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Maternal sugar consumption in utero may have a variety of effects on offspring. We exploit the abolishment of the rationing of sweet confectionery in the UK on April 24, 1949, and its subsequent reintroduction some months later, in an era…
We address the challenge of causal inference status and the dose-response effects with a semi-continuous exposure. A two-stage approach is proposed using estimating equation for multiple outcomes with large sample properties derived for the…
Epidemiological evidence supports an association between exposure to air pollution during pregnancy and birth and child health outcomes. Typically, such associations are estimated by regressing an outcome on daily or weekly measures of…
In this article, we investigate group differences in phthalate exposure profiles using NHANES data. Phthalates are a family of industrial chemicals used in plastics and as solvents. There is increasing evidence of adverse health effects of…
This project is based on the dataset "exposome_NA.RData", which contains a subcohort of 1301 mother-child pairs who were enrolled into the HELIX study during pregnancy. Several health outcomes were measured on the child at birth or at age…
Purpose: Factor analysis (FA) has become part and parcel in metabolic syndrome (MBS) research. Both exploration- and confirmation-driven factor analyzes are rampant. However, factor analytic results on MBS differ widely. A situation that is…
Exposures to environmental chemicals during gestation can alter health status later in life. Most studies of maternal exposure to chemicals during pregnancy have focused on a single chemical exposure observed at high temporal resolution.…
Child dehydration is a significant health concern, especially among children under 5 years of age who are more susceptible to diarrhea and vomiting. In Afghanistan, severe diarrhea contributes to child mortality due to dehydration. However,…
Obesity is one of the major health risk factors be- hind the rise of non-communicable conditions. Understanding the factors influencing obesity is very complex since there are many variables that can affect the health behaviors leading to…
Visceral adipose tissue (VAT) is a key marker of both metabolic health and habitual physical activity (PA). Excess VAT is highly correlated with type 2 diabetes and insulin resistance. The mechanistic basis for this pathophysiology relates…
We address measurement error bias in propensity score (PS) analysis due to covariates that are latent variables. In the setting where latent covariate $X$ is measured via multiple error-prone items $\mathbf{W}$, PS analysis using several…
Obesity is a risk factor for many health issues, including heart disease, diabetes, osteoarthritis, and certain cancers. One of the primary behavioral causes, dietary intake, has proven particularly challenging to measure and track. Current…
Clinicians often investigate the body mass index (BMI) trajectories of children to assess their growth with respect to their peers, as well as to anticipate future growth and disease risk. While retrospective modelling of BMI trajectories…
The researchers have drawn much attention about the birth weight of newborn babies in the last three decades. The birth weight is one of the vital roles in the babys health. So many researchers such as (2),(1) and (4) analyzed the birth…
Estimating the joint effect of a multivariate, continuous exposure is crucial, particularly in environmental health where interest lies in simultaneously evaluating the impact of multiple environmental pollutants on health. We develop novel…
Babies born with low and very low birthweights -- i.e., birthweights below 2,500 and 1,500 grams, respectively -- have an increased risk of complications compared to other babies, and the proportion of babies with a low birthweight is a…
We propose the spatial-temporal aggregated predictor (STAP) modeling framework to address measurement and estimation issues that arise when assessing the relationship between built environment features (BEF) and health outcomes. Many BEFs…
Obesity is one of the leading health concerns in the United States. Researchers and health care providers are interested in understanding factors affecting obesity and detecting the likelihood of obesity as early as possible. In this paper,…
Bias in medical AI is often framed as a problem of representation. However, in image-based tasks such as fetal ultrasound, performance disparities can arise even when representation is adequate, because predictive accuracy depends strongly…
Modeling dose-response relationships of drugs is essential to understanding their effect on patient outcomes under realistic circumstances. While intention-to-treat analyses of clinical trials provide the effect of assignment to a…