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With the development of big data and machine learning, privacy concerns have become increasingly critical, especially when handling heterogeneous datasets containing sensitive personal information. Differential privacy provides a rigorous…

Machine Learning · Statistics 2025-08-08 Ziliang Shen , Caixing Wang , Shaoli Wang , Yibo Yan

In medical research, individual-level patient data provide invaluable information, but the patients' right to confidentiality remains of utmost priority. This poses a huge challenge when estimating statistical models such as linear mixed…

Methodology · Statistics 2025-01-24 Marie Analiz April Limpoco , Christel Faes , Niel Hens

We study a setting where a data holder wishes to share data with a receiver, without revealing certain summary statistics of the data distribution (e.g., mean, standard deviation). It achieves this by passing the data through a…

Cryptography and Security · Computer Science 2023-10-31 Zinan Lin , Shuaiqi Wang , Vyas Sekar , Giulia Fanti

Effective visualization of survival data is essential for clinician interpretation and patient communication. While Kaplan-Meier (KM) plots are widely used, Mean Residual Life (MRL) plots may offer a more intuitive display of prognosis over…

Methodology · Statistics 2025-11-12 Victor Pacifique Rwandarwacu

The analysis of high dimensional survival data is challenging, primarily due to the problem of overfitting which occurs when spurious relationships are inferred from data that subsequently fail to exist in test data. Here we propose a novel…

Statistics Theory · Mathematics 2016-01-28 James E. Barrett , Anthony C. C. Coolen

Non-parametric maximum likelihood estimation encompasses a group of classic methods to estimate distribution-associated functions from potentially censored and truncated data, with extensive applications in survival analysis. These methods,…

Methodology · Statistics 2021-08-05 Justin D. Tubbs , Lane Guolan Chen , Thuan Quoc Thach , Pak C. Sham

Understanding variable dependence, particularly eliciting their statistical properties given a set of covariates, provides the mathematical foundation in practical operations management such as risk analysis and decision-making given…

Methodology · Statistics 2023-09-06 Yunyun Wang , Tatsushi Oka , Dan Zhu

In applications where the study data are collected within cluster units (e.g., patients within transplant centers), it is often of interest to estimate and perform inference on the treatment effects of the cluster units. However, it is…

Applications · Statistics 2023-05-11 Nicholas Hartman , Kevin He

Although the independent censoring assumption is commonly used in survival analysis, it can be violated when the censoring time is related to the survival time, which often happens in many practical applications. To address this issue, we…

Methodology · Statistics 2024-08-28 Huazhen Yu , Lixin Zhang

The pseudo-observations approach has been gaining popularity as a method to estimate covariate effects on censored survival data. It is used regularly to estimate covariate effects on quantities such as survival probabilities, restricted…

Methodology · Statistics 2024-12-06 Yael Travis-Lumer , Micha Mandel , Rebecca A. Betensky

This work considers the problem of Distributed Mean Estimation (DME) over networks with intermittent connectivity, where the goal is to learn a global statistic over the data samples localized across distributed nodes with the help of a…

Information Theory · Computer Science 2023-03-02 Rajarshi Saha , Mohamed Seif , Michal Yemini , Andrea J. Goldsmith , H. Vincent Poor

Kaplan--Meier curves are widely used in medical research to evaluate the performance of biomarkers and predict patient outcomes. These curves are often shown without error bands, and even when error bands are provided, they typically only…

Methodology · Statistics 2025-09-22 Jeffrey Roskes

This paper focuses on the privacy paradigm of providing access to researchers to remotely carry out analyses on sensitive data stored behind firewalls. We address the situation where the analysis demands data from multiple physically…

Methodology · Statistics 2017-10-20 Joshua Snoke , Timothy R. Brick , Aleksandra Slavkovic , Michael D. Hunter

Integrating information from multiple data sources can enable more precise, timely, and generalizable decisions. However, it is challenging to make valid causal inferences using observational data from multiple data sources. For example, in…

Methodology · Statistics 2023-02-08 Larry Han , Yige Li , Bijan A. Niknam , Jose R. Zubizarreta

This paper studies federated learning for nonparametric regression in the context of distributed samples across different servers, each adhering to distinct differential privacy constraints. The setting we consider is heterogeneous,…

Statistics Theory · Mathematics 2024-06-12 T. Tony Cai , Abhinav Chakraborty , Lasse Vuursteen

We introduce a statistical procedure that integrates survival data from multiple biomedical studies, to improve the accuracy of predictions of survival or other events, based on individual clinical and genomic profiles, compared to models…

Applications · Statistics 2020-07-20 Steffen Ventz , Rahul Mazumder , Lorenzo Trippa

Multi-omics data, that is, datasets containing different types of high-dimensional molecular variables (often in addition to classical clinical variables), are increasingly generated for the investigation of various diseases. Nevertheless,…

Machine Learning · Statistics 2020-12-22 Moritz Herrmann , Philipp Probst , Roman Hornung , Vindi Jurinovic , Anne-Laure Boulesteix

It has been proposed that complex populations, such as those that arise in genomics studies, may exhibit dependencies among observations as well as among variables. This gives rise to the challenging problem of analyzing unreplicated…

Machine Learning · Statistics 2018-06-08 Michael Hornstein , Roger Fan , Kerby Shedden , Shuheng Zhou

We propose the use of non-parametric, graph-based tests to assess the distributional balance of covariates in observational studies with multi-valued treatments. Our tests utilize graph structures ranging from Hamiltonian paths that connect…

Methodology · Statistics 2022-08-11 Eric A. Dunipace

We consider the problem of collaborative personalized mean estimation under a privacy constraint in an environment of several agents continuously receiving data according to arbitrary unknown agent-specific distributions. In particular, we…

Machine Learning · Computer Science 2024-12-02 Yauhen Yakimenka , Chung-Wei Weng , Hsuan-Yin Lin , Eirik Rosnes , Jörg Kliewer