Related papers: Prenatal phthalate exposures and adiposity outcome…
Low-dose ionizing radiation may induce far-reaching consequences in human, especially regarding intrauterine development. Many studies have documented that the risks of in utero irradiation remain controversial and no effect is reported at…
In this article, we analyze perinatal data with birth weight (BW) as primarily interesting response variable. Gestational age (GA) is usually an important covariate and included in polynomial form. However, in opposition to this univariate…
\noindent\textbf{Background} Prenatal glucocorticoid exposure alters cardiac development, but whether persistent cardiac effects in childhood follow a dose-response relationship remains unknown. We recently showed that ECG foundation models…
Background: Overweight and obesity are an increasing phenomenon worldwide. Predicting future overweight or obesity early in the childhood reliably could enable a successful intervention by experts. While a lot of research has been done…
Objective: We hypothesized that prenatal stress (PS) exerts lasting impact on fetal heart rate (fHR). We sought to validate the presence of such PS signature in fHR by measuring coupling between maternal HR (mHR) and fHR. Study design:…
Often linear regression is used to perform mediation analysis. However, in many instances, the underlying relationships may not be linear, as in the case of placental-fetal hormones and fetal development. Although, the exact functional form…
This paper proposes a Bayesian hierarchical model to characterize the relationship between birth weight and maternal pre-eclampsia across gestation at a large maternity hospital in urban Uganda. Key scientific questions we investigate…
Maternal obesity is associated with increased risk of diabetes, cardiovascular disease and hypertension in adult offspring. Midlife hypercholesterolemia and hypertension are risk factors for Alzheimer's disease, suggesting that the ageing…
Diet plays a crucial role in health, and understanding the causal effects of dietary patterns is essential for informing public health policy and personalized nutrition strategies. However, causal inference in nutritional epidemiology faces…
Unmeasured confounding can severely bias causal effect estimates from spatiotemporal observational data, especially when the confounders do not vary smoothly in time and space. In this work, we develop a method for addressing unmeasured…
Monitoring maternal and fetal health during pregnancy is crucial for preventing adverse outcomes. While tests such as ultrasound scans offer high accuracy, they can be costly and inconvenient. Telehealth and more accessible body shape…
Childhood obesity is a major public health challenge. Early prediction and identification of the children at a high risk of developing childhood obesity may help in engaging earlier and more effective interventions to prevent and manage…
Purpose: To improve on the original form of Fat DESPOT, a multiparametric mapping technique that returns the fat- and water-specific estimates of $R_1$ ($R_{1f}$, $R_{1w}$), $R_2^*$ , and proton density fat fraction (PDFF) by upgrading the…
Background:Adverse reproductive history is a multisystemic risk factor, but evidence is constrained by isolated outcome studies, limited adjustment, and non-interpretable algorithmic models. We re-frame the estimand from prediction to…
Falls are common in people with Parkinson's disease (PD) and have detrimental effects which can lower the quality of life. While studies have been conducted to learn about falling in general, factors distinguishing injurious from…
Rheumatoid arthritis (RA) has an intricate etiology that includes environmental factors as well as genetics. Organophosphate esters (OPEs) are frequently used as chemical additives in many personal care products and household items.…
A century of plastic usage has led to an accumulation of plastic waste in waterways and oceans. Over time, these wastes break down into particles smaller than 5 microns -- or ''microplastics'' -- which can infiltrate human biological…
Epidemiological research supports an association between maternal exposure to air pollution during pregnancy and adverse children's health outcomes. Advances in exposure assessment and statistics allow for estimation of both critical…
Evidence from animal models and epidemiological studies has linked prenatal alcohol exposure (PAE) to a broad range of long-term cognitive and behavioral deficits. However, there is virtually no information in the scientific literature…
Our Bayesian approach to Mendelian Randomisation uses multiple instruments to assess the putative causal effect of an exposure on an outcome. The approach is robust to violations of the (untestable) Exclusion Restriction condition, and…