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Large-scale language models (LLMs), such as ChatGPT, are becoming increasingly sophisticated and exhibit human-like capabilities, playing an essential role in assisting humans in a variety of everyday tasks. An important application of AI…

Graph Machine Learning (GML) is receiving growing interest within the pharmaceutical and biotechnology industries for its ability to model biomolecular structures, the functional relationships between them, and integrate multi-omic datasets…

Large language models (LLMs) are transforming the landscape of medicine, yet two fundamental challenges persist: keeping up with rapidly evolving medical knowledge and providing verifiable, evidence-grounded reasoning. Retrieval-augmented…

Drug recommendation (DR) systems aim to support healthcare professionals in selecting appropriate medications based on patients' medical conditions. State-of-the-art approaches utilize deep learning techniques for improving DR, but fall…

Data augmentation is necessary for graph representation learning due to the scarcity and noise present in graph data. Most of the existing augmentation methods overlook the context information inherited from the dataset as they rely solely…

We developed a task-oriented dialogue framework structured as a Directed Acyclic Graph (DAG) of medical questions. The system integrates: (1) a systematic pipeline for transforming medical algorithms and guidelines into a clinical question…

Graph plays an important role in representing complex relationships in real-world applications such as social networks, biological data and citation networks. In recent years, Large Language Models (LLMs) have achieved tremendous success in…

Clinical decision-making is inherently complex, often influenced by cognitive biases, incomplete information, and case ambiguity. Large Language Models (LLMs) have shown promise as tools for supporting clinical decision-making, yet their…

Due to strong capabilities in conducting fluent, multi-turn conversations with users, Large Language Models (LLMs) have the potential to further improve the performance of Conversational Recommender System (CRS). Unlike the aimless…

The advent of Large Language Models (LLMs) has revolutionized natural language processing. However, these models face challenges in retrieving precise information from vast datasets. Retrieval-Augmented Generation (RAG) was developed to…

In our study, we evaluated large language model (LLM) performance on pharmacy licensure-style question-answering tasks and developed an external knowledge integration method to improve accuracy. We benchmarked ten LLMs with varying…

Large language models (LLMs) often struggle with knowledge-intensive tasks due to a lack of background knowledge and a tendency to hallucinate. To address these limitations, integrating knowledge graphs (KGs) with LLMs has been intensively…

Ensuring that Software Requirements Specifications (SRS) align with higher-level organizational or national requirements is vital, particularly in regulated environments such as finance and aerospace. In these domains, maintaining…

Large Language Models (LLMs) often struggle with tasks requiring external knowledge, such as knowledge-intensive Multiple Choice Question Answering (MCQA). Integrating Knowledge Graphs (KGs) can enhance reasoning; however, existing methods…

The integration of multimodal Electronic Health Records (EHR) data has significantly improved clinical predictive capabilities. Leveraging clinical notes and multivariate time-series EHR, existing models often lack the medical context…

In recent years, Large Language Models (LLMs) have demonstrated remarkable proficiency in comprehending and generating natural language, with a growing prevalence in the domain of recommendation systems. However, LLMs still face a…

Large language models (LLMs) have achieved great success in many fields, and recent works have studied exploring LLMs for graph discriminative tasks such as node classification. However, the abilities of LLMs for graph generation remain…

Drug repurposing plays a critical role in accelerating treatment discovery, especially for complex and rare diseases. Biomedical knowledge graphs (KGs), which encode rich clinical associations, have been widely adopted to support this task.…

Effective patient-provider communication is crucial in clinical care, directly impacting patient outcomes and quality of life. Traditional evaluation methods, such as human ratings, patient feedback, and provider self-assessments, are often…

Accurate and safe medication recommendations are critical for effective clinical decision-making, especially in multimorbidity cases. However, existing systems rely on point-wise prediction paradigms that overlook synergistic drug effects…