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In digital pathology, whole-slide images routinely exceed gigapixel resolution, making computationally intensive generative super-resolution (SR) impractical for routine deployment. We introduce CAFlow, an adaptive-depth single-step…

Computer Vision and Pattern Recognition · Computer Science 2026-03-20 Elad Yoshai , Ariel D. Yoshai , Natan T. Shaked

Reconstructing PDE solutions from sparse observations is a core challenge in scientific computing. We present FM4PDE, a flow-matching generative framework that learns the joint distribution of PDE coefficients (or initial states) and…

Machine Learning · Statistics 2026-05-26 Xifeng Zhang , Jin Zhao

Flow Matching (FM) policies have emerged as an efficient backbone for robotic control, offering fast and expressive action generation that underpins recent large-scale embodied AI systems. However, FM policies trained via imitation learning…

Robotics · Computer Science 2026-04-14 Xiaotian Qiu , Lukai Chen , Jinhao Li , Qi Sun , Cheng Zhuo , Guohao Dai

Diffusion models (DMs) have demonstrated remarkable success in real-world image super-resolution (SR), yet their reliance on time-consuming multi-step sampling largely hinders their practical applications. While recent efforts have…

Computer Vision and Pattern Recognition · Computer Science 2026-05-13 Jiaqi Xu , Wenbo Li , Haoze Sun , Fan Li , Zhixin Wang , Long Peng , Jingjing Ren , Haoran Yang , Xiaowei Hu , Renjing Pei , Pheng-Ann Heng

Rectified flow and reflow procedures have significantly advanced fast generation by progressively straightening ordinary differential equation (ODE) flows. They operate under the assumption that image and noise pairs, known as couplings,…

Machine Learning · Computer Science 2024-11-04 Dogyun Park , Sojin Lee , Sihyeon Kim , Taehoon Lee , Youngjoon Hong , Hyunwoo J. Kim

Reinforcement Fine-Tuning (RFT) on flow-based models is crucial for preference alignment. However, they often introduce visual hallucinations like over-optimized details and semantic misalignment. This work preliminarily explores why visual…

Computer Vision and Pattern Recognition · Computer Science 2026-02-04 Xiaofeng Tan , Jun Liu , Yuanting Fan , Bin-Bin Gao , Xi Jiang , Xiaochen Chen , Jinlong Peng , Chengjie Wang , Hongsong Wang , Feng Zheng

Diffusion- and flow-based models have advanced Real-world Image Super-Resolution (Real-ISR), but their multi-step sampling makes inference slow and hard to deploy. One-step distillation alleviates the cost, yet often degrades restoration…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Ruiqing Wang , Kai Zhang , Yuanzhi Zhu , Hanshu Yan , Shilin Lu , Jian Yang

Inferring the number of distinct components contributing to an observation, while simultaneously estimating their parameters, remains a long-standing challenge across signal processing, astrophysics, and neuroscience. Classical…

Instrumentation and Methods for Astrophysics · Physics 2025-12-01 Niklas Houba , Giovanni Giarda , Lorenzo Speri

While inorganic retrosynthesis planning is essential in the field of chemical science, the application of machine learning in this area has been notably less explored compared to organic retrosynthesis planning. In this paper, we propose…

Machine Learning · Computer Science 2025-10-14 Heewoong Noh , Namkyeong Lee , Gyoung S. Na , Chanyoung Park

Single-cell RNA sequencing (scRNA-seq) provides high-dimensional profiles of cellular states, enabling data-driven modeling of cellular dynamics over time. In practice, time-resolved scRNA-seq is collected at only a few discrete time points…

Machine Learning · Computer Science 2026-05-22 Siyu Pu , Qingqing Long , Xiaohan Huang , Haotian Chen , Jiajia Wang , Meng Xiao , Xiao Luo , Hengshu Zhu , Yuanchun Zhou , Xuezhi Wang

Recent progress has expanded the use of large language models (LLMs) in drug discovery, including synthesis planning. However, objective evaluation of retrosynthesis performance remains limited. Existing benchmarks and metrics typically…

Tilted (entropic) risk, obtained by applying a log-exponential transform to a base loss, is a well established tool in statistics and machine learning for emphasizing rare or high loss events while retaining a tractable optimization…

Machine Learning · Computer Science 2025-12-04 Vahid R. Ramezani , Benjamin Englard

Multi-turn interaction remains challenging for online reinforcement learning. A common solution is trajectory-level optimization, which treats each trajectory as a single training sample. However, this approach can be inefficient and yield…

Artificial Intelligence · Computer Science 2025-11-18 Yuhan Chen , Yuxuan Liu , Long Zhang , Pengzhi Gao , Jian Luan , Wei Liu

Standard masked discrete diffusion models face limitations in reasoning tasks due to their inability to correct their own mistakes on the masking path. Since they rely on a fixed number of denoising steps, they are unable to adjust their…

Machine Learning · Computer Science 2026-03-26 Gregor Kornhardt , Jannis Chemseddine , Christian Wald , Gabriele Steidl

Various template-based and template-free approaches have been proposed for single-step retrosynthesis prediction in recent years. While these approaches demonstrate strong performance from a data-driven metrics standpoint, many model…

Machine Learning · Computer Science 2023-08-15 Kevin Zhang , Vipul Mann , Venkat Venkatasubramanian

Flow matching has recently emerged as a powerful alternative to diffusion models, providing a continuous-time formulation for generative modeling and representation learning. Yet, we show that this framework suffers from a fundamental…

Machine Learning · Computer Science 2025-09-26 Weili Zeng , Yichao Yan

Flow Matching (FM) constructs linear conditional probability paths, but the learned marginal velocity field inevitably exhibits strong curvature due to trajectory superposition. This curvature severely inflates numerical truncation errors,…

Machine Learning · Computer Science 2026-04-07 Tauhid Khan

Optical flow estimation is crucial to a variety of vision tasks. Despite substantial recent advancements, achieving real-time on-device optical flow estimation remains a complex challenge. First, an optical flow model must be sufficiently…

Computer Vision and Pattern Recognition · Computer Science 2024-04-15 Jamie Menjay Lin , Jisoo Jeong , Hong Cai , Risheek Garrepalli , Kai Wang , Fatih Porikli

The wide application of flow-matching methods has greatly promoted the development of robot imitation learning. However, these methods all face the problem of high inference time. To address this issue, researchers have proposed…

Robotics · Computer Science 2025-10-23 Yu Fang , Xinyu Wang , Xuehe Zhang , Wanli Xue , Mingwei Zhang , Shengyong Chen , Jie Zhao

Data-driven methods are emerging as efficient alternatives to traditional numerical forecasting, offering fast inference and lower computational cost. Yet, for complex systems, long-term accuracy often deteriorates due to error…

Machine Learning · Computer Science 2025-09-03 Hao Zhou , Sibo Cheng