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Myocardial infarction causes myocardium thinning, fibrosis, and progressive heart failure. Engineered human myocardium (EHM) is tested clinically as a first-in-class product for sustainable remuscularization in patients with advanced heart…

Medical Physics · Physics 2025-08-28 Hossein Goodarzi Hosseinabadi

Numerical simulations to evaluate thoracic aortic hemodynamics include a computational fluid dynamic (CFD) approach or fluid-structure interaction (FSI) approach. While CFD neglects the arterial deformation along the cardiac cycle by…

The human heart is enclosed in the pericardial cavity. The pericardium consists of a layered thin sac and is separated from the myocardium by a thin film of fluid. It provides a fixture in space and frictionless sliding of the myocardium.…

Computational Engineering, Finance, and Science · Computer Science 2018-12-11 Martin R. Pfaller , Julia M. Hörmann , Martina Weigl , Andreas Nagler , Radomir Chabiniok , Cristóbal Bertoglio , Wolfgang A. Wall

Incorrectly sized balloon catheters can lead to increased post-surgical complications, yet even with preoperative imaging, correct selection remains a challenge. With limited feedback during surgery, it is difficult to verify correct…

A stabilized finite element method is introduced for the simulation of time-periodic creeping flows, such as those found in the cardiorespiratory systems. The new technique, which is formulated in the frequency rather than time domain,…

Numerical Analysis · Mathematics 2022-11-30 Mahdi Esmaily

Rapid and accurate simulation of cerebral aneurysm flow modifications by flow diverters (FDs) can help improving patient-specific intervention and predicting treatment outcome. However, with explicit FD devices being placed in…

This review focuses on the computerized modeling of the electrophysiology of the human atria, emphasizing the simulation of common arrhythmias such as atrial flutter (AFlut) and atrial fibrillation (AFib). Which components of the model are…

Computational Physics · Physics 2025-05-30 Olaf Dössel , Axel Loewe

Coronary heart disease (CHD) remains a leading cause of mortality worldwide. This study introduces a novel approach that integrates patient-specific Multi-slice CT scans into CAD models, using a one-dimensional numerical framework to assess…

Medical Physics · Physics 2025-05-21 Priyanshu Ghosh , Sayan Karmakar , Disha Mondal , Oeshee Roy , Supratim Saha

The combination of Finite Element Method (FEM) simulation and experimental photo-elasticity provides both qualitative and quantitative information about the stress field in a polymer composite and particularly along the fibre-matrix…

Materials Science · Physics 2007-05-23 H. Matthias Deuschle , Falk K. Wittel , Henry Gerhard , Gerhard Busse , Bernd-H. Kroeplin

Image-based modeling is essential for understanding cardiovascular hemodynamics and advancing the diagnosis and treatment of cardiovascular diseases. Constructing patient-specific vascular models remains labor-intensive, error-prone, and…

Computer Vision and Pattern Recognition · Computer Science 2025-03-18 Pan Du , Delin An , Chaoli Wang , Jian-Xun Wang

Numerous are the questionings raised by medicine interventionnelle, concerning the hold in charge of the pathologies of the arterial partition (aneurysm, dissection, coarctation, atherosclerosis).for it we made the modeling and the numeric…

Fluid Dynamics · Physics 2009-06-29 H . Alla , M. S. Gueblaoui , M. H. Bensaid

Purpose: Anthropomorphic phantoms can be used in radiotherapy to confirm dose distributions. In this work, a prototype phantom with a deformable chest wall was created based on real human. Methods: A technique similar to 3-dimensional…

Medical Physics · Physics 2021-11-11 Maria Akiki , Fadi Rouphael , Mazen Moussallem

The clinical application of patient-specific modelling of the heart can provide valuable insights in supplementing and advancing methods of diagnosis as well as helping to devise the best possible therapeutic approach for each individual…

Medical Physics · Physics 2023-08-03 Sebastian Skatulla , Carlo Sansour , Mary Familusi , Jagir Hussan , Ntobeko Ntusi

Cardiovascular disease affects millions of people worldwide and its social and economic cost clearly motivates scientific research. Computer simulation can lead to a better understanding of cardiac physiology, and for pathology presents…

Biological Physics · Physics 2023-02-27 Toby Simpson

Knee orthotic devices are widely proposed by physicians and medical practitioners for preventive or therapeutic objectives in relation with their effects, usually known as to stabilize joint or restrict ranges of motion. This study focuses…

Medical Physics · Physics 2014-09-22 Baptiste Pierrat , Jérôme Molimard , Paul Calmels , Laurent Navarro , Stéphane Avril

Progressive aneurysmal dilatation is a well-recognized complication in patients with chronic type B aortic dissection (cTBAD), which may lead to a delayed rupture and create a life-threatening condition. However, our understanding of such…

This paper proposes a computer-assisted system for the surgical treatment of exophthalmia. This treatment is classically characterized by a de-compression of the orbit, by the mean of an orbital walls osteotomy. The plan-ning of this…

Medical Physics · Physics 2007-05-23 Vincent Luboz , Annaig Pedrono , Franck Boutault , Pascal Swider , Yohan Payan

Objectives: The main objective of this review article is to evaluate the usability of Computational Fluid Dynamics (CFD) as a supporting clinical tool for respiratory system. Data Source: The English articles referred for this review paper…

Fluid Dynamics · Physics 2023-10-24 Rajneesh Kashyap , R. Thundil Karuppa Raj

In clinical procedures of angioplasty (i.e., open clogged coronary arteries), devices such as balloons and stents need to be placed and expanded in arteries under the guidance of X-ray fluoroscopy. Due to the limitation of X-ray dose, the…

Computer Vision and Pattern Recognition · Computer Science 2022-07-25 Luojie Huang , Yikang Liu , Li Chen , Eric Z. Chen , Xiao Chen , Shanhui Sun

This paper presents a versatile robotic system for sewing 3D structured object. Leveraging on using a customized robotic sewing device and closed-loop visual servoing control, an all-in-one solution for sewing personalized stent graft is…

Robotics · Computer Science 2018-03-26 Yang Hu , Lin Zhang , Wei Li , Guang-Zhong Yang