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Survival analysis models the distribution of time until an event of interest, such as discharge from the hospital or admission to the ICU. When a model's predicted number of events within any time interval is similar to the observed number,…

Machine Learning · Computer Science 2021-01-15 Mark Goldstein , Xintian Han , Aahlad Puli , Adler J. Perotte , Rajesh Ranganath

Large data sets often require performing distributed statistical estimation, with a full data set split across multiple machines and limited communication between machines. To study such scenarios, we define and study some refinements of…

Information Theory · Computer Science 2014-06-24 John C. Duchi , Michael I. Jordan , Martin J. Wainwright , Yuchen Zhang

Consider a setting where multiple parties holding sensitive data aim to collaboratively learn population level statistics, but pooling the sensitive data sets is not possible. We propose a framework in which each party shares a…

Machine Learning · Computer Science 2023-08-10 Lukas Prediger , Joonas Jälkö , Antti Honkela , Samuel Kaski

In modern randomized experiments, large-scale data collection increasingly yields rich baseline covariates and auxiliary information from multiple sources. Such information offers opportunities for more precise treatment effect estimation,…

Methodology · Statistics 2026-03-10 Wei Ma , Zeqi Wu , Zheng Zhang

Data integration and sharing maximally enhance the potential for novel and meaningful discoveries. However, it is a non-trivial task as integrating data from multiple sources can put sensitive information of study participants at risk. To…

Cryptography and Security · Computer Science 2020-05-25 Yeongjae Gil , Xiaoqian Jiang , Miran Kim , Junghye Lee

The labor-intensive nature of medical data annotation presents a significant challenge for respiratory disease diagnosis, resulting in a scarcity of high-quality labeled datasets in resource-constrained settings. Moreover, patient privacy…

Machine Learning · Computer Science 2025-07-14 Ming Wang , Zhaoyang Duan , Dong Xue , Fangzhou Liu , Zhongheng Zhang

Survival analysis studies the statistical properties of the time until an event of interest occurs. It has been commonly used to study the effectiveness of medical treatments or the lifespan of a population. However, survival analysis can…

Cryptography and Security · Computer Science 2017-08-28 Thông T. Nguyên , Siu Cheung Hui

Privacy data protection in the medical field poses challenges to data sharing, limiting the ability to integrate data across hospitals for training high-precision auxiliary diagnostic models. Traditional centralized training methods are…

Computer Vision and Pattern Recognition · Computer Science 2024-08-26 Tian Bowen , Xu Zhengyang , Yin Zhihao , Wang Jingying , Yue Yutao

Recent advances in single-cell technologies have advanced our understanding of gene regulation and cellular heterogeneity at single-cell resolution. Single-cell data contain both gene expression levels and the proportion of expressing…

Methodology · Statistics 2026-04-10 Seungjun Ahn , Donald Porchia , Panos Roussos , Maaike van Gerwen , Qing Lu , Zhigang Li

Controlled experiments are widely used in many applications to investigate the causal relationship between input factors and experimental outcomes. A completely randomized design is usually used to randomly assign treatment levels to…

Methodology · Statistics 2026-05-12 Yiou Li , Lulu Kang , Xiao Huang

This work presents the first large-scale neutral benchmark experiment focused on single-event, right-censored, low-dimensional survival data. Benchmark experiments are essential in methodological research to scientifically compare new and…

Machine Learning · Statistics 2026-04-24 Lukas Burk , John Zobolas , Bernd Bischl , Andreas Bender , Marvin N. Wright , Raphael Sonabend

Clinical trial simulation (CTS) is critical in new drug development, providing insight into safety and efficacy while guiding trial design. Achieving realistic outcomes in CTS requires an accurately estimated joint distribution of the…

Methodology · Statistics 2025-05-08 Longwen Shang , Min Tsao , Xuekui Zhang

We study inference for censored survival data where some covariates are distorted by some unknown functions of an observable confounding variable in a multiplicative form. Example of this kind of data in medical studies is the common…

Methodology · Statistics 2020-06-03 Yanyan Liu , Yuanshan Wu , Jing Zhang , Haibo Zhou

Survival analysis is widely used in applications involving sensitive individual-level data, yet differentially private hypothesis testing for right-censored data remains largely undeveloped. We initiate a finite-sample theory of private…

Statistics Theory · Mathematics 2026-05-19 Elly K. H. Hung , Yi Yu

Background: Survival prediction models are often less reliable in clinical groups with limited sample sizes or few outcome events. Target-only models may be unstable, whereas models from larger cohorts may transfer poorly when risk-factor…

Methodology · Statistics 2026-05-18 Junhan Yu , Yurui Chen , Juan Delgado-SanMartin , Dennis Wang , Hong Pan , Doudou Zhou

Many modern statistical analysis and machine learning applications require training models on sensitive user data. Under a formal definition of privacy protection, differentially private algorithms inject calibrated noise into the…

Machine Learning · Statistics 2025-04-01 Yifei Xiong , Nianqiao Phyllis Ju , Sanguo Zhang

Classifiers deployed in high-stakes real-world applications must output calibrated confidence scores, i.e. their predicted probabilities should reflect empirical frequencies. Recalibration algorithms can greatly improve a model's…

Machine Learning · Computer Science 2020-08-25 Rachel Luo , Shengjia Zhao , Jiaming Song , Jonathan Kuck , Stefano Ermon , Silvio Savarese

Organizations interact with the environment and with other organizations, and these interactions constitute an important way of learning and evolution. To overcome the problems that they face during their existence, organizations must…

Applications · Statistics 2020-05-05 Paula Lopes , Pedro Campos , Luis Meira-Machado

The survey experiment is widely used in economics and social sciences to evaluate the effects of treatments or programs. In a standard population-based survey experiment, the experimenter randomly draws experimental units from a target…

Methodology · Statistics 2026-05-11 Pengfei Tian , Jiyang Ren , Yingying Ma

The Kaplan--Meier (KM) estimator, which provides a nonparametric estimate of a survival function for time-to-event data, has wide application in clinical studies, engineering, economics and other fields. The theoretical properties of the KM…

Methodology · Statistics 2020-11-23 Jiaqi Gu , Yiwei Fan , Guosheng Yin
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