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Positron emission tomography (PET) is widely used in various clinical applications, including cancer diagnosis, heart disease and neuro disorders. The use of radioactive tracer in PET imaging raises concerns due to the risk of radiation…

Computer Vision and Pattern Recognition · Computer Science 2017-12-13 Junshen Xu , Enhao Gong , John Pauly , Greg Zaharchuk

Deep learning has significantly advanced PET image re-construction, achieving remarkable improvements in image quality through direct training on sinogram or image data. Traditional methods often utilize masks for inpainting tasks, but…

Computer Vision and Pattern Recognition · Computer Science 2025-03-12 Bin Huang , Binzhong He , Yanhan Chen , Zhili Liu , Xinyue Wang , Binxuan Li , Qiegen Liu

In this paper, we review physics- and data-driven reconstruction techniques for simultaneous positron emission tomography (PET) / magnetic resonance imaging (MRI) systems, which have significant advantages for clinical imaging of cancer,…

Image and Video Processing · Electrical Eng. & Systems 2022-06-15 Abhejit Rajagopal , Andrew P. Leynes , Nicholas Dwork , Jessica E. Scholey , Thomas A. Hope , Peder E. Z. Larson

Direct reconstruction of positron emission tomography (PET) data using deep neural networks is a growing field of research. Initial results are promising, but often the networks are complex, memory utilization inefficient, produce…

Image and Video Processing · Electrical Eng. & Systems 2020-06-16 William Whiteley , Vladimir Panin , Chuanyu Zhou , Jorge Cabello , Deepak Bharkhada , Jens Gregor

Positron emission tomography (PET) suffers from severe resolution limitations which limit its quantitative accuracy. In this paper, we present a super-resolution (SR) imaging technique for PET based on convolutional neural networks (CNNs).…

Image and Video Processing · Electrical Eng. & Systems 2021-07-29 Tzu-An Song , Samadrita Roy Chowdhury , Fan Yang , Joyita Dutta

Deep learning has been recently shown to improve performance in the domain of synthetic aperture sonar (SAS) image classification. Given the constant resolution with range of a SAS, it is no surprise that deep learning techniques perform so…

Computer Vision and Pattern Recognition · Computer Science 2020-10-27 Isaac D. Gerg , Vishal Monga

Diffusion models have recently enabled state-of-the-art reconstruction of positron emission tomography (PET) images while requiring only image training data. However, domain shift remains a key concern for clinical adoption: priors trained…

Medical Physics · Physics 2025-10-16 George Webber , Alexander Hammers , Andrew P. King , Andrew J. Reader

We develop and evaluate MlPET, a fast localized machine learning approach for probabilistic PET image analysis addressing the noise-resolution trade-off in conventional reconstructions. MlPET replaces computationally demanding Markov chain…

Medical Physics · Physics 2026-01-27 Thomas Mejer Hansen , Nana Christensen , Mikkel Vendelbo

This paper studies the performance of a recently proposed preconditioned stochastic gradient descent (PSGD) algorithm on recurrent neural network (RNN) training. PSGD adaptively estimates a preconditioner to accelerate gradient descent, and…

Machine Learning · Statistics 2016-12-09 Xi-Lin Li

An image or volume of interest in positron emission tomography (PET) is reconstructed from pairs of gamma rays emitted from a radioactive substance. Many image reconstruction methods are based on estimation of pixels or voxels on some…

Signal Processing · Electrical Eng. & Systems 2019-06-18 Azra Tafro , Damir Seršić , Ana Sović Kržić

Stochastic Gradient Descent (SGD) is a workhorse in machine learning, yet its slow convergence can be a computational bottleneck. Variance reduction techniques such as SAG, SVRG and SAGA have been proposed to overcome this weakness,…

Machine Learning · Computer Science 2016-02-29 Thomas Hofmann , Aurelien Lucchi , Simon Lacoste-Julien , Brian McWilliams

Data-driven approaches recently achieved remarkable success in magnetic resonance imaging (MRI) reconstruction, but integration into clinical routine remains challenging due to a lack of generalizability and interpretability. In this paper,…

Image and Video Processing · Electrical Eng. & Systems 2023-10-20 Martin Zach , Florian Knoll , Thomas Pock

Dose reduction in computed tomography (CT) is essential for decreasing radiation risk in clinical applications. Iterative reconstruction is one of the most promising ways to compensate for the increased noise due to reduction of photon…

Image and Video Processing · Electrical Eng. & Systems 2021-03-24 Zhuonan He , Yikun Zhang , Yu Guan , Shanzhou Niu , Yi Zhang , Yang Chen , Qiegen Liu

In this paper we combine the stochastic variance reduced gradient (SVRG) method [17] with the primal dual fixed point method (PDFP) proposed in [7] to solve a sum of two convex functions and one of which is linearly composite. This type of…

Optimization and Control · Mathematics 2020-07-24 Ya-Nan Zhu , Xiaoqun Zhang

We develop a novel preconditioning method for ridge regression, based on recent linear sketching methods. By equipping Stochastic Variance Reduced Gradient (SVRG) with this preconditioning process, we obtain a significant speed-up relative…

Machine Learning · Computer Science 2016-05-27 Alon Gonen , Francesco Orabona , Shai Shalev-Shwartz

Emerging unsupervised implicit neural representation (INR) methods, such as NeRP, NeAT, and SCOPE, have shown great potential to address sparse-view computed tomography (SVCT) inverse problems. Although these INR-based methods perform well…

Image and Video Processing · Electrical Eng. & Systems 2025-02-11 Xuanyu Tian , Lixuan Chen , Qing Wu , Chenhe Du , Jingjing Shi , Hongjiang Wei , Yuyao Zhang

PET super-resolution is highly under-constrained because paired multi-resolution scans from the same subject are rarely available, and effective resolution is determined by scanner-specific physics (e.g., PSF, detector geometry, and…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Liutao Yang , Zi Wang , Peiyuan Jing , Xiaowen Wang , Javier A. Montoya-Zegarra , Kuangyu Shi , Daoqiang Zhang , Guang Yang

Positron emission tomography (PET) reconstruction is a critical challenge in molecular imaging, often hampered by noise amplification, structural blurring, and detail loss due to sparse sampling and the ill-posed nature of inverse problems.…

Computer Vision and Pattern Recognition · Computer Science 2026-02-13 Mengxiao Geng , Zijie Chen , Ran Hong , Bingxuan Li , Qiegen Liu

Positron Emission Tomography (PET) image reconstruction is inherently challenged by Poisson noise and physical degradation factors, which are further exacerbated in limited-angle acquisitions. While deep learning methods demonstrate…

Computer Vision and Pattern Recognition · Computer Science 2026-05-11 Rüveyda Yilmaz , Yuli Wu , Johannes Stegmaier , Volkmar Schulz

Model-based iterative reconstruction plays a key role in solving inverse problems. However, the associated minimization problems are generally large-scale, nonsmooth, and sometimes even nonconvex, which present challenges in designing…

Image and Video Processing · Electrical Eng. & Systems 2025-10-21 Tao Hong , Zhaoyi Xu , Jason Hu , Jeffrey A. Fessler