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Healthcare data are generated in many different formats, which makes it difficult to integrate and reuse across institutions and studies. Standardisation is required to enable consistent large-scale analysis. The OMOP-CDM, developed by the…

Quantitative Methods · Quantitative Biology 2025-11-13 Jacob Desmond , Ryan Wartmann , Chng Wei Lau , Steven Thomas , Paul M. Middleton , Jeewani Anupama Ginige

Accurate multivariate time-series prediction of vital signs and laboratory results is crucial for early intervention and precision medicine in intensive care units (ICUs). However, vital signs are often noisy and exhibit rapid fluctuations,…

Machine Learning · Computer Science 2025-11-26 Wanzhe Xu , Yutong Dai , Yitao Yang , Martin Loza , Weihang Zhang , Yang Cui , Xin Zeng , Sung Joon Park , Kenta Nakai

The enabling of scientific experiments that are embarrassingly parallel, long running and data-intensive into a cloud-based execution environment is a desirable, though complex undertaking for many researchers. The management of such…

Recent developments in single-cell omics technologies have enabled the quantification of molecular profiles in individual cells at an unparalleled resolution. Deep learning, a rapidly evolving sub-field of machine learning, has instilled a…

Genomics · Quantitative Biology 2024-01-17 Manoj M Wagle , Siqu Long , Carissa Chen , Chunlei Liu , Pengyi Yang

Summary: Modern omics experiments now involve multiple conditions and complex designs, producing an increasingly large set of differential expression and functional enrichment analysis results. However, no standardized data structure exists…

Genomics · Quantitative Biology 2026-03-10 Najla Abassi , Lea Schwarz , Edoardo Filippi , Federico Marini

Recently, symbolic computation and computer algebra systems have been successfully applied in systems biology, especially in chemical reaction network theory. One advantage of symbolic computation is its potential for qualitative answers to…

Molecular Networks · Quantitative Biology 2022-01-25 Christoph Lüders , Thomas Sturm , Ovidiu Radulescu

The discovery of disease subtypes is an essential step for developing precision medicine, and disease subtyping via omics data has become a popular approach. While promising, subtypes obtained from existing approaches are not necessarily…

Quantitative Methods · Quantitative Biology 2022-03-01 Lingsong Meng , Dorina Avram , George Tseng , Zhiguang Huo

Omics biomarkers play a pivotal role in personalized medicine by providing molecular-level insights into the etiology of diseases, guiding precise diagnostics, and facilitating targeted therapeutic interventions. Recent advancements in…

Applications · Statistics 2024-02-21 Minhao Yao , Zhonghua Liu

Heterogeneous, interconnected, systems-level, molecular data have become increasingly available and key in precision medicine. We need to utilize them to better stratify patients into risk groups, discover new biomarkers and targets,…

Other Quantitative Biology · Quantitative Biology 2024-05-17 Natasa Przulj , Noel Malod-Dognin

We present a new method for the accurate analysis of the quality-of-service (QoS) properties of component-based systems. Our method takes as input a QoS property of interest and a high-level continuous-time Markov chain (CTMC) model of the…

Software Engineering · Computer Science 2018-05-25 Colin Paterson , Radu Calinescu

This study introduces GreenIQ, an AI-powered deep search platform designed to revolutionise carbon market intelligence through autonomous analysis and automated report generation. Carbon markets operate across diverse regulatory landscapes,…

Omics fusion has emerged as a crucial preprocessing approach in the field of medical image processing, providing significant assistance to several studies. One of the challenges encountered in the integration of omics data is the presence…

Quantitative Methods · Quantitative Biology 2025-02-17 Jiabao Sheng , SaiKit Lam , Jiang Zhang , Yuanpeng Zhang , Jing Cai

Quantum Machine Learning (QML) is a red-hot field that brings novel discoveries and exciting opportunities to resolve, speed up, or refine the analysis of a wide range of computational problems. In the realm of biomedical research and…

Machine Learning · Computer Science 2024-10-04 Mandeep Kaur Saggi , Amandeep Singh Bhatia , Mensah Isaiah , Humaira Gowher , Sabre Kais

Over the years, many subjective and objective quality assessment datasets have been created and made available to the research community. However, there is no standard process for documenting the various aspects of the dataset, such as…

Multimedia · Computer Science 2023-05-04 Nabajeet Barman , Yuriy Reznik , Maria Martini

Many disciplines pose natural-language research questions over large document collections whose answers typically require structured evidence, traditionally obtained by manually designing an annotation schema and exhaustively labeling the…

Computation and Language · Computer Science 2026-04-13 Shahar Levy , Eliya Habba , Reshef Mintz , Barak Raveh , Renana Keydar , Gabriel Stanovsky

Distributed, large-scale quantum computing will need architectures that combine matter-based qubits with photonic links, but today's software stacks target either gate-based chips or linear-optical devices in isolation. We introduce Optyx,…

Blind image quality assessment (BIQA) approaches, while promising for automating image quality evaluation, often fall short in real-world scenarios due to their reliance on a generic quality standard applied uniformly across diverse images.…

Computer Vision and Pattern Recognition · Computer Science 2024-07-17 Nicolas Chahine , Sira Ferradans , Jean Ponce

The emergence of Big Data changed how we approach information systems engineering. Nowadays, when we can use remote sensing techniques for Big Data acquisition, the issues such data introduce are as important as ever. One of those concerns…

Quantum Physics · Physics 2025-12-16 Tomasz Rybotycki , Manish K. Gupta , Piotr Gawron

Symmetric informationally complete measurements are both important building blocks in many quantum information protocols and the seminal example of a generalised, non-orthogonal, quantum measurement. In higher-dimensional systems, these…

Background: Systems biology projects and omics technologies have led to a growing number of biochemical pathway reconstructions. However, mathematical models are still most often created de novo, based on reading the literature and…