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While recent advances in large language models have significantly improved Text-to-SQL and table question answering systems, most existing approaches assume that all query-relevant information is explicitly represented in structured…

Databases · Computer Science 2026-04-06 Nima Shahbazi , Seiji Maekawa , Nikita Bhutani , Estevam Hruschka

Approaches to enhancing data quality (DQ) are classified into two main categories: data- and process-driven. However, prior research has predominantly utilized batch data preprocessing within the data-driven framework, which often proves…

Human-Computer Interaction · Computer Science 2025-07-17 Hyein Hong , Sangbong Yoo , SeokHwan Choi , Jisue Kim , Seongbum Seo , Haneol Cho , Chansoo Kim , Yun Jang

Quantum computing (QC) promises to be a transformative technology with impact on various application domains, such as optimization, cryptography, and material science. However, the technology has a sharp learning curve, and practical…

Liquid Chromatography Mass Spectrometry (LC-MS) is an indispensable analytical technique in proteomics, metabolomics, and other life sciences. While OpenMS provides advanced open-source software for MS data analysis, its complexity can be…

As experiments continue to push the quantum-classical boundary using increasingly complex dynamical systems, the interpretation of experimental data becomes more and more challenging: when the observations are noisy, indirect, and limited,…

Quantum Physics · Physics 2014-01-28 Mankei Tsang

Enrichment of predictive models with new biomolecular markers is an important task in high-dimensional omic applications. Increasingly, clinical studies include several sets of such omics markers available for each patient, measuring…

Quantum machine learning has attracted significant interest in recent years. Most existing approaches, however, are variational in nature and require extensive parameter optimization subroutines. Here, we propose a conceptually distinct…

Quantum Physics · Physics 2026-04-22 Kristina Kirova , Monika Doerfler , Franz Luef , Richard Kueng

Study reproducibility is essential to corroborate, build on, and learn from the results of scientific research but is notoriously challenging in bioinformatics, which often involves large data sets and complex analytic workflows involving…

Quantitative Methods · Quantitative Biology 2023-05-22 Christopher R. Keefe , Matthew R. Dillon , Chloe Herman , Mary Jewell , Colin V. Wood , Evan Bolyen , J. Gregory Caporaso

High-throughput omics profiling advancements have greatly enhanced cancer patient stratification. However, incomplete data in multi-omics integration presents a significant challenge, as traditional methods like sample exclusion or…

Genomics · Quantitative Biology 2024-01-17 Shihao Ma , Andy G. X. Zeng , Benjamin Haibe-Kains , Anna Goldenberg , John E Dick , Bo Wang

Reconfigurable linear optical networks are a key component for the development of optical quantum information processing platforms in the NISQ era and beyond. We report the implementation of such a device based on an innovative design that…

Quantum Physics · Physics 2022-10-21 A. Cavaillès , P. Boucher , L. Daudet , I. Carron , S. Gigan , K. Müller

Optimizing smart grid operations relies on critical decision-making informed by uncertainty quantification, making probabilistic forecasting a vital tool. Designing such forecasting models involves three key challenges: accurate and…

Machine Learning · Computer Science 2024-12-03 Stefan Meisenbacher , Kaleb Phipps , Oskar Taubert , Marie Weiel , Markus Götz , Ralf Mikut , Veit Hagenmeyer

Understanding the emergence of objectivity from the quantum realm has been a long standing issue strongly related to the quantum to classical crossover. Quantum Darwinism provides an answer, interpreting objectivity as consensus between…

Precision medicine fundamentally aims to establish causality between dysregulated biochemical mechanisms and cancer subtypes. Omics-based cancer subtyping has emerged as a revolutionary approach, as different level of omics records the…

Genomics · Quantitative Biology 2023-08-25 Ziwei Yang , Zheng Chen , Yasuko Matsubara , Yasushi Sakurai

We introduce GQA, a new dataset for real-world visual reasoning and compositional question answering, seeking to address key shortcomings of previous VQA datasets. We have developed a strong and robust question engine that leverages scene…

Computation and Language · Computer Science 2019-07-12 Drew A. Hudson , Christopher D. Manning

Benchmarks shape progress in AI research. A useful benchmark should be both difficult and realistic: questions should challenge frontier models while also reflecting real-world usage. Yet, current paradigms face a difficulty-realism…

The connect-fill-run workflow paradigm, widely adopted in mature software engineering, accelerates collaborative development. However, computational chemistry, computational materials science, and computational biology face persistent…

Chemical Physics · Physics 2025-08-12 Jianan Wang , Wenbo Guo , Xin Yue , Minjie Xu , Yueqiang Zheng , Jingxiang Dong , Jiarui Hu , Jian Xia , Chuixiong Wu

PepSIRF is a command-line, module-based open-source software package that facilitates the analysis of data from highly-multiplexed serology assays (e.g., PepSeq or PhIP-Seq). It has nine separate modules in its current release (v1.5.0):…

Quantitative Methods · Quantitative Biology 2022-07-26 Annabelle M. Brown , Evan Bolyen , Isaiah Raspet , John A. Altin , Jason T. Ladner

We present PyMoosh, a Python-based simulation library designed to provide a comprehensive set of numerical tools allowing to compute essentially all optical characteristics of multilayered structures, ranging from reflectance and…

Machine learning (ML) models hold the promise of transforming atomic simulations by delivering quantum chemical accuracy at a fraction of the computational cost. Realization of this potential would enable high-throughout, high-accuracy…

Exploiting the properties of quantum information to the benefit of machine learning models is perhaps the most active field of research in quantum computation. This interest has supported the development of a multitude of software…

Quantum Physics · Physics 2023-10-24 Francesco Di Marcantonio , Massimiliano Incudini , Davide Tezza , Michele Grossi