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Despite recent success in applying large language models (LLMs) to electronic health records (EHR), most systems focus primarily on assessment rather than treatment planning. We identify three critical limitations in current approaches:…

In this paper, we propose a novel system that integrates state-of-the-art, domain-specific large language models with advanced information retrieval techniques to deliver comprehensive and context-aware responses. Our approach facilitates…

The `pre-train, prompt, predict' paradigm of large language models (LLMs) has achieved remarkable success in open-domain question answering (OD-QA). However, few works explore this paradigm in the scenario of multi-document question…

Computation and Language · Computer Science 2023-12-27 Yu Wang , Nedim Lipka , Ryan A. Rossi , Alexa Siu , Ruiyi Zhang , Tyler Derr

The patient-centered medical dialogue systems strive to offer diagnostic interpretation services to users who are less knowledgeable about medical knowledge, through emphasizing the importance of providing responses specific to the…

Computation and Language · Computer Science 2023-10-19 Chengfeng Dou , Zhi Jin , Wenping Jiao , Haiyan Zhao , Zhenwei Tao , Yongqiang Zhao

Recent years have witnessed the rapid accumulation of massive electronic medical records (EMRs), which highly support the intelligent medical services such as drug recommendation. However, prior arts mainly follow the traditional…

Information Retrieval · Computer Science 2021-02-09 Zhi Zheng , Chao Wang , Tong Xu , Dazhong Shen , Penggang Qin , Baoxing Huai , Tongzhu Liu , Enhong Chen

As the appearance of medical images is influenced by multiple underlying factors, generative models require rich attribute information beyond labels to produce realistic and diverse images. For instance, generating an image of skin lesion…

Computer Vision and Pattern Recognition · Computer Science 2025-07-01 Peng Huang , Junhu Fu , Bowen Guo , Zeju Li , Yuanyuan Wang , Yi Guo

The introduction of large language models (LLMs) has greatly enhanced the capabilities of software agents. Instead of relying on rule-based interactions, agents can now interact in flexible ways akin to humans. However, this flexibility…

Human-Computer Interaction · Computer Science 2026-02-04 Joar Sabel , Mattias Wingren , Andreas Lundell , Sören Andersson , Sara Rosenberg , Susanne Hägglund , Linda Estman , Malin Andtfolk

Visual latent reasoning lets a multimodal large language model (MLLM) create intermediate visual evidence as continuous tokens, avoiding external tools or image generators. However, existing methods usually follow an output-as-input latent…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Yanting Miao , Yutao Sun , Dexin Wang , Mengyu Zhou , Pascal Poupart , Lei Lv , Qi Zhao , Li Wang , Hao Li , Xiaoxi Jiang , Guanjun Jiang

Accurate diagnosis of Alzheimer's disease (AD) requires handling tabular biomarker data, yet such data are often small and incomplete, where deep learning models frequently fail to outperform classical methods. Pretrained large language…

Computation and Language · Computer Science 2026-03-19 Sophie Kearney , Shu Yang , Zixuan Wen , Weimin Lyu , Bojian Hou , Duy Duong-Tran , Tianlong Chen , Jason H. Moore , Marylyn D. Ritchie , Chao Chen , Li Shen

Large language models (LLMs) are increasingly adopted for a variety of tasks with implicit graphical structures, such as planning in robotics, multi-hop question answering or knowledge probing, structured commonsense reasoning, and more.…

Computation and Language · Computer Science 2024-01-09 Heng Wang , Shangbin Feng , Tianxing He , Zhaoxuan Tan , Xiaochuang Han , Yulia Tsvetkov

This study applies Large Language Models (LLMs) to two foundational Electronic Health Record (EHR) data science tasks: structured data querying (using programmatic languages, Python/Pandas) and information extraction from unstructured…

Computation and Language · Computer Science 2026-01-29 Juan Jose Rubio Jan , Jack Wu , Julia Ive

Quantitative Systems Pharmacology (QSP) modeling is essential for drug development but it requires significant time investment that limits the throughput of domain experts. We present \textbf{GRASP} -- a multi-agent, graph-reasoning…

Machine Learning · Computer Science 2025-12-08 Omid Bazgir , Vineeth Manthapuri , Ilia Rattsev , Mohammad Jafarnejad

Large Language Models (LLMs) have shown promising performance on diverse medical benchmarks, highlighting their potential in supporting real-world clinical tasks. Retrieval-Augmented Generation (RAG) has emerged as a key approach for…

Computation and Language · Computer Science 2025-09-30 Kaishuai Xu , Wenjun Hou , Yi Cheng , Wenjie Li

Large language models (LLMs) are widely used, but they often generate subtle factual errors, especially in long-form text. These errors are fatal in some specialized domains such as medicine. Existing fact-checking with grounding documents…

Computation and Language · Computer Science 2025-05-29 Yingjian Chen , Haoran Liu , Yinhong Liu , Jinxiang Xie , Rui Yang , Han Yuan , Yanran Fu , Peng Yuan Zhou , Qingyu Chen , James Caverlee , Irene Li

Continuing advances in Large Language Models (LLMs) in artificial intelligence offer important capacities in intuitively accessing and using medical knowledge in many contexts, including education and training as well as assessment and…

Computation and Language · Computer Science 2024-08-01 Roma Shusterman , Allison C. Waters , Shannon O`Neill , Phan Luu , Don M. Tucker

A ChatGPT-like system for drug compounds could be a game-changer in pharmaceutical research, accelerating drug discovery, enhancing our understanding of structure-activity relationships, guiding lead optimization, aiding drug repurposing,…

Biomolecules · Quantitative Biology 2023-09-11 Youwei Liang , Ruiyi Zhang , Li Zhang , Pengtao Xie

Digital Adoption Platforms (DAPs) have become essential tools for helping employees navigate complex enterprise software such as CRM, ERP, or HRMS systems. Companies like LemonLearning have shown how digital guidance can reduce training…

Software Engineering · Computer Science 2026-05-18 Mohammed Hilel , Yannis Karmim , Jean De Bodinat , Reda Sarehane , Antoine Gillon

Large language models (LLMs) have recently taken the world by storm. They can generate coherent text, hold meaningful conversations, and be taught concepts and basic sets of instructions - such as the steps of an algorithm. In this context,…

Human-Computer Interaction · Computer Science 2023-03-17 Sara Di Bartolomeo , Giorgio Severi , Victor Schetinger , Cody Dunne

With the increasing prevalence of cross-domain Text-Attributed Graph (TAG) Data (e.g., citation networks, recommendation systems, social networks, and ai4science), the integration of Graph Neural Networks (GNNs) and Large Language Models…

Machine Learning · Computer Science 2024-12-18 Xunkai Li , Zhengyu Wu , Jiayi Wu , Hanwen Cui , Jishuo Jia , Rong-Hua Li , Guoren Wang

Large language models (LLMs) have demonstrated remarkable capabilities in a wide range of tasks, yet their application to specialized domains remains challenging due to the need for deep expertise. Retrieval-Augmented generation (RAG) has…

Computation and Language · Computer Science 2025-09-30 Qinggang Zhang , Shengyuan Chen , Yuanchen Bei , Zheng Yuan , Huachi Zhou , Zijin Hong , Hao Chen , Yilin Xiao , Chuang Zhou , Junnan Dong , Yi Chang , Xiao Huang
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