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We propose a novel method for establishing correspondence between two sequences of 2D images. One particular application of this technique is slice-level content navigation, where the goal is to localize specific 2D slices within a 3D…

Computer Vision and Pattern Recognition · Computer Science 2026-02-16 Dingjie Su , Weixiang Hong , Benoit M. Dawant , Bennett A. Landman

We present an approach to denoising spatial transcriptomics images that is particularly effective for uncovering cell identities in the regime of ultra-low sequencing depths, and also allows for interpolation of gene expression. The method…

Cellular nuclei recognition serves as a fundamental and essential step in the workflow of digital pathology. However, with disparate source organs and staining procedures among histology image clusters, the scanned tiles inherently conform…

Quantitative Methods · Quantitative Biology 2024-07-22 Jianan Fan , Dongnan Liu , Canran Li , Hang Chang , Heng Huang , Filip Braet , Mei Chen , Weidong Cai

Objects with complex structures pose significant challenges to existing instance segmentation methods that rely on boundary or affinity maps, which are vulnerable to small errors around contacting pixels that cause noticeable connectivity…

Computer Vision and Pattern Recognition · Computer Science 2023-10-10 Zudi Lin , Donglai Wei , Aarush Gupta , Xingyu Liu , Deqing Sun , Hanspeter Pfister

Small liver lesions common to colorectal liver metastases (CRLMs) are challenging for convolutional neural network (CNN) segmentation models, especially when we have a wide range of slice thicknesses in the computed tomography (CT) scans.…

Image and Video Processing · Electrical Eng. & Systems 2023-08-31 Mohammad Hamghalam , Richard K. G. Do , Amber L. Simpson

Medical vision-language pre-training methods mainly leverage the correspondence between paired medical images and radiological reports. Although multi-view spatial images and temporal sequences of image-report pairs are available in…

Artificial Intelligence · Computer Science 2024-05-31 Jinxia Yang , Bing Su , Wayne Xin Zhao , Ji-Rong Wen

We propose a marginal super-resolution (MSR) approach based on 2D convolutional neural networks (CNNs) for interpolating an anisotropic brain magnetic resonance scan along the highly under-sampled direction, which is assumed to axial…

Image and Video Processing · Electrical Eng. & Systems 2019-08-16 Cheng Peng , Wei-An Lin , Haofu Liao , Rama Chellappa , S. Kevin Zhou

Deep learning has become the de facto method for medical image segmentation, with 3D segmentation models excelling in capturing complex 3D structures and 2D models offering high computational efficiency. However, segmenting 2.5D images,…

Image and Video Processing · Electrical Eng. & Systems 2024-05-02 Amarjeet Kumar , Hongxu Jiang , Muhammad Imran , Cyndi Valdes , Gabriela Leon , Dahyun Kang , Parvathi Nataraj , Yuyin Zhou , Michael D. Weiss , Wei Shao

With the rapid advancement of Spatial Resolved Transcriptomics (SRT) technology, it is now possible to comprehensively measure gene transcription while preserving the spatial context of tissues. Spatial domain identification and gene…

Genomics · Quantitative Biology 2024-08-14 Donghai Fang , Fangfang Zhu , Dongting Xie , Wenwen Min

Deep learning in k-space has demonstrated great potential for image reconstruction from undersampled k-space data in fast magnetic resonance imaging (MRI). However, existing deep learning-based image reconstruction methods typically apply…

Image and Video Processing · Electrical Eng. & Systems 2020-06-11 Tianming Du , Honggang Zhang , Yuemeng Li , Hee Kwon Song , Yong Fan

Multivariate time series classification is of great importance in practical applications and is a challenging task. However, deep neural network models such as Transformers exhibit high accuracy in multivariate time series classification…

Machine Learning · Computer Science 2024-11-19 Mingsen Du , Yanxuan Wei , Yingxia Tang , Xiangwei Zheng , Shoushui Wei , Cun Ji

Deploying multi-sequence magnetic resonance imaging (MRI) segmentation models to new clinical environments is challenging due to variations in scanners and acquisition protocols. Although existing TTA methods handle basic per-modality…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Zhipeng Deng , Jiale Zhou , Wenhan Jiang , Haolin Wang , Xun Lin , Yafei Ou , Yefeng Zheng

3D Swin Transformer (3D-ST) known for its hierarchical attention and window-based processing, excels in capturing intricate spatial relationships within images. Spatial-spectral Transformer (SST), meanwhile, specializes in modeling…

Computer Vision and Pattern Recognition · Computer Science 2024-09-27 Muhammad Ahmad , Manuel Mazzara , Salvatore Distifano

High-quality whole-slide scanning is expensive, complex, and time-consuming, thus limiting the acquisition and utilization of high-resolution histopathology images in daily clinical work. Deep learning-based single-image super-resolution…

Image and Video Processing · Electrical Eng. & Systems 2024-11-08 Minghong Duan , Linhao Qu , Zhiwei Yang , Manning Wang , Chenxi Zhang , Zhijian Song

This paper focuses on an accurate and fast interpolation approach for image transformation employed in the design of CNN architectures. Standard Spatial Transformer Networks (STNs) use bilinear or linear interpolation as their…

Computer Vision and Pattern Recognition · Computer Science 2023-07-25 Pourya Shamsolmoali , Masoumeh Zareapoor

Improving the detailed understanding of the underlying properties and functions of biomolecules has recently attracted growing interest, enabled by the possibility of real-space imaging of single, intact macromolecules using Scanning…

Mesoscale and Nanoscale Physics · Physics 2026-03-10 Tim J. Seifert , Dhaneesh Kumar , Markus Etzkorn , Stephan Rauschenbach , Klaus Kern , Kelvin Anggara , Uta Schlickum

Spatial transcriptomics is an emerging technology that aligns histopathology images with spatially resolved gene expression profiling. It holds the potential for understanding many diseases but faces significant bottlenecks such as…

Computer Vision and Pattern Recognition · Computer Science 2024-01-12 Gabriel Mejia , Paula Cárdenas , Daniela Ruiz , Angela Castillo , Pablo Arbeláez

Supervised and unsupervised techniques have demonstrated the potential for temporal interpolation of video data. Nevertheless, most prevailing temporal interpolation techniques hinge on optical flow, which encodes the motion of pixels…

Computer Vision and Pattern Recognition · Computer Science 2023-09-04 Nidhin Harilal , Bri-Mathias Hodge , Aneesh Subramanian , Claire Monteleoni

We introduce Permutation and Structured Perturbation Inference (PSPI), a new problem formulation that abstracts many graph matching tasks that arise in systems biology. PSPI can be viewed as a robust formulation of the permutation inference…

Artificial Intelligence · Computer Science 2021-04-05 Raghvendra Mall , Shameem A. Parambath , Han Yufei , Ting Yu , Sanjay Chawla

Spatial transcriptomics (ST) technologies enable transcriptome-wide gene expression profiling while preserving spatial resolution, offering unprecedented opportunities to uncover complex spatial structures. Due to the ultra-high…

Applications · Statistics 2026-03-11 Changhu Wang , Qiyun Huang , Zihao Chen , Jin Liu , Ruibin Xi