , Guangwu Qian , Zizhou Wang , Yan Wang

The Segment Anything Model (SAM) has recently gained popularity in the field of image segmentation due to its impressive capabilities in various segmentation tasks and its prompt-based interface. However, recent studies and individual…

Computer Vision and Pattern Recognition · Computer Science 2024-01-01 Junde Wu , Wei Ji , Yuanpei Liu , Huazhu Fu , Min Xu , Yanwu Xu , Yueming Jin

While the Segment Anything Model (SAM) excels in semantic segmentation for general-purpose images, its performance significantly deteriorates when applied to medical images, primarily attributable to insufficient representation of medical…

Computer Vision and Pattern Recognition · Computer Science 2023-11-07 Yiming Zhang , Tianang Leng , Kun Han , Xiaohui Xie

The Segment Anything Model (SAM) has achieved remarkable successes in the realm of natural image segmentation, but its deployment in the medical imaging sphere has encountered challenges. Specifically, the model struggles with medical…

Computer Vision and Pattern Recognition · Computer Science 2024-08-02 Shreyank N Gowda , David A. Clifton

The Segment Anything Model (SAM), a foundation model for general image segmentation, has demonstrated impressive zero-shot performance across numerous natural image segmentation tasks. However, SAM's performance significantly declines when…

Computer Vision and Pattern Recognition · Computer Science 2023-09-19 Cheng Chen , Juzheng Miao , Dufan Wu , Zhiling Yan , Sekeun Kim , Jiang Hu , Aoxiao Zhong , Zhengliang Liu , Lichao Sun , Xiang Li , Tianming Liu , Pheng-Ann Heng , Quanzheng Li

Recent advancements in biomedical image analysis have been significantly driven by the Segment Anything Model (SAM). This transformative technology, originally developed for general-purpose computer vision, has found rapid application in…

Computer Vision and Pattern Recognition · Computer Science 2024-01-17 Ho Hin Lee , Yu Gu , Theodore Zhao , Yanbo Xu , Jianwei Yang , Naoto Usuyama , Cliff Wong , Mu Wei , Bennett A. Landman , Yuankai Huo , Alberto Santamaria-Pang , Hoifung Poon

Recently, developing unified medical image segmentation models gains increasing attention, especially with the advent of the Segment Anything Model (SAM). SAM has shown promising binary segmentation performance in natural domains, however,…

Computer Vision and Pattern Recognition · Computer Science 2024-12-18 Shuangping Huang , Hao Liang , Qingfeng Wang , Chulong Zhong , Zijian Zhou , Miaojing Shi

Segmentation quality assessment (SQA) plays a critical role in the deployment of a medical image based AI system. Users need to be informed/alerted whenever an AI system generates unreliable/incorrect predictions. With the introduction of…

Image and Video Processing · Electrical Eng. & Systems 2023-12-18 Yizhe Zhang , Shuo Wang , Tao Zhou , Qi Dou , Danny Z. Chen

Recent advancements in foundation models, such as the Segment Anything Model (SAM), have shown strong performance in various vision tasks, particularly image segmentation, due to their impressive zero-shot segmentation capabilities.…

Computer Vision and Pattern Recognition · Computer Science 2025-05-12 Pengfei Gu , Haoteng Tang , Islam A. Ebeid , Jose A. Nunez , Fabian Vazquez , Diego Adame , Marcus Zhan , Huimin Li , Bin Fu , Danny Z. Chen

This paper addresses the domain adaptation challenge for semantic segmentation in medical imaging. Despite the impressive performance of recent foundational segmentation models like SAM on natural images, they struggle with medical domain…

Computer Vision and Pattern Recognition · Computer Science 2025-01-14 Javier Gamazo Tejero , Moritz Schmid , Pablo Márquez Neila , Martin S. Zinkernagel , Sebastian Wolf , Raphael Sznitman

Training segmentation models for medical images continues to be challenging due to the limited availability of data annotations. Segment Anything Model (SAM) is a foundation model that is intended to segment user-defined objects of interest…

