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Background: MRI is the modality of choice for cartilage imaging; however, its diagnostic performance is variable and significantly lower than the gold standard diagnostic knee arthroscopy. In recent years, deep learning has been used to…

Computer Vision and Pattern Recognition · Computer Science 2021-06-24 Gergo Merkely , Alireza Borjali , Molly Zgoda , Evan M. Farina , Simon Gortz , Orhun Muratoglu , Christian Lattermann , Kartik M. Varadarajan

Knee Osteoarthritis (KOA) is the third most prevalent Musculoskeletal Disorder (MSD) after neck and back pain. To monitor such a severe MSD, a segmentation map of the femur, tibia and tibiofemoral cartilage is usually accessed using the…

Image and Video Processing · Electrical Eng. & Systems 2024-01-24 Akshay Daydar , Alik Pramanick , Arijit Sur , Subramani Kanagaraj

Domain shift refers to the well known problem that a model trained in one source domain performs poorly when applied to a target domain with different statistics. {Domain Generalization} (DG) techniques attempt to alleviate this issue by…

Machine Learning · Computer Science 2017-10-11 Da Li , Yongxin Yang , Yi-Zhe Song , Timothy M. Hospedales

In a longitudinal clinical registry, different measurement instruments might have been used for assessing individuals at different time points. To combine them, we investigate deep learning techniques for obtaining a joint latent…

Machine Learning · Computer Science 2023-12-04 Maren Hackenberg , Michelle Pfaffenlehner , Max Behrens , Astrid Pechmann , Janbernd Kirschner , Harald Binder

Despite progress in deep learning for Alzheimer's disease (AD) diagnostics, models trained on structural magnetic resonance imaging (sMRI) often do not perform well when applied to new cohorts due to domain shifts from varying scanners,…

Computer Vision and Pattern Recognition · Computer Science 2026-01-12 Zobia Batool , Diala Lteif , Vijaya B. Kolachalama , Huseyin Ozkan , Erchan Aptoula

The problem of domain generalization is to take knowledge acquired from a number of related domains where training data is available, and to then successfully apply it to previously unseen domains. We propose a new feature learning…

Computer Vision and Pattern Recognition · Computer Science 2016-07-28 Muhammad Ghifary , W. Bastiaan Kleijn , Mengjie Zhang , David Balduzzi

The performance of state-of-the-art neural rankers can deteriorate substantially when exposed to noisy inputs or applied to a new domain. In this paper, we present a novel method for fine-tuning neural rankers that can significantly improve…

Information Retrieval · Computer Science 2021-06-01 Xiaofei Ma , Cicero Nogueira dos Santos , Andrew O. Arnold

Deep learning has revolutionized neuroimage analysis by delivering unprecedented speed and accuracy. However, the narrow scope of many training datasets constrains model robustness and generalizability. This challenge is particularly acute…

Image and Video Processing · Electrical Eng. & Systems 2025-12-08 Malte Hoffmann

To develop and evaluate a new deep learning MR denoising method that leverages quantitative noise distribution information from the reconstruction process to improve denoising performance and generalization. This retrospective study trained…

As a powerful technique in medical imaging, image synthesis is widely used in applications such as denoising, super resolution and modality transformation etc. Recently, the revival of deep neural networks made immense progress in the field…

Image and Video Processing · Electrical Eng. & Systems 2021-04-23 Gengyan Zhao , Mary E. Meyerand , Rasmus M. Birn

Despite the impressive advances achieved using deep learning for functional brain activity analysis, the heterogeneity of functional patterns and the scarcity of imaging data still pose challenges in tasks such as identifying neurological…

Image and Video Processing · Electrical Eng. & Systems 2025-05-30 Wenhui Cui , Haleh Akrami , Anand A. Joshi , Richard M. Leahy

Conventional and deep learning-based methods have shown great potential in the medical imaging domain, as means for deriving diagnostic, prognostic, and predictive biomarkers, and by contributing to precision medicine. However, these…

Machine learning algorithms have revolutionized different fields, including natural language processing, computer vision, signal processing, and medical data processing. Despite the excellent capabilities of machine learning algorithms in…

Image and Video Processing · Electrical Eng. & Systems 2022-12-07 Gita Sarafraz , Armin Behnamnia , Mehran Hosseinzadeh , Ali Balapour , Amin Meghrazi , Hamid R. Rabiee

Deep learning models for echocardiography segmentation often struggle to generalise across institutions, scanners, and patient populations, where collecting large, consistently annotated datasets is infeasible. Data augmentation is widely…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Soroush Elyasi , Sara Adibzadeh , Nasim Dadashi Serej , Julie Wall , Massoud Zolgharni

Data augmentation has been widely used to improve generalization in training deep neural networks. Recent works show that using worst-case transformations or adversarial augmentation strategies can significantly improve the accuracy and…

Computer Vision and Pattern Recognition · Computer Science 2022-11-15 Liang Xiao , Jiaolong Xu , Dawei Zhao , Erke Shang , Qi Zhu , Bin Dai

Building accurate Deep Learning (DL) models for brain age prediction is a very relevant topic in neuroimaging, as it could help better understand neurodegenerative disorders and find new biomarkers. To estimate accurate and generalizable…

Image and Video Processing · Electrical Eng. & Systems 2023-03-22 Carlo Alberto Barbano , Benoit Dufumier , Edouard Duchesnay , Marco Grangetto , Pietro Gori

Deep learning models for medical image analysis often suffer from performance degradation when applied to data from different scanners or protocols, a phenomenon known as domain shift. This study investigates this challenge in the context…

Medical Physics · Physics 2025-08-29 Peyman Sharifian , Mohammad Saber Azimi , AliReza Karimian , Hossein Arabi

The biggest challenge in the application of deep learning to the medical domain is the availability of training data. Data augmentation is a typical methodology used in machine learning when confronted with a limited data set. In a…

Image and Video Processing · Electrical Eng. & Systems 2024-03-21 Oleksandr Fedoruk , Konrad Klimaszewski , Aleksander Ogonowski , Rafał Możdżonek

Generative Adversarial Network (GAN)-based synthesis of fat suppressed (FS) MRIs from non-FS proton density sequences has the potential to accelerate acquisition of knee MRIs. However, GANs trained on single-site data have poor…

Image and Video Processing · Electrical Eng. & Systems 2024-04-12 Pranav Kulkarni , Adway Kanhere , Harshita Kukreja , Vivian Zhang , Paul H. Yi , Vishwa S. Parekh

The insertion of deep learning in medical image analysis had lead to the development of state-of-the art strategies in several applications such a disease classification, as well as abnormality detection and segmentation. However, even the…

Image and Video Processing · Electrical Eng. & Systems 2022-02-24 Mauricio Orbes-Arteaga , Thomas Varsavsky , Lauge Sorensen , Mads Nielsen , Akshay Pai , Sebastien Ourselin , Marc Modat , M Jorge Cardoso