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We investigate the problem of machine learning-based (ML) predictive inference on individual treatment effects (ITEs). Previous work has focused primarily on developing ML-based meta-learners that can provide point estimates of the…

Machine Learning · Computer Science 2023-08-30 Ahmed Alaa , Zaid Ahmad , Mark van der Laan

Causal Graph Discovery (CGD) is the process of estimating the underlying probabilistic graphical model that represents joint distribution of features of a dataset. CGD-algorithms are broadly classified into two categories: (i)…

Cryptography and Security · Computer Science 2024-10-01 Payel Bhattacharjee , Ravi Tandon

Most of the widely used estimators of the average treatment effect (ATE) in causal inference rely on the assumptions of unconfoundedness and overlap. Unconfoundedness requires that the observed covariates account for all correlations…

Statistics Theory · Mathematics 2025-07-01 Yang Cai , Alkis Kalavasis , Katerina Mamali , Anay Mehrotra , Manolis Zampetakis

The ''Propose-Test-Release'' (PTR) framework is a classic recipe for designing differentially private (DP) algorithms that are data-adaptive, i.e. those that add less noise when the input dataset is nice. We extend PTR to a more general…

Machine Learning · Computer Science 2023-01-03 Rachel Redberg , Yuqing Zhu , Yu-Xiang Wang

Randomized controlled trials (RCTs) have become powerful tools for assessing the impact of interventions and policies in many contexts. They are considered the gold standard for causal inference in the biomedical fields and many social…

Iterative algorithms for differential privacy run for a fixed number of iterations, where each iteration learns some information from data and produces an intermediate output. However, the algorithm only releases the output of the last…

Data Structures and Algorithms · Computer Science 2016-09-13 Jaewoo Lee , Daniel Kifer

Differential Privacy (DP) provides a rigorous framework for releasing statistics while protecting individual information present in a dataset. Although substantial progress has been made on differentially private linear regression, existing…

Statistics Theory · Mathematics 2026-01-16 Getoar Sopa , Marco Avella Medina , Cynthia Rush

How can agents exchange information to learn while protecting privacy? Healthcare centers collaborating on clinical trials must balance knowledge sharing with safeguarding sensitive patient data. We address this challenge by using…

Machine Learning · Computer Science 2025-03-19 Marios Papachristou , M. Amin Rahimian

In order to both learn and protect sensitive training data, there has been a growing interest in privacy preserving machine learning methods. Differential privacy has emerged as an important measure of privacy. We are interested in the…

Cryptography and Security · Computer Science 2025-02-11 Antoine Barczewski , Amal Mawass , Jan Ramon

Differential privacy has become the preeminent technique to protect the privacy of individuals in a database while allowing useful results from data analysis to be shared. Notably, it guarantees the amount of privacy loss in the worst-case…

Cryptography and Security · Computer Science 2024-06-21 Arin Ghazarian , Jianwei Zheng , Cyril Rakovski

We seek to understand the probability an individual benefits from treatment (PIBT), an inestimable quantity that must be bounded in practice. Given the innate uncertainty in the population-level bounds on PIBT, we seek to better understand…

Methodology · Statistics 2024-04-04 Gabriel Ruiz , Oscar Hernan Madrid Padilla

In this paper, we develop a multiply robust inference procedure of the average treatment effect (ATE) for data with high-dimensional covariates. We consider the case where it is difficult to correctly specify a single parametric model for…

Methodology · Statistics 2025-09-03 Xintao Xia , Yumou Qiu

Background: Randomized controlled trials are often used to inform policy and practice for broad populations. The average treatment effect (ATE) for a target population, however, may be different from the ATE observed in a trial if there are…

Differential privacy is a strong notion for privacy that can be used to prove formal guarantees, in terms of a privacy budget, $\epsilon$, about how much information is leaked by a mechanism. However, implementations of privacy-preserving…

Machine Learning · Computer Science 2019-08-14 Bargav Jayaraman , David Evans

Differentially private training algorithms provide protection against one of the most popular attacks in machine learning: the membership inference attack. However, these privacy algorithms incur a loss of the model's classification…

Cryptography and Security · Computer Science 2021-10-13 Jiaxiang Liu , Simon Oya , Florian Kerschbaum

Accurately estimating personalized treatment effects within a study site (e.g., a hospital) has been challenging due to limited sample size. Furthermore, privacy considerations and lack of resources prevent a site from leveraging…

Machine Learning · Statistics 2022-06-17 Xiaoqing Tan , Chung-Chou H. Chang , Ling Zhou , Lu Tang

There is intense interest in applying machine learning to problems of causal inference in fields such as healthcare, economics and education. In particular, individual-level causal inference has important applications such as precision…

Machine Learning · Statistics 2017-05-17 Uri Shalit , Fredrik D. Johansson , David Sontag

Estimation of individualized treatment effects (ITE), also known as conditional average treatment effects (CATE), is an active area of methodology development. However, much less attention has been paid to the quantification of uncertainty…

Methodology · Statistics 2025-04-08 Daijiro Kabata , Nicholas C. Henderson , Ravi Varadhan

Differential privacy (DP) enables safe data release, with synthetic data generation emerging as a common approach in recent years. Yet standard synthesizers preserve all dependencies in the data, including spurious correlations between…

Databases · Computer Science 2026-03-26 Naeim Ghahramanpour , Mostafa Milani

Treatment effect heterogeneity plays an important role in many areas of causal inference and within recent years, estimation of the conditional average treatment effect (CATE) has received much attention in the statistical community. While…

Methodology · Statistics 2024-12-17 Simon Christoffer Ziersen , Torben Martinussen