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The analysis of fundus images is critical for the early detection and diagnosis of retinal diseases such as Diabetic Retinopathy (DR), Glaucoma, and Age-related Macular Degeneration (AMD). Traditional diagnostic workflows, however, often…

Computer Vision and Pattern Recognition · Computer Science 2025-07-31 Faisal Ahmed

Retinal fundus photography offers a non-invasive way to diagnose and monitor a variety of retinal diseases, but is prone to inherent quality glitches arising from systemic imperfections or operator/patient-related factors. However,…

Image and Video Processing · Electrical Eng. & Systems 2024-09-13 Vamsi Krishna Vasa , Peijie Qiu , Wenhui Zhu , Yujian Xiong , Oana Dumitrascu , Yalin Wang

We describe a new approach to automated Glaucoma detection in 3D Spectral Domain Optical Coherence Tomography (OCT) optic nerve scans. First, we gathered a unique and diverse multi-ethnic dataset of OCT scans consisting of glaucoma and…

This study evaluated generative methods to potentially mitigate AI bias when diagnosing diabetic retinopathy (DR) resulting from training data imbalance, or domain generalization which occurs when deep learning systems (DLS) face concepts…

Artificial Intelligence · Computer Science 2020-12-03 Philippe Burlina , Neil Joshi , William Paul , Katia D. Pacheco , Neil M. Bressler

Diabetic Retinopathy (DR) is a serious microvascular complication of diabetes, and one of the leading causes of vision loss worldwide. Although automated detection and grading, with Deep Learning (DL), can reduce the burden on…

Image and Video Processing · Electrical Eng. & Systems 2026-04-06 Shramana Dey , Zahir Khan , T. A. PramodKumar , B. Uma Shankar , Ashis K. Dhara , Ramachandran Rajalakshmi , Rajiv Raman , Sushmita Mitra

Glaucoma leads to permanent vision disability by damaging the optical nerve that transmits visual images to the brain. The fact that glaucoma does not show any symptoms as it progresses and cannot be stopped at the later stages, makes it…

Image and Video Processing · Electrical Eng. & Systems 2021-09-29 Ozer Can Devecioglu , Junaid Malik , Turker Ince , Serkan Kiranyaz , Eray Atalay , Moncef Gabbouj

Technological advances in artificial intelligence (AI) have enabled the development of large vision language models (LVLMs) that are trained on millions of paired image and text samples. Subsequent research efforts have demonstrated great…

Computation and Language · Computer Science 2024-11-28 Kalina P. Slavkova , Melanie Traughber , Oliver Chen , Robert Bakos , Shayna Goldstein , Dan Harms , Bradley J. Erickson , Khan M. Siddiqui

Accurate dental diagnosis is essential for oral healthcare, yet many individuals lack access to timely professional evaluation. Existing AI-based methods primarily treat diagnosis as a visual pattern recognition task and do not reflect the…

Diabetic retinopathy (DR) is the most common form of diabetic eye disease. Retinopathy can affect all diabetic patients and becomes particularly dangerous, increasing the risk of blindness, if it is left untreated. The success rate of its…

Computer Vision and Pattern Recognition · Computer Science 2019-02-11 Oindrila Saha , Rachana Sathish , Debdoot Sheet

Adaptive medical AI models often face performance drops in dynamic clinical environments due to data drift. We propose an autonomous continuous monitoring and data integration framework that maintains robust performance over time. Focusing…

Computer Vision and Pattern Recognition · Computer Science 2026-04-13 Mohammad Daouk , Jan Ulrich Becker , Neeraja Kambham , Anthony Chang , Chandra Mohan , Hien Van Nguyen

Choroidal nevi are common benign pigmented lesions in the eye, with a small risk of transforming into melanoma. Early detection is critical to improving survival rates, but misdiagnosis or delayed diagnosis can lead to poor outcomes.…

Computer Vision and Pattern Recognition · Computer Science 2026-04-16 Mohammadmahdi Eshragh , Emad A. Mohammed , Behrouz Far , Ezekiel Weis , Carol L Shields , Sandor R Ferenczy , Trafford Crump

Retinal fundus images are widely used for the clinical screening and diagnosis of eye diseases. However, fundus images captured by operators with various levels of experience have a large variation in quality. Low-quality fundus images…

Image and Video Processing · Electrical Eng. & Systems 2020-12-10 Ziyi Shen , Huazhu Fu , Jianbing Shen , Ling Shao

The application of Artificial Intelligence in the medical market brings up increasing concerns but aids in more timely diagnosis of silent progressing diseases like Diabetic Retinopathy. In order to diagnose Diabetic Retinopathy (DR),…

Image and Video Processing · Electrical Eng. & Systems 2023-10-18 Sharan Subramanian , Leilani H. Gilpin

Purpose: To develop an open-source, fully-automatic deep learning algorithm, DeepGPET, for choroid region segmentation in optical coherence tomography (OCT) data. Methods: We used a dataset of 715 OCT B-scans (82 subjects, 115 eyes) from 3…

Glaucoma is a leading cause of irreversible blindness, but early detection can significantly improve treatment outcomes. Traditional diagnostic methods are often invasive and require specialized equipment. In this work, we present a deep…

Computer Vision and Pattern Recognition · Computer Science 2025-06-30 Rishiraj Paul Chowdhury , Nirmit Shekar Karkera

Recent reasoning based medical MLLMs have made progress in generating step by step textual reasoning chains. However, they still struggle with complex tasks that necessitate dynamic and iterative focusing on fine-grained visual regions to…

Artificial Intelligence · Computer Science 2025-12-17 Yankai Jiang , Yujie Zhang , Peng Zhang , Yichen Li , Jintai Chen , Xiaoming Shi , Shihui Zhen

Fundus imaging such as CFP, OCT and UWF is crucial for the early detection of retinal anomalies and diseases. Fundus image understanding, due to its knowledge-intensive nature, poses a challenging vision-language task. An emerging approach…

Computer Vision and Pattern Recognition · Computer Science 2026-04-10 Yuchuan Deng , Qijie Wei , Kaiheng Qian , Jiazhen Liu , Zijie Xin , Bangxiang Lan , Jingyu Liu , Jianfeng Dong , Xirong Li

Medical artificial intelligence (AI) systems, particularly multimodal vision-language models (VLM), often exhibit intersectional biases where models are systematically less confident in diagnosing marginalised patient subgroups. Such bias…

Computer Vision and Pattern Recognition · Computer Science 2025-12-25 Yupeng Zhang , Adam G. Dunn , Usman Naseem , Jinman Kim

Current deep learning models are mostly task specific and lack a user-friendly interface to operate. We present Meta-EyeFM, a multi-function foundation model that integrates a large language model (LLM) with vision foundation models (VFMs)…

In the last decades, large datasets of fundus photographs have been collected in diabetic retinopathy (DR) screening networks. Through deep learning, these datasets were used to train automatic detectors for DR and a few other frequent…

Computer Vision and Pattern Recognition · Computer Science 2020-02-11 Gwenolé Quellec , Mathieu Lamard , Pierre-Henri Conze , Pascale Massin , Béatrice Cochener