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Anomaly detection is an emerging approach in digital pathology for its ability to efficiently and effectively utilize data for disease diagnosis. While supervised learning approaches deliver high accuracy, they rely on extensively annotated…

Image and Video Processing · Electrical Eng. & Systems 2025-08-22 Jiamu Wang , Keunho Byeon , Jinsol Song , Anh Nguyen , Sangjeong Ahn , Sung Hak Lee , Jin Tae Kwak

Pseudo-healthy image inpainting is an essential preprocessing step for analyzing pathological brain MRI scans. Most current inpainting methods favor slice-wise 2D models for their high in-plane fidelity, but their independence across slices…

Image and Video Processing · Electrical Eng. & Systems 2025-07-25 Dou Hoon Kwark , Shirui Luo , Xiyue Zhu , Yudu Li , Zhi-Pei Liang , Volodymyr Kindratenko

Deep learning is widely applied in computer-aided pathological diagnosis, which alleviates the pathologist workload and provide timely clinical analysis. However, most models generally require large-scale annotated data for training, which…

Computer Vision and Pattern Recognition · Computer Science 2024-03-12 Zeyu Liu , Tianyi Zhang , Yufang He , Yunlu Feng , Yu Zhao , Guanglei Zhang

Unsupervised anomaly detection (AD) in medical images aims to identify abnormal regions without relying on pixel-level annotations, which is crucial for scalable and label-efficient diagnostic systems. In this paper, we propose a novel…

Image and Video Processing · Electrical Eng. & Systems 2026-02-05 Jiayu Huo , Jingyuan Hong , Liyun Chen

Unsupervised Out-of-Distribution (OOD) detection consists in identifying anomalous regions in images leveraging only models trained on images of healthy anatomy. An established approach is to tokenize images and model the distribution of…

Computer Vision and Pattern Recognition · Computer Science 2023-08-04 Sergio Naval Marimont , Vasilis Siomos , Giacomo Tarroni

The electrocardiogram (ECG) is an essential tool for diagnosing heart disease, with computer-aided systems improving diagnostic accuracy and reducing healthcare costs. Despite advancements, existing systems often miss rare cardiac anomalies…

Computer Vision and Pattern Recognition · Computer Science 2024-04-09 Aofan Jiang , Chaoqin Huang , Qing Cao , Yuchen Xu , Zi Zeng , Kang Chen , Ya Zhang , Yanfeng Wang

Diffusion models have been recently used for anomaly detection (AD) in images. In this paper we investigate whether they can also be leveraged for AD on multivariate time series (MTS). We test two diffusion-based models and compare them to…

Machine Learning · Computer Science 2023-11-03 Ioana Pintilie , Andrei Manolache , Florin Brad

Medical image synthesis has become an essential strategy for augmenting datasets and improving model generalization in data-scarce clinical settings. However, fine-grained and controllable synthesis remains difficult due to limited…

Image and Video Processing · Electrical Eng. & Systems 2025-09-09 Shuhan Ding , Jingjing Fu , Yu Gu , Naiteek Sangani , Mu Wei , Paul Vozila , Nan Liu , Jiang Bian , Hoifung Poon

In medical imaging, the diffusion models have shown great potential for synthetic image generation tasks. However, these approaches often lack the interpretable connections between the generated and real images and can create anatomically…

Image and Video Processing · Electrical Eng. & Systems 2026-02-12 Jian-Qing Zheng , Yuanhan Mo , Yang Sun , Jiahua Li , Fuping Wu , Ziyang Wang , Tonia Vincent , Bartłomiej W. Papież

Continuous electrocardiogram (ECG) monitoring via wearable devices is vital for early cardiovascular disease detection. However, deploying deep learning models on resource-constrained microcontrollers faces reliability challenges,…

Machine Learning · Computer Science 2026-01-26 Mustafa Fuad Rifet Ibrahim , Maurice Meijer , Alexander Schlaefer , Peer Stelldinger

Traditional deep learning models often lack annotated data, especially in cross-domain applications such as anomaly detection, which is critical for early disease diagnosis in medicine and defect detection in industry. To address this…

Computer Vision and Pattern Recognition · Computer Science 2026-02-06 Wahyu Rahmaniar , Kenji Suzuki

Synthesizing longitudinal medical images at controllable disease stages while preserving patient-specific anatomy is hindered by the entanglement of pathological textures and structural features. We address this challenge for ulcerative…

Computer Vision and Pattern Recognition · Computer Science 2026-05-05 Umut Dundar , Alptekin Temizel

Human mesh recovery (HMR) provides rich human body information for various real-world applications. While image-based HMR methods have achieved impressive results, they often struggle to recover humans in dynamic scenarios, leading to…

Computer Vision and Pattern Recognition · Computer Science 2025-08-20 Ce Zheng , Xianpeng Liu , Qucheng Peng , Tianfu Wu , Pu Wang , Chen Chen

Microaneurysms (MAs), the earliest pathognomonic signs of Diabetic Retinopathy (DR), present as sub-60 $\mu m$ lesions in fundus images with highly variable photometric and morphological characteristics, rendering manual screening not only…

Computer Vision and Pattern Recognition · Computer Science 2025-12-16 Yifei Sun , Yuzhi He , Junhao Jia , Jinhong Wang , Ruiquan Ge , Changmiao Wang , Hongxia Xu

Collective insights from a group of experts have always proven to outperform an individual's best diagnostic for clinical tasks. For the task of medical image segmentation, existing research on AI-based alternatives focuses more on…

Computer Vision and Pattern Recognition · Computer Science 2023-04-11 Aimon Rahman , Jeya Maria Jose Valanarasu , Ilker Hacihaliloglu , Vishal M Patel

Supervised machine learning has enabled accurate pathology detection in brain MRI, but requires training data from diseased subjects that may not be readily available in some scenarios, for example, in the case of rare diseases.…

Image and Video Processing · Electrical Eng. & Systems 2025-06-13 Ana Lawry Aguila , Peirong Liu , Oula Puonti , Juan Eugenio Iglesias

Radiography imaging protocols focus on particular body regions, therefore producing images of great similarity and yielding recurrent anatomical structures across patients. Exploiting this structured information could potentially ease the…

Image and Video Processing · Electrical Eng. & Systems 2024-03-14 Tiange Xiang , Yixiao Zhang , Yongyi Lu , Alan Yuille , Chaoyi Zhang , Weidong Cai , Zongwei Zhou

Segmentation masks of pathological areas are useful in many medical applications, such as brain tumour and stroke management. Moreover, healthy counterfactuals of diseased images can be used to enhance radiologists' training files and to…

Image and Video Processing · Electrical Eng. & Systems 2024-10-02 Alessandro Fontanella , Grant Mair , Joanna Wardlaw , Emanuele Trucco , Amos Storkey

Computer-aided diagnosis for low-dose computed tomography (CT) based on deep learning has recently attracted attention as a first-line automatic testing tool because of its high accuracy and low radiation exposure. However, existing methods…

Image and Video Processing · Electrical Eng. & Systems 2022-06-28 Kyung-Su Kim , Seong Je Oh , Ju Hwan Lee , Myung Jin Chung

Equivocal 3D lesion segmentation exhibits high inter-observer variability. Conventional deterministic models ignore this aleatoric uncertainty, producing over-confident masks that obscure clinical risks. Conversely, while generative methods…

Computer Vision and Pattern Recognition · Computer Science 2026-03-05 Chao Wu , Kangxian Xie , Mingchen Gao