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The dominant probing approaches rely on the zero-shot performance of image-text matching tasks to gain a finer-grained understanding of the representations learned by recent multimodal image-language transformer models. The evaluation is…
To achieve deep natural language understanding, syntactic constituent parsing plays a crucial role and is widely required by many artificial intelligence systems for processing both text and speech. A recent approach involves using standard…
Variant calling refinement is crucial for distinguishing true genetic variants from technical artifacts in high-throughput sequencing data. Manual review is time-consuming while heuristic filtering often lacks optimal solutions. Traditional…
This thesis focuses on representation learning for sequence data over time or space, aiming to improve downstream sequence prediction tasks by using the learned representations. Supervised learning has been the most dominant approach for…
Pre-trained and fine-tuned transformer models like BERT and T5 have improved the state of the art in ad-hoc retrieval and question-answering, but not as yet in high-recall information retrieval, where the objective is to retrieve…
Genome modeling conventionally treats gene sequence as a language, reflecting its structured motifs and long-range dependencies analogous to linguistic units and organization principles such as words and syntax. Recent studies utilize…
Learning Bird's Eye View (BEV) representation from surrounding-view cameras is of great importance for autonomous driving. In this work, we propose a Geometry-guided Kernel Transformer (GKT), a novel 2D-to-BEV representation learning…
Predicting genetic mutations from whole slide images is indispensable for cancer diagnosis. However, existing work training multiple binary classification models faces two challenges: (a) Training multiple binary classifiers is inefficient…
Unsupervised representation learning of speech has been of keen interest in recent years, which is for example evident in the wide interest of the ZeroSpeech challenges. This work presents a new method for learning frame level…
Predicting phenotypes from gene expression data is a crucial task in biomedical research, enabling insights into disease mechanisms, drug responses, and personalized medicine. Traditional machine learning and deep learning rely on…
Conventionally, autoencoders are unsupervised representation learning tools. In this work, we propose a novel discriminative autoencoder. Use of supervised discriminative learning ensures that the learned representation is robust to…
The success of deep neural networks often relies on a large amount of labeled examples, which can be difficult to obtain in many real scenarios. To address this challenge, unsupervised methods are strongly preferred for training neural…
The success of deep learning heavily relies on large-scale data with comprehensive labels, which is more expensive and time-consuming to fetch in 3D compared to 2D images or natural languages. This promotes the potential of utilizing models…
Recently, a variety of acoustic tasks and related applications arised. For many acoustic tasks, the labeled data size may be limited. To handle this problem, we propose an unsupervised pre-training method using Transformer based encoder to…
Pre-trained language models have attracted increasing attention in the biomedical domain, inspired by their great success in the general natural language domain. Among the two main branches of pre-trained language models in the general…
Constructing appropriate representations of molecules lies at the core of numerous tasks such as material science, chemistry and drug designs. Recent researches abstract molecules as attributed graphs and employ graph neural networks (GNN)…
Exploring the functions of genes and gene products is crucial to a wide range of fields, including medical research, evolutionary biology, and environmental science. However, discovering new functions largely relies on expensive and…
Gene expression data represents a unique challenge in predictive model building, because of the small number of samples $(n)$ compared to the huge amount of features $(p)$. This "$n<<p$" property has hampered application of deep learning…
While machine learning is currently transforming the field of histopathology, the domain lacks a comprehensive evaluation of state-of-the-art models based on essential but complementary quality requirements beyond a mere classification…
Autoencoders exhibit impressive abilities to embed the data manifold into a low-dimensional latent space, making them a staple of representation learning methods. However, without explicit supervision, which is often unavailable, the…