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Opioid Use Disorder (OUD) has reached an epidemic level in the US. Diversion of unused prescription opioids to secondary users and black market significantly contributes to the abuse and misuse of these highly addictive drugs, leading to…

Optimization and Control · Mathematics 2022-10-17 Md Mahmudul Hasan , Tasnim Ibn Faiz , Alicia Sasser Modestino , Gary J. Young , Md. Noor-E-Alam

Data collected from arrays of sensors are essential for informed decision-making in various systems. However, the presence of anomalies can compromise the accuracy and reliability of insights drawn from the collected data or information…

Applications · Statistics 2024-03-19 Katie Buchhorn , Kerrie Mengersen , Edgar Santos-Fernandez , James McGree

Opioid related deaths are increasing dramatically in recent years, and opioid epidemic is worsening in the United States. Combating opioid epidemic becomes a high priority for both the U.S. government and local governments such as New York…

Populations and Evolution · Quantitative Biology 2019-01-14 Xin Chen , Yu Wang , Xiaxia Yu , Elinor Schoenfeld , Mary Saltz , Joel Saltz , Fusheng Wang

Opioid use disorder (OUD) continuously poses major public health challenges and social implications worldwide with dramatic rise of opioid dependence leading to potential abuse. Despite that a few pharmacological agents have been approved…

Biomolecules · Quantitative Biology 2023-01-13 Hongsong Feng , Rana Elladki , Jian Jiang , Guo-Wei Wei

Small area estimation (SAE) entails estimating characteristics of interest for domains, often geographical areas, in which there may be few or no samples available. SAE has a long history and a wide variety of methods have been suggested,…

Applications · Statistics 2020-06-19 Jon Wakefield , Taylor Okonek , Jon Pedersen

Out-of-Domain (OOD) detection is a key component in a task-oriented dialog system, which aims to identify whether a query falls outside the predefined supported intent set. Previous softmax-based detection algorithms are proved to be…

Computation and Language · Computer Science 2022-09-15 Yanan Wu , Zhiyuan Zeng , Keqing He , Yutao Mou , Pei Wang , Weiran Xu

When analyzing spatially referenced event data, the criteria for declaring rates as "reliable" is still a matter of dispute. What these varying criteria have in common, however, is that they are rarely satisfied for crude estimates in small…

Methodology · Statistics 2023-02-10 Harrison Quick , Guangzi Song

Despite of the great efforts during the censuses, occurrence of some nonsampling errors such as coverage error is inevitable. Coverage error which can be classified into two types of under-count and overcount occurs when there is no unique…

Applications · Statistics 2019-10-15 Sepideh Mosaferi

Improving health worldwide will require rigorous quantification of population-level trends in health status. However, global-level surveys are not available, forcing researchers to rely on fragmentary country-specific data of varying…

Methodology · Statistics 2014-05-20 Mariel M. Finucane , Christopher J. Paciorek , Goodarz Danaei , Majid Ezzati

Categorical response data are ubiquitous in complex survey applications, yet few methods model the dependence across different outcome categories when the response is ordinal. Likewise, few methods exist for the common combination of a…

Methodology · Statistics 2025-02-24 Daniel Vedensky , Paul A. Parker , Scott H. Holan

We focus on the problem of uncertainty informed allocation of medical resources (vaccines) to heterogeneous populations for managing epidemic spread. We tackle two related questions: (1) For a compartmental ordinary differential equation…

Optimization and Control · Mathematics 2023-07-04 Samarth Gupta , Saurabh Amin

Typical Bayesian approaches to OOD detection use epistemic uncertainty. Surprisingly from the Bayesian perspective, there are a number of methods that successfully use aleatoric uncertainty to detect OOD points (e.g. Hendryks et al. 2018).…

Machine Learning · Statistics 2021-10-29 Xi Wang , Laurence Aitchison

Despite their successes, deep neural networks may make unreliable predictions when faced with test data drawn from a distribution different to that of the training data, constituting a major problem for AI safety. While this has recently…

Machine Learning · Computer Science 2020-07-16 Erik Daxberger , José Miguel Hernández-Lobato

The discovery of disease subtypes is an essential step for developing precision medicine, and disease subtyping via omics data has become a popular approach. While promising, subtypes obtained from conventional approaches may not be…

Applications · Statistics 2023-09-28 Lingsong Meng , Zhiguang Huo

This study introduces the Spatial Health and Population Estimator (SHAPE), a spatial microsimulation framework that applies hierarchical iterative proportional fitting (IPF) to estimate two health risk behaviors and eleven health outcomes…

Applications · Statistics 2025-10-28 Emma Von Hoene , Aanya Gupta , Hamdi Kavak , Amira Roess , Taylor Anderson

Opioid related aberrant behaviors (ORABs) present novel risk factors for opioid overdose. This paper introduces a novel biomedical natural language processing benchmark dataset named ODD, for ORAB Detection Dataset. ODD is an…

Computation and Language · Computer Science 2024-03-26 Sunjae Kwon , Xun Wang , Weisong Liu , Emily Druhl , Minhee L. Sung , Joel I. Reisman , Wenjun Li , Robert D. Kerns , William Becker , Hong Yu

Bayesian networks are powerful statistical models to study the probabilistic relationships among set random variables with major applications in disease modeling and prediction. Here, we propose a continuous time Bayesian network with…

Machine Learning · Computer Science 2021-07-16 Syed Hasib Akhter Faruqui , Adel Alaeddini , Jing Wang , Carlos A. Jaramillo

Accurate estimation of the change in crime over time is a critical first step towards better understanding of public safety in large urban environments. Bayesian hierarchical modeling is a natural way to study spatial variation in urban…

Applications · Statistics 2022-06-22 Cecilia Balocchi , Sameer K. Deshpande , Edward I. George , Shane T. Jensen

Regional aggregates of health outcomes over delineated administrative units (e.g., states, counties, zip codes), or areal units, are widely used by epidemiologists to map mortality or incidence rates and capture geographic variation. To…

Methodology · Statistics 2022-05-03 Leiwen Gao , Sudipto Banerjee , Beate Ritz

Introduction: Substance use disorders (SUDs) have emerged as a pressing public health concern in the United States, with adolescent substance use often leading to SUDs in adulthood. Effective strategies are needed to stem this progression.…

Applications · Statistics 2025-05-29 Tingfang Wang , Joseph M. Boden , Swati Biswas , Pankaj K. Choudhary
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