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Dual-energy computed tomography (DECT) is a promising technology that has shown a number of clinical advantages over conventional X-ray CT, such as improved material identification, artifact suppression, etc. For proton therapy treatment…

Intensity-modulated proton therapy (IMPT) employs proton radiation rather than conventional X-rays to treat cancerous tumors. This approach offers significant advantages by minimizing the radiation exposure of surrounding healthy tissue,…

In the treatment plan optimization for intensity modulated radiation therapy (IMRT), dose-deposition coefficient (DDC) matrix is often pre-computed to parameterize the dose contribution to each voxel in the volume of interest from each…

Medical Physics · Physics 2013-03-15 Zhen Tian , Masoud Zarepisheh , Xun Jia , Steve B. Jiang

Objective. As proton arc therapy (PAT) approaches clinical implementation, optimizing treatment plans for this innovative delivery modality remains challenging, especially in addressing arc delivery time. Existing algorithms for minimizing…

Medical Physics · Physics 2024-10-11 S. Wuyckens , G. Janssens , M. Chocan Vera , J. Sundstrom , D. Di Perri , E. Sterpin , K. Souris , J. A. Lee

To accurately verify the dose of intensity-modulated radiation therapy (IMRT), we have used a global optimization method to investigate a new dose-verification algorithm. In practical application of this quality assurance (QA) procedure,…

Medical Physics · Physics 2007-05-23 Dong Hyun Park , Sung-Yong Park , Dahl Park , Tae-Hyun Kim , Kyung Hwan Shin , Dae Yong Kim , Kwan-Ho Cho

In radiation therapy, mathematical methods have been used for optimizing treatment planning for delivery of sufficient dose to the cancerous cells while keeping the dose to critical surrounding structures minimal. This optimization problem…

Medical Physics · Physics 2015-06-16 Hamed Yarmand , David Craft

Due to the unique physical-layer characteristics associated with MIMO and cognitive radio (CR), the network performance is tightly coupled with mechanisms at the physical, link, network, and transport layers. In this paper, we consider an…

Networking and Internet Architecture · Computer Science 2016-11-17 Weiqiang Xu , Wenchu Yuan , Qingjiang Shi , Xiaodong Wang , Yake Zhang

We propose a method to solve online mixed-integer optimization (MIO) problems at very high speed using machine learning. By exploiting the repetitive nature of online optimization, we are able to greatly speedup the solution time. Our…

Optimization and Control · Mathematics 2021-03-24 Dimitris Bertsimas , Bartolomeo Stellato

Purpose: Respiratory motion and the interplay effect cause the dose delivered to a patient with spot-scanned proton therapy to differ from the dose planned for during optimization. A new 4D robust optimization methodology was developed…

This paper proposes an iterative method to solve Mixed-Integer Optimal Control Problems arising from systems with switched dynamics. The so-called relaxed problem plays a central role within this context. Through a numerical example, it is…

Optimization and Control · Mathematics 2025-12-09 Ramin Abbasi-Esfeden , Wim Van Roy , Jan Swevers

Purpose: Intensity-modulated proton therapy (IMPT) offers precise tumor coverage while sparing organs at risk (OARs) in head and neck (H&N) cancer. However, its sensitivity to anatomical changes requires frequent adaptation through online…

We propose the use of mixing strategies to accelerate the convergence of the common iterative algorithms utilized in Quantum Optimal Control Theory (QOCT). We show how the non-linear equations of QOCT can be viewed as a "fixed-point"…

Computational Physics · Physics 2009-03-31 Alberto Castro , E. K. U. Gross

The Internet of Things paradigm envisages the presence of many battery-powered sensors and this entails the design of energy-aware protocols. Source coding techniques allow to save some energy by compressing the packets sent over the…

Information Theory · Computer Science 2017-02-14 Alessandro Biason , Chiara Pielli , Andrea Zanella , Michele Zorzi

In the past decades mathematical optimization has found its way into radiation therapy and has made profound practice changing impact. Today, virtually all advanced treatment delivery methods, such as IMRT, VMAT, tomotherapy, LDR/HDR…

Medical Physics · Physics 2018-10-31 Bram L. Gorissen , Jan Unkelbach , Thomas R. Bortfeld

Recent studies have shown that multi-step optimization based on Model Predictive Control (MPC) can effectively coordinate the increasing number of distributed renewable energy and storage resources in the power system. However, the…

Distributed, Parallel, and Cluster Computing · Computer Science 2016-06-02 Junyao Guo , Gabriela Hug , Ozan Tonguz

In this paper, we develop a framework to maximize the network energy efficiency (EE) by optimizing joint user-base station~(BS) association,~subchannel assignment, and power control considering an in-band full-duplex (IBFD)-enabled…

Signal Processing · Electrical Eng. & Systems 2020-10-21 Sheyda Zarandi , Ata Khalili , Mehdi Rasti , Hina Tabassum

The problem of joint power and sub-channel allocation to maximize energy efficiency (EE) and spectral efficiency (SE) simultaneously in in-band full-duplex (IBFD) orthogonal frequency-division multiple access (OFDMA) network is addressed…

Information Theory · Computer Science 2020-03-02 Ata Khalili , Sheyda Zarandi , Mehdi Rasti , Ekram Hossain

In recent years, volumetric modulated arc therapy (VMAT) has been becoming a more and more important radiation technique widely used in clinical application for cancer treatment. One of the key problems in VMAT is treatment plan…

Medical Physics · Physics 2016-01-06 Yu Yang , Bin Dong , Zaiwen Wen

Constrained convex optimization problems arise naturally in many real-world applications. One strategy to solve them in an approximate way is to translate them into a sequence of convex feasibility problems via the recently developed level…

Optimization and Control · Mathematics 2019-04-30 E. Bonacker , A. Gibali , K. -H. Küfer

To improve the cellular energy efficiency, without sacrificing quality-of-service (QoS) at the users, the network topology must be densified to enable higher spatial reuse. We analyze a combination of two densification approaches, namely…

Information Theory · Computer Science 2013-10-22 Emil Björnson , Marios Kountouris , Mérouane Debbah