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Motivated by the growing interest in representation learning approaches that uncover the latent structure of high-dimensional data, this work proposes new algorithms for reconstruction-based manifold learning within Reproducing-Kernel…

Machine Learning · Computer Science 2026-05-07 Enrique Feito-Casares , Francisco M. Melgarejo-Meseguer , José-Luis Rojo-Álvarez

Vision-and-language reasoning requires an understanding of visual concepts, language semantics, and, most importantly, the alignment and relationships between these two modalities. We thus propose the LXMERT (Learning Cross-Modality Encoder…

Computation and Language · Computer Science 2019-12-05 Hao Tan , Mohit Bansal

General-purpose pretrained sentence encoders such as BERT are not ideal for real-world conversational AI applications; they are computationally heavy, slow, and expensive to train. We propose ConveRT (Conversational Representations from…

Computation and Language · Computer Science 2020-04-30 Matthew Henderson , Iñigo Casanueva , Nikola Mrkšić , Pei-Hao Su , Tsung-Hsien Wen , Ivan Vulić

In the genome biology research, regulatory genome modeling is an important topic for many regulatory downstream tasks, such as promoter classification, transaction factor binding sites prediction. The core problem is to model how regulatory…

Genomics · Quantitative Biology 2021-11-04 Shentong Mo , Xi Fu , Chenyang Hong , Yizhen Chen , Yuxuan Zheng , Xiangru Tang , Zhiqiang Shen , Eric P Xing , Yanyan Lan

Gene regulation is a dynamic process that connects genotype and phenotype. Given the difficulty of physically mapping mammalian gene circuitry, we require new computational methods to learn regulatory rules. Natural language is a valuable…

Quantitative Methods · Quantitative Biology 2022-10-27 William Connell , Umair Khan , Michael J. Keiser

Pre-trained model representations have demonstrated state-of-the-art performance in speech recognition, natural language processing, and other applications. Speech models, such as Bidirectional Encoder Representations from Transformers…

Audio and Speech Processing · Electrical Eng. & Systems 2023-03-07 Vikramjit Mitra , Vasudha Kowtha , Hsiang-Yun Sherry Chien , Erdrin Azemi , Carlos Avendano

Recently, the bidirectional encoder representations from transformers (BERT) model has attracted much attention in the field of natural language processing, owing to its high performance in language understanding-related tasks. The BERT…

Machine Learning · Computer Science 2020-04-16 Kazuki Miyazawa , Tatsuya Aoki , Takato Horii , Takayuki Nagai

Fine-tuning pre-trained transformers is a powerful technique for enhancing the performance of base models on specific tasks. From early applications in models like BERT to fine-tuning Large Language Models (LLMs), this approach has been…

Computation and Language · Computer Science 2025-02-25 Suneel Nadipalli

Distinguishing the rare "driver" mutations that fuel cancer progression from the vast background of "passenger" mutations in the non-coding genome is a fundamental challenge in cancer biology. A primary mechanism that non-coding driver…

Genomics · Quantitative Biology 2025-10-01 David Laub , Ethan Armand , Arda Pekis , Zekai Chen , Irsyad Adam , Shaun Porwal , Bing Ren , Kevin Brown , Hannah Carter

Fine-tuned Bidirectional Encoder Representations from Transformers (BERT)-based sequence classification models have proven to be effective for detecting Alzheimer's Disease (AD) from transcripts of human speech. However, previous research…

Computation and Language · Computer Science 2020-11-13 Aparna Balagopalan , Jekaterina Novikova

Transformers have gained increasing popularity in a wide range of applications, including Natural Language Processing (NLP), Computer Vision and Speech Recognition, because of their powerful representational capacity. However, harnessing…

Numerous code changes are made by developers in their daily work, and a superior representation of code changes is desired for effective code change analysis. Recently, Hoang et al. proposed CC2Vec, a neural network-based approach that…

Software Engineering · Computer Science 2023-09-28 Xin Zhou , Bowen Xu , DongGyun Han , Zhou Yang , Junda He , David Lo

Currently, this paper is under review in IEEE. Transformers have intrigued the vision research community with their state-of-the-art performance in natural language processing. With their superior performance, transformers have found their…

Computer Vision and Pattern Recognition · Computer Science 2022-10-05 Preetam Ghosh , Swalpa Kumar Roy , Bikram Koirala , Behnood Rasti , Paul Scheunders

Transformer-based models are widely used in natural language understanding (NLU) tasks, and multimodal transformers have been effective in visual-language tasks. This study explores distilling visual information from pretrained multimodal…

Computation and Language · Computer Science 2022-05-04 Chan-Jan Hsu , Hung-yi Lee , Yu Tsao

Due to limitations such as geographic, physical, or economic factors, collected seismic data often have missing traces. Traditional seismic data reconstruction methods face the challenge of selecting numerous empirical parameters and…

Geophysics · Physics 2026-01-09 Shuang Wang , Fei Deng , Peifan Jiang , Zezheng Ni , Bin Wang

Interpretability of deep learning is widely used to evaluate the reliability of medical imaging models and reduce the risks of inaccurate patient recommendations. For models exceeding human performance, e.g. predicting RNA structure from…

Quantitative Methods · Quantitative Biology 2022-08-31 Mara Graziani , Niccolò Marini , Nicolas Deutschmann , Nikita Janakarajan , Henning Müller , María Rodríguez Martínez

Machine learning methods have recently achieved high-performance in biomedical text analysis. However, a major bottleneck in the widespread application of these methods is obtaining the required large amounts of annotated training data,…

Machine Learning · Computer Science 2019-12-06 Xing Meng , Craig H. Ganoe , Ryan T. Sieberg , Yvonne Y. Cheung , Saeed Hassanpour

We consider the task of unsupervised extraction of meaningful latent representations of speech by applying autoencoding neural networks to speech waveforms. The goal is to learn a representation able to capture high level semantic content…

Machine Learning · Computer Science 2019-09-12 Jan Chorowski , Ron J. Weiss , Samy Bengio , Aäron van den Oord

With the recent successful adaptation of transformers to the vision domain, particularly when trained in a self-supervised fashion, it has been shown that vision transformers can learn impressive object-reasoning-like behaviour and features…

Computer Vision and Pattern Recognition · Computer Science 2022-10-26 Oscar Vikström , Alexander Ilin

To improve the accessibility of smart devices and to simplify their usage, building models which understand user interfaces (UIs) and assist users to complete their tasks is critical. However, unique challenges are proposed by UI-specific…

Computer Vision and Pattern Recognition · Computer Science 2021-08-11 Chongyang Bai , Xiaoxue Zang , Ying Xu , Srinivas Sunkara , Abhinav Rastogi , Jindong Chen , Blaise Aguera y Arcas