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We consider the problem of asynchronous online testing, aimed at providing control of the false discovery rate (FDR) during a continual stream of data collection and testing, where each test may be a sequential test that can start and stop…

Methodology · Statistics 2020-08-25 Tijana Zrnic , Aaditya Ramdas , Michael I. Jordan

We develop a new class of distribution--free multiple testing rules for false discovery rate (FDR) control under general dependence. A key element in our proposal is a symmetrized data aggregation (SDA) approach to incorporating the…

Methodology · Statistics 2021-05-27 Lilun Du , Xu Guo , Wenguang Sun , Changliang Zou

AI-Scientist systems that use large language models to automate research risk generating spurious discoveries through uncontrolled multiple testing. We present a functional architecture that enforces statistical rigor at two levels: a…

Software Engineering · Computer Science 2026-02-09 Karen Sargsyan

In large-scale multiple hypothesis testing problems, the false discovery exceedance (FDX) provides a desirable alternative to the widely used false discovery rate (FDR) when the false discovery proportion (FDP) is highly variable. We…

Methodology · Statistics 2023-04-21 Pallavi Basu , Luella Fu , Alessio Saretto , Wenguang Sun

In contemporary research, online error control is often required, where an error criterion, such as familywise error rate (FWER) or false discovery rate (FDR), shall remain under control while testing an a priori unbounded sequence of…

Methodology · Statistics 2024-09-13 Lasse Fischer , Marta Bofill Roig , Werner Brannath

Algorithms that ensure reproducible findings from large-scale, high-dimensional data are pivotal in numerous signal processing applications. In recent years, multivariate false discovery rate (FDR) controlling methods have emerged,…

Methodology · Statistics 2024-01-31 Jasin Machkour , Michael Muma , Daniel P. Palomar

As datasets grow richer, an important challenge is to leverage the full features in the data to maximize the number of useful discoveries while controlling for false positives. We address this problem in the context of multiple hypotheses…

Methodology · Statistics 2017-11-21 Fei Xia , Martin J. Zhang , James Zou , David Tse

This paper presents a powerful methodology for flexible full-data nonparametric novelty detection that offers distribution-free false discovery rate (FDR) control guarantees. Building on the full conformal inference framework and the…

Methodology · Statistics 2026-04-21 Junu Lee , Ilia Popov , Zhimei Ren

The e-BH procedure is an e-value-based multiple testing procedure that provably controls the false discovery rate (FDR) under any dependence structure between the e-values. Despite this appealing theoretical FDR control guarantee, the e-BH…

Methodology · Statistics 2024-04-29 Junu Lee , Zhimei Ren

As a form of artificial intelligence (AI) technology based on interactive learning, deep reinforcement learning (DRL) has been widely applied across various fields and has achieved remarkable accomplishments. However, DRL faces certain…

Machine Learning · Computer Science 2025-02-18 Geng Sun , Wenwen Xie , Dusit Niyato , Fang Mei , Jiawen Kang , Hongyang Du , Shiwen Mao

A new online multiple testing procedure is described in the context of anomaly detection, which controls the False Discovery Rate (FDR). An accurate anomaly detector must control the false positive rate at a prescribed level while keeping…

Methodology · Statistics 2024-12-17 Etienne Krönert , Alain Célisse , Dalila Hattab

In bandit multiple hypothesis testing, each arm corresponds to a different null hypothesis that we wish to test, and the goal is to design adaptive algorithms that correctly identify large set of interesting arms (true discoveries), while…

Machine Learning · Statistics 2021-11-18 Ziyu Xu , Ruodu Wang , Aaditya Ramdas

Edge Federation is a new computing paradigm that seamlessly interconnects the resources of multiple edge service providers. A key challenge in such systems is the deployment of latency-critical and AI based resource-intensive applications…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-08-17 Shreshth Tuli , Giuliano Casale , Nicholas R. Jennings

Online testing procedures aim to control the extent of false discoveries over a sequence of hypothesis tests, allowing for the possibility that early-stage test results influence the choice of hypotheses to be tested in later stages.…

Methodology · Statistics 2021-10-18 Aaron Fisher

False discovery rate (FDR) has been widely used as an error measure in large scale multiple testing problems, but most research in the area has been focused on procedures for controlling the FDR based on independent test statistics or the…

Methodology · Statistics 2009-09-29 Weihua Tang , Cun-Hui Zhang

Organizations investing in artificial intelligence face a fundamental challenge: traditional return on investment calculations fail to capture the dual nature of AI implementations, which simultaneously reduce certain operational risks…

Computers and Society · Computer Science 2025-12-01 Hernan Huwyler

In hypothesis testing, a false discovery occurs when a hypothesis is incorrectly rejected due to noise in the sample. When adaptively testing multiple hypotheses, the probability of a false discovery increases as more tests are performed.…

Machine Learning · Statistics 2020-10-22 Wanrong Zhang , Gautam Kamath , Rachel Cummings

Motivated by the genomic application of expression quantitative trait loci (eQTL) mapping, we propose a new procedure to perform simultaneous testing of multiple hypotheses using Bayes factors as input test statistics. One of the most…

Methodology · Statistics 2016-06-09 Xiaoquan Wen

Functional dependencies (FDs) are fundamental integrity constraints in relational databases, but discovering them under incremental updates remains challenging. While static algorithms are inefficient due to full re-execution, incremental…

Databases · Computer Science 2026-01-23 Yajuan Xu , Xixian Han , Xiaolong Wan

This paper studies the estimation of high dimensional Gaussian graphical model (GGM). Typically, the existing methods depend on regularization techniques. As a result, it is necessary to choose the regularized parameter. However, the…

Methodology · Statistics 2013-06-06 Weidong Liu