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Anomaly detection (AD) aims at detecting abnormal samples that deviate from the expected normal patterns. Generally, it can be trained merely on normal data, without a requirement for abnormal samples, and thereby plays an important role in…

Computer Vision and Pattern Recognition · Computer Science 2025-02-20 Yu Cai , Weiwen Zhang , Hao Chen , Kwang-Ting Cheng

Unsupervised anomaly detection (UAD) based on deep generative modelling has been increasingly explored for identifying pathological brain abnormalities without requiring voxel-level annotations. By learning the distribution of healthy…

Computer Vision and Pattern Recognition · Computer Science 2026-03-10 Youwan Mahé , Elise Bannier , Stéphanie Leplaideur , Elisa Fromont , Francesca Galassi

This paper investigates the performance of diffusion models for video anomaly detection (VAD) within the most challenging but also the most operational scenario in which the data annotations are not used. As being sparse, diverse,…

Computer Vision and Pattern Recognition · Computer Science 2023-07-04 Anil Osman Tur , Nicola Dall'Asen , Cigdem Beyan , Elisa Ricci

Recent advances in diffusion models have spurred research into their application for Reconstruction-based unsupervised anomaly detection. However, these methods may struggle with maintaining structural integrity and recovering the…

Computer Vision and Pattern Recognition · Computer Science 2025-03-27 Farzad Beizaee , Gregory A. Lodygensky , Christian Desrosiers , Jose Dolz

Neuron segmentation in electron microscopy (EM) aims to reconstruct the complete neuronal connectome; however, current deep learning-based methods are limited by their reliance on large-scale training data and extensive, time-consuming…

Computer Vision and Pattern Recognition · Computer Science 2026-01-23 Liuyun Jiang , Yanchao Zhang , Jinyue Guo , Yizhuo Lu , Ruining Zhou , Hua Han

Diffusion models have advanced unsupervised anomaly detection by improving the transformation of pathological images into pseudo-healthy equivalents. Nonetheless, standard approaches may compromise critical information during pathology…

Image and Video Processing · Electrical Eng. & Systems 2024-03-14 Cosmin I. Bercea , Benedikt Wiestler , Daniel Rueckert , Julia A. Schnabel

Diffusion probabilistic models (DPMs) have exhibited significant effectiveness in computer vision tasks, particularly in image generation. However, their notable performance heavily relies on labelled datasets, which limits their…

Computer Vision and Pattern Recognition · Computer Science 2024-05-09 Keqiang Fan , Xiaohao Cai , Mahesan Niranjan

Medical anomaly detection (AD) is crucial in pathological identification and localization. Current methods typically rely on uncertainty estimation in deep ensembles to detect anomalies, assuming that ensemble learners should agree on…

Computer Vision and Pattern Recognition · Computer Science 2024-09-27 Yi Gu , Yi Lin , Kwang-Ting Cheng , Hao Chen

Inspired by recent findings that generative diffusion models learn semantically meaningful representations, we use them to discover the intrinsic hierarchical structure in biomedical 3D images using unsupervised segmentation. We show that…

Computer Vision and Pattern Recognition · Computer Science 2023-10-11 Nurislam Tursynbek , Marc Niethammer

Medical anomaly detection is a crucial yet challenging task aimed at recognizing abnormal images to assist in diagnosis. Due to the high-cost annotations of abnormal images, most methods utilize only known normal images during training and…

Computer Vision and Pattern Recognition · Computer Science 2023-03-21 Yu Cai , Hao Chen , Xin Yang , Yu Zhou , Kwang-Ting Cheng

Electronic health records (EHRs) are invaluable for clinical research, yet privacy concerns severely restrict data sharing. Synthetic data generation offers a promising solution, but EHRs present unique challenges: they contain both…

Machine Learning · Computer Science 2026-03-26 Shaonan Liu , Yuichiro Iwashita , Soichiro Nakako , Masakazu Iwamura , Koichi Kise

Diffusion models have enabled remarkably high-quality medical image generation, yet it is challenging to enforce anatomical constraints in generated images. To this end, we propose a diffusion model-based method that supports…

Image and Video Processing · Electrical Eng. & Systems 2024-06-21 Nicholas Konz , Yuwen Chen , Haoyu Dong , Maciej A. Mazurowski

Capsule endoscopy has enabled minimally invasive gastrointestinal imaging, but its clinical utility is limited by the inherently low resolution of captured images due to hardware, power, and transmission constraints. This limitation hampers…

Image and Video Processing · Electrical Eng. & Systems 2025-12-30 Haozhe Jia

Graph Anomaly Detection (GAD) is crucial for identifying abnormal entities within networks, garnering significant attention across various fields. Traditional unsupervised methods, which decode encoded latent representations of unlabeled…

Machine Learning · Computer Science 2025-02-26 Jinghan Li , Yuan Gao , Jinda Lu , Junfeng Fang , Congcong Wen , Hui Lin , Xiang Wang

Medical image segmentation models struggle with rare abnormalities due to scarce annotated pathological data. We propose DiffAug a novel framework that combines textguided diffusion-based generation with automatic segmentation validation to…

Computer Vision and Pattern Recognition · Computer Science 2025-08-26 Maham Nazir , Muhammad Aqeel , Francesco Setti

Out-of-Distribution(OOD) detection, a fundamental machine learning task aimed at identifying abnormal samples, traditionally requires model retraining for different inlier distributions. While recent research demonstrates the applicability…

Machine Learning · Computer Science 2025-02-25 Hongzhe Cheng , Tianyou Zheng , Tianyi Zhang , Matthew Johnson-Roberson , Weiming Zhi

Integrating multi-modal clinical data, such as electronic health records (EHR) and chest X-ray images (CXR), is particularly beneficial for clinical prediction tasks. However, in a temporal setting, multi-modal data are often inherently…

Computer Vision and Pattern Recognition · Computer Science 2024-10-24 Wenfang Yao , Chen Liu , Kejing Yin , William K. Cheung , Jing Qin

Recent progress in generative models has made it easier for a wide audience to edit and create image content, raising concerns about the proliferation of deepfakes, especially in healthcare. Despite the availability of numerous techniques…

Image and Video Processing · Electrical Eng. & Systems 2024-10-22 Fred Grabovski , Lior Yasur , Guy Amit , Yisroel Mirsky

Multi-modal magnetic resonance imaging (MRI) provides rich, complementary information for analyzing diseases. However, the practical challenges of acquiring multiple MRI modalities, such as cost, scan time, and safety considerations, often…

Image and Video Processing · Electrical Eng. & Systems 2024-09-16 Zhaohu Xing , Sicheng Yang , Sixiang Chen , Tian Ye , Yijun Yang , Jing Qin , Lei Zhu

Anomaly detection (AD) is the identification of data samples that do not fit a learned data distribution. As such, AD systems can help physicians to determine the presence, severity, and extension of a pathology. Deep generative models,…

Image and Video Processing · Electrical Eng. & Systems 2021-04-12 Jaime Simarro , Ezequiel de la Rosa , Thijs Vande Vyvere , David Robben , Diana M. Sima