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Graphs play an important role in representing complex relationships in various domains like social networks, knowledge graphs, and molecular discovery. With the advent of deep learning, Graph Neural Networks (GNNs) have emerged as a…
Participant recruitment based on unstructured medical texts such as clinical notes and radiology reports has been a challenging yet important task for the cohort establishment in clinical research. Recently, Large Language Models (LLMs)…
Generative AI, particularly Large Language Models, increasingly integrates graph-based representations to enhance reasoning, retrieval, and structured decision-making. Despite rapid advances, there remains limited clarity regarding when,…
Large language models (LLM) hold significant potential for applications in biomedicine, but they struggle with hallucinations and outdated knowledge. While retrieval-augmented generation (RAG) is generally employed to address these issues,…
In the era of personalized education, the provision of comprehensible explanations for learning recommendations is of a great value to enhance the learner's understanding and engagement with the recommended learning content. Large language…
One of the most difficult aspects of modeling complex dilemmas in decision-analytic terms is composing a diagram of relevance relations from a set of domain concepts. Decision models in domains such as medicine, however, exhibit certain…
The problem of data sparsity has long been a challenge in recommendation systems, and previous studies have attempted to address this issue by incorporating side information. However, this approach often introduces side effects such as…
Large language models (LLMs) show promise for diagnostic reasoning but often lack reliable, knowledge grounded inference. Knowledge graphs (KGs), such as the Unified Medical Language System (UMLS), offer structured biomedical knowledge that…
Last year has witnessed the considerable interest of Large Language Models (LLMs) for their potential applications in recommender systems, which may mitigate the persistent issue of data sparsity. Though large efforts have been made for…
With the development of Large Language Models (LLM), numerous prompts have been proposed, each with a rich set of features and their own merits. This paper summarizes the prompt words for large language models (LLMs), categorizing them into…
Clinical tasks such as diagnosis and treatment require strong decision-making abilities, highlighting the importance of rigorous evaluation benchmarks to assess the reliability of large language models (LLMs). In this work, we introduce a…
Understanding mechanistic relationships among genes and their impacts on biological pathways is essential for elucidating disease mechanisms and advancing precision medicine. Despite the availability of extensive molecular interaction and…
The transition of Large Language Models (LLMs) from passive knowledge retrievers to autonomous clinical agents demands a shift in evaluation-from static accuracy to dynamic behavioral reliability. To explore this boundary in dentistry, a…
Evidence-based medicine (EBM) plays a crucial role in the application of large language models (LLMs) in healthcare, as it provides reliable support for medical decision-making processes. Although it benefits from current…
Mental health disorders impose a substantial global socioeconomic burden. While large language models (LLMs) offer 24/7, non-judgmental interactions to address this gap, pretrained models lack contextual coherence and emotional alignment…
With the rise of large language models (LLMs), there has been growing interest in Graph Foundation Models (GFMs) for graph-based tasks. By leveraging LLMs as predictors, GFMs have demonstrated impressive generalizability across various…
Recent advancements in large language models (LLMs) have demonstrated extraordinary comprehension capabilities with remarkable breakthroughs on various vision-language tasks. However, the application of LLMs in generating reliable medical…
Recent progress in deep learning is revolutionizing the healthcare domain including providing solutions to medication recommendations, especially recommending medication combination for patients with complex health conditions. Existing…
Drug repurposing is often framed as a candidate identification task, but existing approaches provide limited guidance for distinguishing biologically plausible candidates from historically well-connected ones. Here we introduce DrugKLM, a…
Enhancing interrogation capabilities in Traditional Chinese Medicine (TCM) diagnosis through multi-turn dialogues and knowledge graphs presents a significant challenge for modern AI systems. Current large language models (LLMs), despite…