Related papers: A note on metapopulation models
Compartmental models are the most widely used framework for modeling infectious diseases. These models have been continuously refined to incorporate all the realistic mechanisms that can shape the course of an epidemic outbreak. Building on…
The basic reproductive number -- $R_0$ -- is one of the most common and most commonly misapplied numbers in public health. Although often used to compare outbreaks and forecast pandemic risk, this single number belies the complexity that…
The propagations of diseases, behaviors and information in real systems are rarely independent of each other, but they are coevolving with strong interactions. To uncover the dynamical mechanisms, the evolving spatiotemporal patterns and…
Compartmental models are valuable tools for investigating infectious diseases. Researchers building such models typically begin with a simple structure where compartments correspond to individuals with different epidemiological statuses,…
Infectious disease transmission in human populations has a complex two-way interaction with changes in host behaviour. It is increasingly recognised that incorporating adaptive behavioural change into epidemic models is important for…
Accurate estimates of the reproduction ratio are crucial to project infectious disease epidemic evolution and guide public health response. Here, we prove that estimates of the reproduction ratio based on inference from surveillance data…
The COVID-19 crisis has shown that we can only prevent the risk of mass contagion through timely, large-scale, coordinated, and decisive actions. However, frequently the models used by experts [from whom decision-makers get their main…
Discrete and Continuous Dynamics is the first in a series of articles on Network Models for Epidemiology. This project began in the Fall quarter of 2014 in my continuous modeling course. Since then, it has taken off and turned into a series…
We show that the basic reproduction number of an SIS patch model with standard incidence is either strictly decreasing and strictly convex with respect to the diffusion coefficient of infected subpopulation if the patch reproduction numbers…
We discuss the failure of monotonicity properties for even simple compartmental epidemic models, for the case where transmission rates are non-constant. We also identify a special case in which monotonicity holds.
Early estimates of the transmission potential of emerging and re-emerging infections are increasingly used to inform public health authorities on the level of risk posed by outbreaks. Existing methods to estimate the reproduction number…
Many real networks are not isolated from each other but form networks of networks, often interrelated in non trivial ways. Here, we analyze an epidemic spreading process taking place on top of two interconnected complex networks. We develop…
Here, we consider an SIS epidemic model where the individuals are distributed on several distinct patches. We construct a stochastic model and then prove that it converges to a deterministic model as the total population size tends to…
COVID-19 has resulted in a public health global crisis. The pandemic control necessitates epidemic models that capture the trends and impacts on infectious individuals. Many exciting models can implement this but they lack practical…
The theory of life history evolution provides a powerful framework to understand the evolutionary dynamics of pathogens in both epidemic and endemic situations. This framework, however, relies on the assumption that pathogen populations are…
The possible dynamics of an ecosystem with three interconnected patches among which one population can migrate are investigated, paying attention to the consequences that possible disruption in the communicating paths can cause.
We consider multiple diseases spreading in a static Configuration Model network. We make standard assumptions that infection transmits from neighbor to neighbor at a disease-specific rate and infected individuals recover at a…
Deterministic compartmental models have been used extensively in modeling epidemic propagation. These models are required to fit available data and numerical procedures are often implemented to this end. But not every model architecture is…
Human diseases spread over networks of contacts between individuals and a substantial body of recent research has focused on the dynamics of the spreading process. Here we examine a model of two competing diseases spreading over the same…
In this paper, we propose and analyze a reaction-diffusion susceptible-infected-susceptible (SIS) epidemic patch model. The individuals are assumed to reside in different patches, where they are able to move inside and among the patches.…