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Tokens are discrete representations that allow modern deep learning to scale by transforming high-dimensional data into sequences that can be efficiently learned, generated, and generalized to new tasks. These have become foundational for…

Computer Vision and Pattern Recognition · Computer Science 2026-02-05 Levi Lingsch , Georgios Kissas , Johannes Jakubik , Siddhartha Mishra

Current foundation model for photoplethysmography (PPG) signals is challenged by the intrinsic redundancy and noise of the signal. Standard masked modeling often yields trivial solutions while contrastive methods lack morphological…

Machine Learning · Computer Science 2026-01-30 Zongheng Guo , Tao Chen , Yang Jiao , Yi Pan , Xiao Hu , Manuela Ferrario

The aim of this paper is to discuss potential advances in PET kinetic models and direct reconstruction of kinetic parameters. As a prominent example we focus on a typical task in perfusion imaging and derive a system of…

Optimization and Control · Mathematics 2014-11-20 Louise Reips , Martin Burger , Ralf Engbers

Four-dimensional scanning transmission electron microscopy (4D-STEM) provides rich, atomic-scale insights into materials structures. However, extracting specific physical properties - such as polarization directions essential for…

Spatial transcriptomics (ST) has emerged as an advanced technology that provides spatial context to gene expression. Recently, deep learning-based methods have shown the capability to predict gene expression from WSI data using ST data.…

Machine Learning · Computer Science 2024-12-10 Mingcheng Qu , Yuncong Wu , Donglin Di , Anyang Su , Tonghua Su , Yang Song , Lei Fan

Adoption of deep neural networks in fields such as economics or finance has been constrained by the lack of interpretability of model outcomes. This paper proposes a generative neural network architecture - the parameter encoder neural…

Machine Learning · Statistics 2021-06-11 Johann Pfitzinger

Parameter-Efficient Fine-Tuning (PEFT) of text-to-image models has become an increasingly popular technique with many applications. Among the various PEFT methods, Low-Rank Adaptation (LoRA) and its variants have gained significant…

Machine Learning · Computer Science 2025-08-01 Zerui Tao , Yuhta Takida , Naoki Murata , Qibin Zhao , Yuki Mitsufuji

Dynamic PET enables the quantitative estimation of physiology-related parameters and is widely utilized in research and increasingly adopted in clinical settings. Parametric imaging in dynamic PET requires kinetic modeling to estimate…

Image and Video Processing · Electrical Eng. & Systems 2025-12-23 Ziqian Huang , Boxiao Yu , Siqi Li , Savas Ozdemir , Sangjin Bae , Jae Sung Lee , Guobao Wang , Kuang Gong

In computational pathology, several foundation models have recently emerged and demonstrated enhanced learning capability for analyzing pathology images. However, adapting these models to various downstream tasks remains challenging,…

Computer Vision and Pattern Recognition · Computer Science 2024-10-22 Jeaung Lee , Jeewoo Lim , Keunho Byeon , Jin Tae Kwak

We present Patherea, a unified framework for point-based cell detection and classification that enables the development and fair evaluation of state-of-the-art methods. To support this, we introduce a large-scale dataset that replicates the…

Image and Video Processing · Electrical Eng. & Systems 2025-07-17 Dejan Štepec , Maja Jerše , Snežana Đokić , Jera Jeruc , Nina Zidar , Danijel Skočaj

Generative AI framework-based modeling and prediction of longitudinal human brain images offer an efficient mechanism to track neurodegenerative progression, essential for the assessment of diseases like Alzheimer's. Among the existing…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Ayantika Das , Keerthi Ram , Mohanasankar Sivaprakasam

Pathology foundation models (PFMs) have emerged as a core approach for learning transferable representations from whole slide images (WSIs), and they are typically benchmarked through downstream clinical endpoints. While such task level…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Bokai Zhao , Yiyang Zhang , Yuanchi Zhu , Hanqing Chao , Long Bai , Tai Ma , Minfeng Xu , Ming Song , Tianzi Jiang

Kappa distributions are widely used in space plasma physics to model velocity distribution functions with heavy tails. Parameter estimation in these distributions is, however, complicated by the fact that the kappa distribution does not…

Methodology · Statistics 2026-05-25 Leonardo Herrera-Fuenzalida , Sergio Davis

Parameter-efficient fine-tuning (PEFT) has become a popular way to adapt large pre-trained models to new tasks. Most PEFT methods update only a small subset of parameters while freezing the rest, avoiding redundant computation. As they…

Machine Learning · Computer Science 2025-08-25 Sungmin Kang , Jisoo Kim , Salman Avestimehr , Sunwoo Lee

Prostate Cancer (PCa) is a prevalent disease among men, and multi-parametric MRIs offer a non-invasive method for its detection. While MRI-based deep learning solutions have shown promise in supporting PCa diagnosis, acquiring sufficient…

Image and Video Processing · Electrical Eng. & Systems 2024-06-04 Meng Zhou , Amoon Jamzad , Jason Izard , Alexandre Menard , Robert Siemens , Parvin Mousavi

Parameter-efficient fine-tuning (PEFT) has emerged as a promising paradigm for adapting pretrained models under limited data conditions. However, most existing PEFT methods are designed for matrix-structured parameters and are not well…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Guanghua He , Hancan Zhu , Gaohang Yu , An Zhang

The power of foundation models (FMs) lies in their capacity to learn highly expressive representations that can be adapted to a broad spectrum of tasks. However, these pretrained models require additional training stages to become effective…

Machine Learning · Computer Science 2025-10-24 Jacob L. Block , Sundararajan Srinivasan , Liam Collins , Aryan Mokhtari , Sanjay Shakkottai

Foundation models have shown superior performance for speech emotion recognition (SER). However, given the limited data in emotion corpora, finetuning all parameters of large pre-trained models for SER can be both resource-intensive and…

Audio and Speech Processing · Electrical Eng. & Systems 2024-04-02 Nineli Lashkarashvili , Wen Wu , Guangzhi Sun , Philip C. Woodland

Graph foundation models (GFM) aim to acquire transferable knowledge by pre-training on diverse graphs, which can be adapted to various downstream tasks. However, domain shift in graphs is inherently two-dimensional: graphs differ not only…

Computation and Language · Computer Science 2026-03-12 Xingtong Yu , Shenghua Ye , Ruijuan Liang , Chang Zhou , Hong Cheng , Xinming Zhang , Yuan Fang

A Profile Mixture Model is a model of protein evolution, describing sequence data in which sites are assumed to follow many related substitution processes on a single evolutionary tree. The processes depend in part on different amino acid…

Populations and Evolution · Quantitative Biology 2020-07-07 Samaneh Yourdkhani , Elizabeth S. Allman , John A. Rhodes
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