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This paper describes the algorithm and examines the performance of an IMRT beam-angle optimization (BAO) system. In this algorithm successive sets of beam angles are selected from a set of predefined directions using a fast simulated…

Medical Physics · Physics 2009-11-10 David Djajaputra , Qiuwen Wu , Yan Wu , Radhe Mohan

This paper presents an efficient Mixed-Integer Nonlinear Programming (MINLP) formulation for systems with discrete control inputs under dwell time constraints. By viewing such systems as a switched system, the problem is decomposed into a…

Optimization and Control · Mathematics 2025-01-10 Ramin Abbasi-Esfeden , Armin Nurkanovic , Moritz Diehl , Panagiotis Patrinos , Jan Swevers

Almost climate neutral buildings are one of the core goals in terms of sustainability. Beside the support of the necessary design decisions for an integrated, interoperable, ecological and economical operation of building energy systems,…

Systems and Control · Electrical Eng. & Systems 2019-10-17 Armin Wolf

Massive multiple-input multiple-output (MIMO) has gained widespread popularity in recent years due to its ability to increase data rates, improve signal quality, and provide better coverage in challenging environments. In this paper, we…

Networking and Internet Architecture · Computer Science 2023-10-31 Yuhong Huang , Wenxin Li , Chengkang Pan , Shuai Hou , Xian Lu , Chunfeng Cui , Jingwei Wen , Jiaqi Xu , Chongyu Cao , Yin Ma , Hai Wei , Kai Wen

Simultaneous wireless information and power transfer (SWIPT) is anticipated to have great applications in fifth-generation (5G) and beyond communication systems. In this paper, we address the energy efficiency (EE) optimization problem for…

Information Theory · Computer Science 2017-10-24 Jie Tang , Daniel K. C. So , Arman Shojaeifard , Kai-Kit Wong

In this paper, we consider the (global and sum) energy efficiency optimization problem in downlink multi-input multi-output multi-cell systems, where all users suffer from multi-user interference. This is a challenging problem due to…

Optimization and Control · Mathematics 2019-09-04 Yang Yang , Marius Pesavento , Symeon Chatzinotas , Björn Ottersten

A new delivery option for cancer centers equipped with linear accelerators fitted with multi-leaf collimators (MLC) -- i.e. centers which can perform intensity modulated radiation therapy (IMRT) -- is rotational delivery. In rotational…

Medical Physics · Physics 2009-10-27 David Craft , Thomas Bortfeld

The high precision and conformity of intensity-modulated particle therapy (IMPT) comes at the cost of susceptibility to treatment uncertainties in particle range and patient set-up. Dose uncertainty quantification and mitigation, which is…

Medical Physics · Physics 2021-11-17 Pia Stammer , Lucas Burigo , Oliver Jäkel , Martin Frank , Niklas Wahl

Energy system optimization models are increasing in scope and resolution, yielding large and challenging linear programs. For a long time, the standard way to address such problems has relied on shared-memory interior-point methods (IPM),…

Optimization and Control · Mathematics 2026-05-07 Janina Zittel , Annika Buchholz , Michael Bussieck , Frederik Fiand , Thorsten Koch , Lukas Mehl , Niels Lindner , Manuel Wetzel

Mobile edge computing (MEC) is considered as an efficient method to relieve the computation burden of mobile devices. In order to reduce the energy consumption and time delay of mobile devices (MDs) in MEC, multiple users multiple input and…

Signal Processing · Electrical Eng. & Systems 2020-01-07 Changfeng Ding , Jun-Bo Wang , Ming Cheng , Chuanwen Chang , Jin-Yuan Wang , Min Lin

The optimal selection, sizing, and location of small-scale technologies within a grid-connected distributed energy system (DES) can contribute to reducing carbon emissions, consumer costs, and network imbalances. This is the first study to…

Optimization and Control · Mathematics 2022-09-30 Ishanki De Mel , Oleksiy V. Klymenko , Michael Short

We consider mixed-integer optimal control problems with combinatorial constraints that couple over time such as minimum dwell times. We analyze a lifting and decomposition approach into a mixed-integer optimal control problem without…

Optimization and Control · Mathematics 2021-04-21 Simone Göttlich , Falk M. Hante , Andreas Potschka , Lars Schewe

Purpose: To evaluate automated multicriteria optimization (MCO)-- designed for intensity modulated radiation therapy (IMRT), but invoked with limited segmentation -- to efficiently produce high quality 3D conformal treatment (3D-CRT) plans.…

Medical Physics · Physics 2014-02-03 Fazal Khan , David Craft

Operation management of nuclear power plants consists of several computationally hard problems. Searching for an in-core fuel loading pattern is among them. The main challenge of this combinatorial optimization problem is the exponential…

The widespread adoption of on-board volumetric imaging in cancer radiotherapy has stimulated research efforts to develop online adaptive radiotherapy techniques to handle the inter-fraction variation of the patient's geometry. Such efforts…

Medical Physics · Physics 2015-05-14 Chunhua Men , Xuejun Gu , Dongju Choi , Amitava Majumdar , Ziyi Zheng , Klaus Mueller , Steve B. Jiang

In-memory computing (IMC) has been shown to be a promising approach for solving binary optimization problems while significantly reducing energy and latency. Building on the advantages of parallel computation, we propose an IMC-compatible…

In the present article we propose a mixed-integer approximation of adjustable-robust optimization (ARO) problems, that have both, continuous and discrete variables on the lowest level. As these trilevel problems are notoriously hard to…

Optimization and Control · Mathematics 2023-10-11 Jan Kronqvist , Boda Li , Jan Rolfes

Purpose: The importance of robust proton treatment planning to mitigate the impact of uncertainty is well understood. However, its computational cost grows with the number of uncertainty scenarios, prolonging the treatment planning process.…

Medical Physics · Physics 2023-05-01 Anqi Fu , Vicki T. Taasti , Masoud Zarepisheh

In light of the increasing coupling between electricity and gas networks, this paper introduces two novel iterative methods for efficiently solving the multiperiod optimal electricity and gas flow (MOEGF) problem. The first is an iterative…

Optimization and Control · Mathematics 2021-06-28 Sleiman Mhanna , Isam Saedi , Pierluigi Mancarella

Due to critical environmental issues, the power systems have to accommodate a significant level of penetration of renewable generation which requires smart approaches to the power grid control. Associated optimal control problems are…

Optimization and Control · Mathematics 2020-01-30 Juraj Kardos , Drosos Kourounis , Olaf Schenk