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Iterative generative models such as Flow Matching and Diffusion models have demonstrated strong test-time scaling behavior, where additional inference computation can improve generation quality. In contrast, Drift Models offer efficient…

Machine Learning · Computer Science 2026-05-19 Chenrui Ma , Xi Xiao , Lin Zhao , Tianyang Wang , Ferdinando Fioretto , Yanning Shen

In image restoration, single-step discriminative mappings often lack fine details via expectation learning, whereas generative paradigms suffer from inefficient multi-step sampling and noise-residual coupling. To address this dilemma, we…

Computer Vision and Pattern Recognition · Computer Science 2026-04-22 Zihao Fan , Xin Lu , Jie Xiao , Dong Li , Jie Huang , Xueyang Fu

Recent advances in few-step diffusion distillation have enabled efficient image generation, yet aligning these models with human preferences remains challenging. We propose Reward-Tilted Distribution Matching Distillation (RTDMD), a…

Computer Vision and Pattern Recognition · Computer Science 2026-05-29 Yushi Huang , Xiangxin Zhou , Ruoyu Wang , Chi Zhang , Jun Zhang , Tianyu Pang

Discrete flow matching generates text by iteratively transforming noise tokens into coherent language, but may require hundreds of forward passes. Distillation uses the multi-step trajectory to train a student to reproduce the process in a…

Machine Learning · Computer Science 2026-05-11 Amin Karimi Monsefi , Dominic Culver , Nikhil Bhendawade , Manuel R. Ciosici , Yizhe Zhang , Irina Belousova

Retrosynthesis is a problem to infer reactant compounds to synthesize a given product compound through chemical reactions. Recent studies on retrosynthesis focus on proposing more sophisticated prediction models, but the dataset to feed the…

Machine Learning · Computer Science 2020-10-05 Katsuhiko Ishiguro , Kazuya Ujihara , Ryohto Sawada , Hirotaka Akita , Masaaki Kotera

Recent advances in large multi-modal generative models have demonstrated impressive capabilities in multi-modal generation, including image and video generation. These models are typically built upon multi-step frameworks like diffusion and…

Computer Vision and Pattern Recognition · Computer Science 2026-01-29 Zhenglin Cheng , Peng Sun , Jianguo Li , Tao Lin

Retrosynthesis poses a key challenge in biopharmaceuticals, aiding chemists in finding appropriate reactant molecules for given product molecules. With reactants and products represented as 2D graphs, retrosynthesis constitutes a…

Machine Learning · Computer Science 2025-07-22 Yiming Wang , Yuxuan Song , Yiqun Wang , Minkai Xu , Rui Wang , Hao Zhou , Wei-Ying Ma

In silico tools are important for generating novel hypotheses and exploring alternatives in de novo metabolic pathway design. However, while many computational frameworks have been proposed for retrobiosynthesis, few successful examples of…

Machine Learning · Computer Science 2026-04-16 Peter Zhiping Zhang , Jeffrey D. Varner

Learning-based optical flow estimation has been dominated with the pipeline of cost volume with convolutions for flow regression, which is inherently limited to local correlations and thus is hard to address the long-standing challenge of…

Computer Vision and Pattern Recognition · Computer Science 2022-07-19 Haofei Xu , Jing Zhang , Jianfei Cai , Hamid Rezatofighi , Dacheng Tao

Robot manipulation has increasingly adopted data-driven generative policy frameworks, yet the field faces a persistent trade-off: diffusion models suffer from high inference latency, while flow-based methods often require complex…

Robotics · Computer Science 2026-01-30 Han Fang , Yize Huang , Yuheng Zhao , Paul Weng , Xiao Li , Yutong Ban

Discrete diffusion models excel at visual synthesis but rely on slow, iterative decoding. Existing single-step distillation methods attempt to bypass this bottleneck, either by training auxiliary score networks that effectively double…

Computer Vision and Pattern Recognition · Computer Science 2026-05-21 Chaoyang Wang , Yunhai Tong

Traditional discriminative computer vision relies predominantly on static projections, mapping input features to outputs in a single computational step. Although efficient, this paradigm lacks the iterative refinement and robustness…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Om Govind Jha , Manoj Bamniya , Ayon Borthakur

Centralized trajectory optimization in the joint space of multiple robots allows access to a larger feasible space that can result in smoother trajectories, especially while planning in tight spaces. Unfortunately, it is often…

Robotics · Computer Science 2026-04-22 Simon Idoko , Prajyot Jadhav , Arun Kumar Singh

Dataset distillation compresses large datasets into compact synthetic sets with comparable performance in training models. Despite recent progress on diffusion-based distillation, this type of method typically depends on heuristic guidance…

Machine Learning · Computer Science 2026-02-06 Xuhui Li , Zhengquan Luo , Xiwei Liu , Yongqiang Yu , Zhiqiang Xu

Rectified Flow (RF) models have advanced high-quality image and video synthesis via optimal transport theory. However, when applied to image-to-image translation, they still depend on costly multi-step denoising, hindering real-time…

Computer Vision and Pattern Recognition · Computer Science 2025-11-26 Shengqian Li , Ming Gao , Yi Liu , Zuzeng Lin , Feng Wang , Feng Dai

Defect segmentation is central to computer vision based inspection of infrastructure assets during both construction and operation. However, deployment remains limited due to scarce pixel-level labels and domain shift across environments.…

Computer Vision and Pattern Recognition · Computer Science 2026-01-13 Babak Asadi , Peiyang Wu , Mani Golparvar-Fard , Ramez Hajj

Retrosynthetic planning is a fundamental problem in chemistry for finding a pathway of reactions to synthesize a target molecule. Recently, search algorithms have shown promising results for solving this problem by using deep neural…

Machine Learning · Computer Science 2021-06-10 Junsu Kim , Sungsoo Ahn , Hankook Lee , Jinwoo Shin

Retrosynthesis is the process of recursively decomposing target molecules into available building blocks. It plays an important role in solving problems in organic synthesis planning. To automate or assist in the retrosynthesis analysis,…

Quantitative Methods · Quantitative Biology 2020-11-06 Chaochao Yan , Qianggang Ding , Peilin Zhao , Shuangjia Zheng , Jinyu Yang , Yang Yu , Junzhou Huang

Retrosynthesis is the process of determining the set of reactant molecules that can react to form a desired product. Semi-template-based retrosynthesis methods, which imitate the reverse logic of synthesis reactions, first predict the…

Machine Learning · Computer Science 2024-04-01 Frazier N. Baker , Ziqi Chen , Daniel Adu-Ampratwum , Xia Ning

Segmenting thin structures like infrastructure cracks and anatomical vessels is a task hampered by topology-sensitive geometry, high annotation costs, and poor generalization across domains. Existing methods address these challenges in…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Babak Asadi , Peiyang Wu , Mani Golparvar-Fard , Viraj Shah , Ramez Hajj
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