Computer Vision and Pattern Recognition · Computer Science 2023-08-09 Maciej A. Mazurowski , Haoyu Dong , Hanxue Gu , Jichen Yang , Nicholas Konz , Yixin Zhang

Segmentation is a fundamental problem in surgical scene analysis using artificial intelligence. However, the inherent data scarcity in this domain makes it challenging to adapt traditional segmentation techniques for this task. To tackle…

Computer Vision and Pattern Recognition · Computer Science 2023-08-08 Jay N. Paranjape , Nithin Gopalakrishnan Nair , Shameema Sikder , S. Swaroop Vedula , Vishal M. Patel

The Segment Anything Model (SAM) represents a state-of-the-art research advancement in natural image segmentation, achieving impressive results with input prompts such as points and bounding boxes. However, our evaluation and recent…

Computer Vision and Pattern Recognition · Computer Science 2023-08-31 Junlong Cheng , Jin Ye , Zhongying Deng , Jianpin Chen , Tianbin Li , Haoyu Wang , Yanzhou Su , Ziyan Huang , Jilong Chen , Lei Jiang , Hui Sun , Junjun He , Shaoting Zhang , Min Zhu , Yu Qiao

Background: The segment-anything model (SAM), introduced in April 2023, shows promise as a benchmark model and a universal solution to segment various natural images. It comes without previously-required re-training or fine-tuning specific…

Image and Video Processing · Electrical Eng. & Systems 2023-05-09 Sheng He , Rina Bao , Jingpeng Li , Jeffrey Stout , Atle Bjornerud , P. Ellen Grant , Yangming Ou

Foundation medical segmentation models, with MedSAM being the most popular, have achieved promising performance across organs and lesions. However, MedSAM still suffers from compromised performance on specific lesions with intricate…

Quantitative Methods · Quantitative Biology 2025-07-16 Kecheng Chen , Xinyu Luo , Tiexin Qin , Jie Liu , Hui Liu , Victor Ho Fun Lee , Hong Yan , Haoliang Li

Medical image segmentation is a key task in the imaging workflow, influencing many image-based decisions. Traditional, fully-supervised segmentation models rely on large amounts of labeled training data, typically obtained through manual…

Image and Video Processing · Electrical Eng. & Systems 2025-11-04 Tyler Ward , Meredith K. Owen , O'Kira Coleman , Brian Noehren , Abdullah-Al-Zubaer Imran

Segment Anything Model (SAM) has recently achieved amazing results in the field of natural image segmentation. However, it is not effective for medical image segmentation, owing to the large domain gap between natural and medical images. In…

Image and Video Processing · Electrical Eng. & Systems 2024-04-24 Zhengzheng Tu , Le Gu , Xixi Wang , Bo Jiang

Recently, the Segment Anything Model (SAM) has demonstrated promising segmentation capabilities in a variety of downstream segmentation tasks. However in the context of universal medical image segmentation there exists a notable performance…

Image and Video Processing · Electrical Eng. & Systems 2024-10-08 Chao Qin , Jiale Cao , Huazhu Fu , Fahad Shahbaz Khan , Rao Muhammad Anwer

Test time Adaptation is a promising approach for mitigating domain shift in medical image segmentation; however, current evaluations remain limited in terms of modality coverage, task diversity, and methodological consistency. We present…

Computer Vision and Pattern Recognition · Computer Science 2025-12-03 Wenjing Yu , Shuo Jiang , Yifei Chen , Shuo Chang , Yuanhan Wang , Beining Wu , Jie Dong , Mingxuan Liu , Shenghao Zhu , Feiwei Qin , Changmiao Wang , Qiyuan Tian

In this paper, we address the challenge of image resolution variation for the Segment Anything Model (SAM). SAM, known for its zero-shot generalizability, exhibits a performance degradation when faced with datasets with varying image sizes.…

Computer Vision and Pattern Recognition · Computer Science 2024-03-21 Yiran Song , Qianyu Zhou , Xiangtai Li , Deng-Ping Fan , Xuequan Lu , Lizhuang Ma
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