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Magnification shift is a major obstacle to robust histopathology classification, because models trained on one imaging scale often generalize poorly to another. Here, we evaluated this problem on the BreaKHis dataset using a strict…

Computer Vision and Pattern Recognition · Computer Science 2026-04-29 Ifeanyi Ezuma , Olusiji Medaiyese

Deep learning models perform best when tested on target (test) data domains whose distribution is similar to the set of source (train) domains. However, model generalization can be hindered when there is significant difference in the…

Computer Vision and Pattern Recognition · Computer Science 2020-08-19 Pulkit Khandelwal , Paul Yushkevich

Knee pain is undoubtedly the most common musculoskeletal symptom that impairs quality of life, confines mobility and functionality across all ages. Knee pain is clinically evaluated by routine radiographs, where the widespread adoption of…

Image and Video Processing · Electrical Eng. & Systems 2022-02-14 Shi Yan , Taghi Ramazanian , Elham Sagheb , Walter K. Kremers , Vipin Chaudhary , Michael Taunton , Hilal Maradit Kremers , Ahmad P. Tafti

Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory disease that results in progressive articular destruction and severe disability. Joint space narrowing (JSN) progression has been regarded as an important indicator for RA…

Image and Video Processing · Electrical Eng. & Systems 2024-04-01 Haolin Wang , Yafei Ou , Wanxuan Fang , Prasoon Ambalathankandy , Naoto Goto , Gen Ota , Masayuki Ikebe , Tamotsu Kamishima

Knee osteoarthritis (OA) is one of the highest disability factors in the world. This musculoskeletal disorder is assessed from clinical symptoms, and typically confirmed via radiographic assessment. This visual assessment done by a…

Image and Video Processing · Electrical Eng. & Systems 2020-08-13 Huy Hoang Nguyen , Simo Saarakkala , Matthew Blaschko , Aleksei Tiulpin

Clinical risk prediction models often fail to be generalized across cohorts because underlying data distributions differ by clinical site, region, demographics, and measurement protocols. This limitation is particularly pronounced in hip…

Two-dimensional (2D) fast spin echo (FSE) techniques play a central role in the clinical magnetic resonance imaging (MRI) of knee joints. Moreover, three-dimensional (3D) FSE provides high-isotropic-resolution magnetic resonance (MR) images…

Image and Video Processing · Electrical Eng. & Systems 2022-12-15 Shutian Zhao , Donal G. Cahill , Siyue Li , Fan Xiao , Thierry Blu , James F Griffith , Weitian Chen

Out-of-distribution (OOD) generalization poses a serious challenge for modern deep learning (DL). OOD data consists of test data that is significantly different from the model's training data. DL models that perform well on in-domain test…

Computer Vision and Pattern Recognition · Computer Science 2023-08-22 Skylar E. Stolte , Kyle Volle , Aprinda Indahlastari , Alejandro Albizu , Adam J. Woods , Kevin Brink , Matthew Hale , Ruogu Fang

Domain generalisation (DG) methods address the problem of domain shift, when there is a mismatch between the distributions of training and target domains. Data augmentation approaches have emerged as a promising alternative for DG. However,…

Machine Learning · Computer Science 2020-12-29 Hoang Son Le , Rini Akmeliawati , Gustavo Carneiro

Deep learning has been used extensively for medical image analysis applications, assuming the training and test data adhere to the same probability distributions. However, a common challenge arises when dealing with medical images generated…

Image and Video Processing · Electrical Eng. & Systems 2024-07-09 Mohd Usama , Emma Nyman , Ulf Naslund , Christer Gronlund

The data consistency for the physical forward model is crucial in inverse problems, especially in MR imaging reconstruction. The standard way is to unroll an iterative algorithm into a neural network with a forward model embedded. The…

Image and Video Processing · Electrical Eng. & Systems 2023-06-28 Guanxiong Luo , Mengmeng Kuang , Peng Cao

Recent studies have demonstrated that noise in stochastic gradient descent (SGD) is closely related to generalization: A larger SGD noise, if not too large, results in better generalization. Since the covariance of the SGD noise is…

Machine Learning · Computer Science 2020-09-29 Takashi Mori , Masahito Ueda

Deep learning has potential to automate screening, monitoring and grading of disease in medical images. Pretraining with contrastive learning enables models to extract robust and generalisable features from natural image datasets,…

Magnetic Resonance Imaging (MRI) is considered the gold standard of medical imaging because of the excellent soft-tissue contrast exhibited in the images reconstructed by the MRI pipeline, which in-turn enables the human radiologist to…

Image and Video Processing · Electrical Eng. & Systems 2023-06-26 Divyam Madaan , Daniel Sodickson , Kyunghyun Cho , Sumit Chopra

Deep learning (DL) has shown promise for faster, high quality accelerated MRI reconstruction. However, supervised DL methods depend on extensive amounts of fully-sampled (labeled) data and are sensitive to out-of-distribution (OOD) shifts,…

A fully-automated deep learning algorithm matched performance of radiologists in assessment of knee osteoarthritis severity in radiographs using the Kellgren-Lawrence grading system. To develop an automated deep learning-based algorithm…

Image and Video Processing · Electrical Eng. & Systems 2023-08-15 Albert Swiecicki , Nianyi Li , Jonathan O'Donnell , Nicholas Said , Jichen Yang , Richard C. Mather , William A. Jiranek , Maciej A. Mazurowski

A major challenge in applying deep learning to medical imaging is the paucity of annotated data. This study demonstrates that synthetic colonoscopy images generated by Generative Adversarial Network (GAN) inversion can be used as training…

Image and Video Processing · Electrical Eng. & Systems 2025-07-02 Mayank Golhar , Taylor L. Bobrow , Saowanee Ngamruengphong , Nicholas J. Durr

In recent years, the focus is on improving the diagnosis of diabetic retinopathy (DR) using machine learning and deep learning technologies. Researchers have explored various approaches, including the use of high-definition medical imaging,…

Computer Vision and Pattern Recognition · Computer Science 2024-07-26 Saideep Kilaru , Kothamasu Jayachandra , Tanishka Yagneshwar , Suchi Kumari

Objective: In this work the potential of non-invasive detection of knee osteoarthritis is investigated using the sounds generated by the knee joint during walking. Methods: The information contained in the time-frequency domain of these…

Audio and Speech Processing · Electrical Eng. & Systems 2020-04-28 Costas Yiallourides , Patrick A. Naylor

In this paper, we propose the Generalized Parametric Contrastive Learning (GPaCo/PaCo) which works well on both imbalanced and balanced data. Based on theoretical analysis, we observe that supervised contrastive loss tends to bias…

Computer Vision and Pattern Recognition · Computer Science 2023-05-30 Jiequan Cui , Zhisheng Zhong , Zhuotao Tian , Shu Liu , Bei Yu , Jiaya Jia
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