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Electron ptychography enables dose-efficient atomic-resolution imaging, but conventional reconstruction algorithms suffer from noise sensitivity, slow convergence, and extensive manual hyperparameter tuning for regularization, especially in…

Image and Video Processing · Electrical Eng. & Systems 2025-11-12 Arthur R. C. McCray , Stephanie M. Ribet , Georgios Varnavides , Colin Ophus

Regularized empirical risk minimization (rERM) has become important in data-intensive fields such as genomics and advertising, with stochastic gradient methods typically used to solve the largest problems. However, ill-conditioned…

Machine Learning · Statistics 2025-01-28 Jingruo Sun , Zachary Frangella , Madeleine Udell

List-mode positron emission tomography (PET) image reconstruction is an important tool for PET scanners with many lines-of-response and additional information such as time-of-flight and depth-of-interaction. Deep learning is one possible…

Medical Physics · Physics 2024-02-13 Kibo Ote , Fumio Hashimoto , Yuya Onishi , Takashi Isobe , Yasuomi Ouchi

Implicit neural representations (INRs) have demonstrated strong capabilities in various medical imaging tasks, such as denoising, registration, and segmentation, by representing images as continuous functions, allowing complex details to be…

Image and Video Processing · Electrical Eng. & Systems 2025-03-31 Younès Moussaoui , Diana Mateus , Nasrin Taheri , Saïd Moussaoui , Thomas Carlier , Simon Stute

Pre-trained models with large-scale training data, such as CLIP and Stable Diffusion, have demonstrated remarkable performance in various high-level computer vision tasks such as image understanding and generation from language…

Computer Vision and Pattern Recognition · Computer Science 2024-03-20 Xiaogang Xu , Shu Kong , Tao Hu , Zhe Liu , Hujun Bao

The well-designed structures in neural networks reflect the prior knowledge incorporated into the models. However, though different models have various priors, we are used to training them with model-agnostic optimizers such as SGD. In this…

Machine Learning · Computer Science 2023-02-10 Xiaohan Ding , Honghao Chen , Xiangyu Zhang , Kaiqi Huang , Jungong Han , Guiguang Ding

Diffusion models (DMs) have recently been introduced as a regularizing prior for PET image reconstruction, integrating DMs trained on high-quality PET images with unsupervised schemes that condition on measured data. While these approaches…

Medical Physics · Physics 2026-03-18 George Webber , Alexander Hammers , Andrew P King , Andrew J Reader

To obtain high-quality positron emission tomography (PET) scans while reducing radiation exposure to the human body, various approaches have been proposed to reconstruct standard-dose PET (SPET) images from low-dose PET (LPET) images. One…

Image and Video Processing · Electrical Eng. & Systems 2023-08-22 Zeyu Han , Yuhan Wang , Luping Zhou , Peng Wang , Binyu Yan , Jiliu Zhou , Yan Wang , Dinggang Shen

PET image reconstruction is challenging due to the ill-poseness of the inverse problem and limited number of detected photons. Recently deep neural networks have been widely and successfully used in computer vision tasks and attracted…

Computer Vision and Pattern Recognition · Computer Science 2017-10-11 Kuang Gong , Jiahui Guan , Kyungsang Kim , Xuezhu Zhang , Georges El Fakhri , Jinyi Qi , Quanzheng Li

Parameter-efficient tunings (PETs) have demonstrated impressive performance and promising perspectives in training large models, while they are still confronted with a common problem: the trade-off between learning new content and…

Machine Learning · Computer Science 2024-07-18 Jingyang Qiao , Zhizhong Zhang , Xin Tan , Yanyun Qu , Wensheng Zhang , Zhi Han , Yuan Xie

Dynamic positron emission tomography (dPET) image reconstruction is extremely challenging due to the limited counts received in individual frame. In this paper, we propose a spatial-temporal convolutional primal dual network (STPDnet) for…

Image and Video Processing · Electrical Eng. & Systems 2023-03-09 Rui Hu , Jianan Cui , Chengjin Yu , Yunmei Chen , Huafeng Liu

Direct reconstruction methods have been developed to estimate parametric images directly from the measured PET sinograms by combining the PET imaging model and tracer kinetics in an integrated framework. Due to limited counts received,…

Image and Video Processing · Electrical Eng. & Systems 2021-06-22 Kuang Gong , Ciprian Catana , Jinyi Qi , Quanzheng Li

Recent work has shown improved lesion detectability and flexibility to reconstruction hyperparameters (e.g. scanner geometry or dose level) when PET images are reconstructed by leveraging pre-trained diffusion models. Such methods train a…

Medical Physics · Physics 2025-08-28 George Webber , Alexander Hammers , Andrew P. King , Andrew J. Reader

To obtain high-quality positron emission tomography (PET) while minimizing radiation exposure, a range of methods have been designed to reconstruct standard-dose PET (SPET) from corresponding low-dose PET (LPET) images. However, most…

Image and Video Processing · Electrical Eng. & Systems 2024-04-11 Yuchen Fei , Yanmei Luo , Yan Wang , Jiaqi Cui , Yuanyuan Xu , Jiliu Zhou , Dinggang Shen

Although sparse-view computed tomography (CT) has significantly reduced radiation dose, it also introduces severe artifacts which degrade the image quality. In recent years, deep learning-based methods for inverse problems have made…

Image and Video Processing · Electrical Eng. & Systems 2024-01-02 Shuo Xu , Yucheng Zhang , Gang Chen , Xincheng Xiang , Peng Cong , Yuewen Sun

Anatomically guided PET reconstruction using MRI information has been shown to have the potential to improve PET image quality. However, these improvements are limited to PET scans with paired MRI information. In this work we employed a…

Image and Video Processing · Electrical Eng. & Systems 2024-03-28 Weijie Gan , Huidong Xie , Carl von Gall , Günther Platsch , Michael T. Jurkiewicz , Andrea Andrade , Udunna C. Anazodo , Ulugbek S. Kamilov , Hongyu An , Jorge Cabello

Positron emission tomography (PET) is widely used for clinical diagnosis. As PET suffers from low resolution and high noise, numerous efforts try to incorporate anatomical priors into PET image reconstruction, especially with the…

Medical Physics · Physics 2019-12-17 Nuobei Xie , Kuang Gong , Ning Guo , Zhixin Qin , Zhifang Wu , Huafeng Liu , Quanzheng Li

Photoacoustic imaging (PAI) suffers from inherent limitations that can degrade the quality of reconstructed results, such as noise, artifacts and incomplete data acquisition caused by sparse sampling or partial array detection. In this…

Optics · Physics 2025-01-07 Yu Zhang , Shuang Li , Yibing Wang , Yu Sun , Wenyi Xiang

Positron emission tomography (PET) is a widely used, highly sensitive molecular imaging in clinical diagnosis. There is interest in reducing the radiation exposure from PET but also maintaining adequate image quality. Recent methods using…

Image and Video Processing · Electrical Eng. & Systems 2024-10-28 Yuxin Xue , Lei Bi , Yige Peng , Michael Fulham , David Dagan Feng , Jinman Kim

This paper develops a method of biologically guided deep learning for post-radiation FDG-PET image outcome prediction based on pre-radiation images and radiotherapy dose information. Based on the classic reaction-diffusion mechanism, a…