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Conformal inference provides a general distribution-free method to rigorously calibrate the output of any machine learning algorithm for novelty detection. While this approach has many strengths, it has the limitation of being randomized,…

Machine Learning · Computer Science 2023-10-25 Meshi Bashari , Amir Epstein , Yaniv Romano , Matteo Sesia

Consider the online testing of a stream of hypotheses where a real--time decision must be made before the next data point arrives. The error rate is required to be controlled at {all} decision points. Conventional \emph{simultaneous testing…

Methodology · Statistics 2020-03-03 Bowen Gang , Wenguang Sun , Weinan Wang

We propose an alternative framework to existing setups for controlling false alarms when multiple A/B tests are run over time. This setup arises in many practical applications, e.g. when pharmaceutical companies test new treatment options…

Machine Learning · Statistics 2017-11-21 Fanny Yang , Aaditya Ramdas , Kevin Jamieson , Martin J. Wainwright

The recent e-Benjamini-Hochberg (e-BH) procedure for multiple hypothesis testing is known to control the false discovery rate (FDR) under arbitrary dependence between the input e-values. This paper points out an important subtlety when…

Methodology · Statistics 2025-08-06 Hongjian Wang , Sanjit Dandapanthula , Aaditya Ramdas

This paper explores the intrinsic connections between the Bayesian false discovery rate (FDR) control procedures and their counterpart of frequentist procedures. We attempt to offer a unified view of FDR control within and beyond the…

Methodology · Statistics 2018-03-15 Xiaoquan Wen

Biological research often involves testing a growing number of null hypotheses as new data is accumulated over time. We study the problem of online control of the familywise error rate (FWER), that is testing an apriori unbounded sequence…

Methodology · Statistics 2020-03-10 Jinjin Tian , Aaditya Ramdas

One important partition of algorithms for controlling the false discovery rate (FDR) in multiple testing is into offline and online algorithms. The first generally achieve significantly higher power of discovery, while the latter allow…

Methodology · Statistics 2021-03-05 Tijana Zrnic , Daniel L. Jiang , Aaditya Ramdas , Michael I. Jordan

Modern data analysis frequently involves large-scale hypothesis testing, which naturally gives rise to the problem of maintaining control of a suitable type I error rate, such as the false discovery rate (FDR). In many biomedical and…

Methodology · Statistics 2023-07-25 David S. Robertson , James M. S. Wason , Aaditya Ramdas

The increasing prevalence and utility of large, public databases necessitates the development of appropriate methods for controlling false discovery. Motivated by this challenge, we discuss the generic problem of testing a possibly infinite…

Methodology · Statistics 2013-07-03 Ehud Aharoni , Saharon Rosset

In online multiple testing, the hypotheses arrive one by one, and at each time we must immediately reject or accept the current hypothesis solely based on the data and hypotheses observed so far. Many online procedures have been proposed,…

Methodology · Statistics 2026-02-27 Lasse Fischer , Ziyu Xu , Aaditya Ramdas

In this article, we propose a generalized weighted version of the well-known Benjamini-Hochberg (BH) procedure. The rigorous weighting scheme used by our method enables it to encode structural information from simultaneous multi-way…

Methodology · Statistics 2021-05-25 Shinjini Nandi , Sanat K. Sarkar

Motivation: While the analysis of a single RNA sequencing (RNAseq) dataset has been well described in the literature, modern research workflows often have additional complexity in that related RNAseq experiments are performed sequentially…

Quantitative Methods · Quantitative Biology 2022-06-07 Lathan Liou , Milena Hornburg , David S. Robertson

This paper continues the line of research initiated in Liu et. al. (2016) on developing a novel framework for multiple testing of hypotheses grouped in a one-way classified form using hypothesis-specific local false discovery rates…

Methodology · Statistics 2022-11-22 Sanat K. Sarkar , Zhigen Zhao

Modern advances in sensor, computing, and communication technologies enable various smart grid applications. The heavy dependence on communication technology has highlighted the vulnerability of the electricity grid to false data injection…

Cryptography and Security · Computer Science 2018-09-18 Xiangyu Niu Jiangnan Li , Jinyuan Sun

The increasing scale and complexity of mobile applications make automated GUI exploration essential for software quality assurance. However, existing methods often neglect state dependencies between test fragments, which leads to redundant…

Software Engineering · Computer Science 2026-04-03 Jiahui Song , Jiaxin Zhi , Kangjia Zhao , Chen Zhi , Junxiao Han , Xinkui Zhao , Nan Wang , Shuiguang Deng , Jianwei Yin

This paper develops a general framework for controlling the false discovery rate (FDR) in multiple testing of Gaussian means against two-sided alternatives. The widely used Benjamini-Hochberg (BH) procedure provides exact FDR control under…

Methodology · Statistics 2025-11-26 Deepra Ghosh , Sanat K. Sarkar

We introduce a new class of methods for finite-sample false discovery rate (FDR) control in multiple testing problems with dependent test statistics where the dependence is fully or partially known. Our approach separately calibrates a…

Methodology · Statistics 2020-07-22 William Fithian , Lihua Lei

After the seminal Benjamini-Hochberg (BH) procedure for controlling the false discovery rate (FDR) was proposed, dozens of papers have attempted to improve its power by adapting to the unknown proportion of nulls. We observe that most null…

Methodology · Statistics 2026-03-24 Nikolaos Ignatiadis , Ruodu Wang , Aaditya Ramdas

Financial AI systems must produce answers grounded in specific regulatory filings, yet current LLMs fabricate metrics, invent citations, and miscalculate derived quantities. These errors carry direct regulatory consequences as the EU AI…

Artificial Intelligence · Computer Science 2026-04-28 Dongxin Guo , Jikun Wu , Siu Ming Yiu

Automated Uncrewed Aerial Vehicle (UAV) landing is crucial for autonomous UAV services such as monitoring, surveying, and package delivery. It involves detecting landing targets, perceiving obstacles, planning collision-free paths, and…