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Early identification of patients at risk of cardiovascular diseases (CVD) is crucial for effective preventive care, reducing healthcare burden, and improving patients' quality of life. This study demonstrates the potential of retinal…

Image and Video Processing · Electrical Eng. & Systems 2024-10-21 Cynthia Maldonado-Garcia , Arezoo Zakeri , Alejandro F Frangi , Nishant Ravikumar

Training models with robust group fairness properties is crucial in ethically sensitive application areas such as medical diagnosis. Despite the growing body of work aiming to minimise demographic bias in AI, this problem remains…

Computer Vision and Pattern Recognition · Computer Science 2024-01-18 Raman Dutt , Ondrej Bohdal , Sotirios A. Tsaftaris , Timothy Hospedales

Generalist Medical AI (GMAI) systems have demonstrated expert-level performance in biomedical perception tasks, yet their clinical utility remains limited by inadequate multi-modal explainability and suboptimal prognostic capabilities.…

Computer Vision and Pattern Recognition · Computer Science 2025-05-13 Honglong Yang , Shanshan Song , Yi Qin , Lehan Wang , Haonan Wang , Xinpeng Ding , Qixiang Zhang , Bodong Du , Xiaomeng Li

The diagnosis of oral diseases presents a problematic clinical challenge, characterized by a wide spectrum of pathologies with overlapping symptomatology. To address this, we developed Clinical Semantic Intelligence (CSI), a novel…

Artificial Intelligence · Computer Science 2025-07-22 Mohammad Mashayekhi , Sara Ahmadi Majd , Arian AmirAmjadi , Parsa Hosseini

Retinopathy of Prematurity (ROP) is a potentially blinding eye disorder because of damage to the eye's retina which can affect babies born prematurely. Screening of ROP is essential for early detection and treatment. This is a laborious and…

Image and Video Processing · Electrical Eng. & Systems 2024-06-18 Sajid Rahim , Kourosh Sabri , Anna Ells , Alan Wassyng , Mark Lawford , Linyang Chu , Wenbo He

Despite its high prevalence, anemia is often undetected due to the invasiveness and cost of screening and diagnostic tests. Though some non-invasive approaches have been developed, they are less accurate than invasive methods, resulting in…

Computer Vision and Pattern Recognition · Computer Science 2020-06-03 Akinori Mitani , Yun Liu , Abigail Huang , Greg S. Corrado , Lily Peng , Dale R. Webster , Naama Hammel , Avinash V. Varadarajan

A variety of vision ailments are associated with geographic atrophy (GA) in the foveal region of the eye. In current clinical practice, the ophthalmologist manually detects potential presence of such GA based on fundus autofluorescence…

The growing burden of myopia and retinal diseases necessitates more accessible and efficient eye screening solutions. This study presents a compact, dual-function optical device that integrates fundus photography and refractive error…

Image and Video Processing · Electrical Eng. & Systems 2025-04-29 Boyuan Peng , Jiaju Chen , Yiwei Zhang , Cuiyi Peng , Junyang Li , Jiaming Deng , Peiwu Qin

Ocular diseases, including diabetic retinopathy and glaucoma, present a significant public health challenge due to their high prevalence and potential for causing vision impairment. Early and accurate diagnosis is crucial for effective…

Image and Video Processing · Electrical Eng. & Systems 2025-01-14 Anirudh Prabhakaran , YeKun Xiao , Ching-Yu Cheng , Dianbo Liu

The rapid advancement of artificial intelligence (AI) in healthcare imaging has revolutionized diagnostic medicine and clinical decision-making processes. This work presents an intelligent multimodal framework for medical image analysis…

Image and Video Processing · Electrical Eng. & Systems 2026-04-20 Samer Al-Hamadani

Artificial intelligence (AI) has demonstrated significant success in automating the detection of glomeruli, the key functional units of the kidney, from whole slide images (WSIs) in kidney pathology. However, existing open-source tools are…

Computer Vision and Pattern Recognition · Computer Science 2025-09-11 Jialin Yue , Tianyuan Yao , Ruining Deng , Siqi Lu , Junlin Guo , Quan Liu , Mengmeng Yin , Juming Xiong , Haichun Yang , Yuankai Huo

Objective: To validate and compare the performance of eight available deep learning architectures in grading the severity of glaucoma based on color fundus images. Materials and Methods: We retrospectively collected a dataset of 5978 fundus…

Computer Vision and Pattern Recognition · Computer Science 2018-11-01 Yi Zhen , Lei Wang , Han Liu , Jian Zhang , Jiantao Pu

Optical Coherence Tomography (OCT) provides valuable insights in ophthalmology, cardiology, and neurology due to high-resolution, cross-sectional images of the retina. One critical task for ophthalmologists using OCT is delineation of…

Image and Video Processing · Electrical Eng. & Systems 2025-05-21 Samuel T. M. Ball

Diabetic retinopathy (DR) is a leading cause of blindness worldwide and a common complication of diabetes. As two different imaging tools for DR grading, color fundus photography (CFP) and infrared fundus photography (IFP) are…

Image and Video Processing · Electrical Eng. & Systems 2024-11-04 Fan Xiao , Junlin Hou , Ruiwei Zhao , Rui Feng , Haidong Zou , Lina Lu , Yi Xu , Juzhao Zhang

Medical image classification is a core task in computer-aided diagnosis (CAD), playing a pivotal role in early disease detection, treatment planning, and patient prognosis assessment. In ophthalmic practice, fluorescein fundus angiography…

Computer Vision and Pattern Recognition · Computer Science 2026-03-11 Zhuonan Wang , Wenjie Yan , Wenqiao Zhang , Xiaohui Song , Jian Ma , Ke Yao , Yibo Yu , Beng Chin Ooi

The increasing prevalence of retinal diseases poses a significant challenge to the healthcare system, as the demand for ophthalmologists surpasses the available workforce. This imbalance creates a bottleneck in diagnosis and treatment,…

Image and Video Processing · Electrical Eng. & Systems 2025-09-17 Jia-Hong Huang

Color fundus image (CFI) bounds detection and contrast enhancement are fundamental tasks in automatic CFI analysis. We present an open-source algorithm, published as a Python package, to automatically extract parametric bounds from color…

Other Quantitative Biology · Quantitative Biology 2025-12-19 Jose Vargas Quiros , Bart Liefers , Karin van Garderen , Eyened Reading Center , Caroline Klaver

Artificial intelligence (AI) has shown great promise in revolutionizing the field of digital health by improving disease diagnosis, treatment, and prevention. This paper describes the Health Guardian platform, a non-commercial, scientific…

Systems and Control · Electrical Eng. & Systems 2023-10-04 Vince S. Siu , Kuan Yu Hsieh , Italo Buleje , Takashi Itoh , Tian Hao , Ben Civjan , Nigel Hinds , Bing Dang , Jeffrey L. Rogers , Bo Wen

Vision impairment and blindness are a major global health challenge where gaps in the ophthalmology workforce limit access to specialist care. We evaluate AMIE, a medically fine-tuned conversational system based on Gemini with integrated…

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